ChemicalBook > CAS DataBase List > 6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE

6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE

Product Name
6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE
CAS No.
2092-49-1
Chemical Name
6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE
Synonyms
DIVANILLIN;5,5'-Bivanillin;Dehydrovanillin;dehydrodivanillin;6 6'-DIHYDROXY-5 5'-DIMETHOXY-(1 1'-BIP&;6,6'-dihydroxy-5,5'-dimethoxy-(1,1'-biphen -yl)-3;5,5'-Dimethoxy-6,6'-dihydroxybiphenyl-3,3'-dicarbaldehyde;6,6'-dihydroxy-5,5'-dimethoxybiphenyl-3,3'-dicarbaldehyde;3,3'-Biphenyldicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy-;6,6'-Dihydroxy-5,5'-dimethoxy-1,1'-biphenyl-3,3'-dicarbaldehyde
CBNumber
CB2445663
Molecular Formula
C16H14O6
Formula Weight
302.28
MOL File
2092-49-1.mol
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6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE Property

Melting point:
315 °C(lit.)
Boiling point:
486.3±45.0 °C(Predicted)
Density 
1.356±0.06 g/cm3(Predicted)
FEMA 
4107 | DIVANILLIN
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMSO (Slightly), Ethanol (Slightly, Heated), Methanol (Slightly)
form 
Solid
pka
6.62±0.48(Predicted)
color 
Dark Brown to Very Dark Gray
Odor
at 100.00 %. fruity vanilla
Odor Type
vanilla
JECFA Number
1881
LogP
1.57
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36
Safety Statements 
26-36
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
D233040
Product name
Dehydrodivanillin(~90%,containsupto10%unknowninorganics)
Packaging
500mg
Price
$90
Updated
2021/12/16
Usbiological
Product number
446024
Product name
Dehydrodivanillin
Packaging
100mg
Price
$312
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD71561
Product name
6,6′-Dihydroxy-5,5′-dimethoxy-[1,1′-biphenyl]-3,3′-dicarboxaldehyde
Packaging
5G
Price
$450
Updated
2021/12/16
Matrix Scientific
Product number
157259
Product name
6,6'-Dihydroxy-5,5'-dimethoxybiphenyl-3,3'-dicarbaldehyde
Packaging
1g
Price
$165
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD71561
Product name
6,6′-Dihydroxy-5,5′-dimethoxy-[1,1′-biphenyl]-3,3′-dicarboxaldehyde
Packaging
2g
Price
$260
Updated
2021/12/16
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6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE Chemical Properties,Usage,Production

Chemical Properties

White solid; fruity vanilla aroma.

Uses

Dehydrodivanillin is used as a reactant in the preparation of antioxidant phenolic diaryl hydrazones as antiangiogenic agents for atherosclerosis therapy. Also used as a taste enhancer.

Synthesis

121-33-5

2092-49-1

General procedure for the synthesis of 6,6'-dihydroxy-5,5'-dimethoxy-(1,1'-biphenyl)-3,3'-dicarboxaldehyde from vanillin: 5 g of vanillin (33 mmol, purchased from Wako Pure Chemical Industries, Ltd.) was dissolved in 200 ml of ion-exchanger water preheated to 80 °C. To this solution, 200 mg (0.72 mmol) of iron sulfate (purchased from Wako Pure Chemical Industries, Ltd.) and 5 g (19 mmol) of potassium peroxydisulfate (purchased from Wako Pure Chemical Industries, Ltd.) were sequentially added, followed by heating and refluxing for 1 hr at 120 °C. Upon completion of the reaction, unreacted vanillin was removed by thermal filtration to afford intermediate (a1) in 97% yield.

References

[1] Bioorganic and Medicinal Chemistry, 2005, vol. 13, # 7, p. 2537 - 2546
[2] European Journal of Organic Chemistry, 2013, # 1, p. 173 - 179
[3] Patent: JP2017/14122, 2017, A. Location in patent: Paragraph 0051
[4] Journal of Molecular Catalysis B: Enzymatic, 2016, vol. 125, p. 34 - 41
[5] Journal of Medicinal Chemistry, 2008, vol. 51, # 11, p. 3171 - 3181

6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE Suppliers

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View Lastest Price from 6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE manufacturers

Career Henan Chemical Co
Product
6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE 2092-49-1
Price
US $1.00/KG
Min. Order
1KG
Purity
90%-99.9%
Supply Ability
500kg
Release date
2019-07-12
Career Henan Chemical Co
Product
6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE 2092-49-1
Price
US $1.00/KG
Min. Order
1KG
Purity
90%-99.9%
Supply Ability
500kg
Release date
2019-07-09

2092-49-1, 6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDERelated Search:

Vanillin ISOEUGENOL 3-Hydroxy-2-methyl-4H-pyran-4-one

  • 6,6'-DIHYDROXY-5,5'-DIMETHOXY-[1,1'-BIPHENYL]-3,3'-DICARBOXALDEHYDE
  • 6,6'-dihydroxy-5,5'-dimethoxy-(1,1'-biphen -yl)-3
  • 6 6'-DIHYDROXY-5 5'-DIMETHOXY-(1 1'-BIP&
  • dehydrodivanillin
  • DIVANILLIN
  • 6,6'-dihydroxy-5,5'-dimethoxybiphenyl-3,3'-dicarbaldehyde
  • 2,2'-Dihydroxy-3,3'-dimethoxy-1,1'-biphenyl-5,5'-dicarbaldehyde
  • 5,5'-Bivanillin
  • 5,5'-Dimethoxy-6,6'-dihydroxybiphenyl-3,3'-dicarbaldehyde
  • 6,6'-Dihydroxy-5,5'-dimethoxy-1,1'-biphenyl-3,3'-dicarbaldehyde
  • [1,1'-Biphenyl]-3,3'-dicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy-
  • 3,3-Biphenyldicarboxaldehyde, 6,6-dihydroxy-5,5-diMethoxy- (8CI)
  • Dehydrovanillin
  • (1,1'-Biphenyl)-3,3'-dicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy- (9CI)
  • 3-(5-formyl-2-hydroxy-3-methoxy-phenyl)-4-hydroxy-5-methoxy-benzaldehyde
  • 3-(5-formyl-2-hydroxy-3-methoxyphenyl)-4-hydroxy-5-methoxybenzaldehyde
  • 3,3'-Biphenyldicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy-
  • 3,3'-Biphenyldicarboxaldehyde, 6,6'-dihydroxy-5,5'-dimethoxy- (8
  • 4-hydroxy-3-(2-hydroxy-5-methanoyl-3-methoxy-phenyl)-5-methoxy-benzaldehyde
  • 6,6'-dihydroxy-5,5'-dimethoxy-[1,1'-biphenyl]-3,3'-dicarbaldehyde
  • 2092-49-1
  • HOC6H2OCH3CHO2