ChemicalBook > CAS DataBase List > 6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE

6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE

Product Name: 6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE
CAS No.: 2092-49-1
Chemical Name: 6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE
Synonyms: DIVANILLIN;5,5'-Bivanillin;Dehydrovanillin;dehydrodivanillin;6 6'-DIHYDROXY-5 5'-DIMETHOXY-(1 1'-BIP&;6,6'-dihydroxy-5,5'-dimethoxy-(1,1'-biphen -yl)-3;5,5'-Dimethoxy-6,6'-dihydroxybiphenyl-3,3'-dicarbaldehyde;6,6'-dihydroxy-5,5'-dimethoxybiphenyl-3,3'-dicarbaldehyde;3,3'-Biphenyldicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy-;6,6'-Dihydroxy-5,5'-dimethoxy-1,1'-biphenyl-3,3'-dicarbaldehyde
CBNumber: CB2445663
Molecular Formula: C16H14O6
Formula Weight: 302.28
MOL File: 2092-49-1.mol

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6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE Property

Melting point:: 315 °C(lit.)
Boiling point:: 486.3±45.0 °C(Predicted)
Density: 1.356±0.06 g/cm3(Predicted)
FEMA: 4107 | DIVANILLIN
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: DMSO (Slightly), Ethanol (Slightly, Heated), Methanol (Slightly)
form: Solid
pka: 6.62±0.48(Predicted)
color: Dark Brown to Very Dark Gray
Odor: at 100.00 %. fruity vanilla
Odor Type: vanilla
JECFA Number: 1881
LogP: 1.57

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Safety

Hazard Codes: Xn
Risk Statements: 22-36
Safety Statements: 26-36

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: D233040
Product name: Dehydrodivanillin(~90%,containsupto10%unknowninorganics)
Packaging: 500mg
Price: $90
Updated: 2021/12/16

Usbiological

Product number: 446024
Product name: Dehydrodivanillin
Packaging: 100mg
Price: $312
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD71561
Product name: 6,6′-Dihydroxy-5,5′-dimethoxy-[1,1′-biphenyl]-3,3′-dicarboxaldehyde
Packaging: 250mg
Price: $50
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD71561
Product name: 6,6′-Dihydroxy-5,5′-dimethoxy-[1,1′-biphenyl]-3,3′-dicarboxaldehyde
Packaging: 500mg
Price: $80
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD71561
Product name: 6,6′-Dihydroxy-5,5′-dimethoxy-[1,1′-biphenyl]-3,3′-dicarboxaldehyde
Packaging: 1g
Price: $140
Updated: 2021/12/16

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6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE Chemical Properties,Usage,Production

Chemical Properties

White solid; fruity vanilla aroma.

Uses

Dehydrodivanillin is used as a reactant in the preparation of antioxidant phenolic diaryl hydrazones as antiangiogenic agents for atherosclerosis therapy. Also used as a taste enhancer.

Synthesis

121-33-5

2092-49-1

General procedure for the synthesis of 6,6'-dihydroxy-5,5'-dimethoxy-(1,1'-biphenyl)-3,3'-dicarboxaldehyde from vanillin: 5 g of vanillin (33 mmol, purchased from Wako Pure Chemical Industries, Ltd.) was dissolved in 200 ml of ion-exchanger water preheated to 80 °C. To this solution, 200 mg (0.72 mmol) of iron sulfate (purchased from Wako Pure Chemical Industries, Ltd.) and 5 g (19 mmol) of potassium peroxydisulfate (purchased from Wako Pure Chemical Industries, Ltd.) were sequentially added, followed by heating and refluxing for 1 hr at 120 °C. Upon completion of the reaction, unreacted vanillin was removed by thermal filtration to afford intermediate (a1) in 97% yield.

References

[1] Bioorganic and Medicinal Chemistry, 2005, vol. 13, # 7, p. 2537 - 2546
[2] European Journal of Organic Chemistry, 2013, # 1, p. 173 - 179
[3] Patent: JP2017/14122, 2017, A. Location in patent: Paragraph 0051
[4] Journal of Molecular Catalysis B: Enzymatic, 2016, vol. 125, p. 34 - 41
[5] Journal of Medicinal Chemistry, 2008, vol. 51, # 11, p. 3171 - 3181

6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE manufacturers

Career Henan Chemical Co

Product: 6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE 2092-49-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 90%-99.9%
Supply Ability: 500kg
Release date: 2019-07-12

Career Henan Chemical Co

Product: 6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE 2092-49-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 90%-99.9%
Supply Ability: 500kg
Release date: 2019-07-09

2092-49-1, 6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDERelated Search:

Vanillin ISOEUGENOL 3-Hydroxy-2-methyl-4H-pyran-4-one

6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE

6,6'-dihydroxy-5,5'-dimethoxy-(1,1'-biphen -yl)-3

6 6'-DIHYDROXY-5 5'-DIMETHOXY-(1 1'-BIP&

dehydrodivanillin

DIVANILLIN

6,6'-dihydroxy-5,5'-dimethoxybiphenyl-3,3'-dicarbaldehyde

2,2'-Dihydroxy-3,3'-dimethoxy-1,1'-biphenyl-5,5'-dicarbaldehyde

5,5'-Bivanillin

5,5'-Dimethoxy-6,6'-dihydroxybiphenyl-3,3'-dicarbaldehyde

6,6'-Dihydroxy-5,5'-dimethoxy-1,1'-biphenyl-3,3'-dicarbaldehyde

[1,1'-Biphenyl]-3,3'-dicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy-

3,3-Biphenyldicarboxaldehyde, 6,6-dihydroxy-5,5-diMethoxy- (8CI)

Dehydrovanillin

(1,1'-Biphenyl)-3,3'-dicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy- (9CI)

3-(5-formyl-2-hydroxy-3-methoxy-phenyl)-4-hydroxy-5-methoxy-benzaldehyde

3-(5-formyl-2-hydroxy-3-methoxyphenyl)-4-hydroxy-5-methoxybenzaldehyde

3,3'-Biphenyldicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy-

3,3'-Biphenyldicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy- (8

4-hydroxy-3-(2-hydroxy-5-methanoyl-3-methoxy-phenyl)-5-methoxy-benzaldehyde

6,6'-dihydroxy-5,5'-dimethoxy-[1,1'-biphenyl]-3,3'-dicarbaldehyde

2092-49-1

HOC6H2OCH3CHO2