ChemicalBook > CAS DataBase List > 3-BROMO-PHENYL ACETATE

3-BROMO-PHENYL ACETATE

Product Name
3-BROMO-PHENYL ACETATE
CAS No.
35065-86-2
Chemical Name
3-BROMO-PHENYL ACETATE
Synonyms
Pemetrexed Impurity 76;3-BROMO-PHENYL ACETATE;1-Bromo-3-acetoxybenzene;1-Acetoxy-3-bromobenzene;Phenol, 3-bromo-, acetate;Phenol, 3-bromo-, 1-acetate;3-Bromo-phenyl acetate, 98 %;3-bromoacetic acid phenyl ester
CBNumber
CB2465427
Molecular Formula
C8H7BrO2
Formula Weight
215.04
MOL File
35065-86-2.mol
More
Less

3-BROMO-PHENYL ACETATE Property

Boiling point:
149℃ (40 Torr)
Density 
1.501±0.06 g/cm3 (20 ºC 760 Torr)
Flash point:
108.0±22.6℃
storage temp. 
Store at room temperature
Appearance
Light yellow to yellow Liquid
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
B700528
Product name
3-BromophenylAcetate
Packaging
50mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
Z4634
Product name
3-Bromophenylacetate
Packaging
1g
Price
$67
Updated
2021/12/16
Matrix Scientific
Product number
119647
Product name
3-Bromophenyl acetate
Purity
95+%
Packaging
1g
Price
$90
Updated
2021/12/16
Matrix Scientific
Product number
119647
Product name
3-Bromophenyl acetate
Purity
95+%
Packaging
5g
Price
$270
Updated
2021/12/16
Matrix Scientific
Product number
119647
Product name
3-Bromophenyl acetate
Purity
95+%
Packaging
10g
Price
$450
Updated
2021/12/16
More
Less

3-BROMO-PHENYL ACETATE Chemical Properties,Usage,Production

Synthesis Reference(s)

The Journal of Organic Chemistry, 48, p. 1542, 1983 DOI: 10.1021/jo00157a035

Synthesis

591-20-8

75-36-5

35065-86-2

1. Acetyl chloride (61.7 mL, 867 mmol) was added dropwise to a solution of 3-bromophenol (150 g, 867 mmol) and pyridine (70.0 mL, 867 mmol) in dichloromethane (1000 mL) in an ice bath over a controlled time period of 1 hour. After the dropwise addition, the reaction mixture was stirred at room temperature for 18 hours. 2. After completion of the reaction, water (500 mL) was added to the reaction mixture for dilution and the organic layer was separated. The aqueous layer was extracted with dichloromethane (4 x 150 mL) and the organic layers were combined. 3. The combined organic layers were washed sequentially with 2.5N NaHSO4 (3×150mL), 3N NaOH (3×150mL), water (2×200mL) and brine (2×200mL). 4. The washed organic layer was dried over anhydrous Na2SO4, filtered and the solvent was evaporated to give phenyl 3-bromoacetate as a pink liquid (36.0 g, 86% yield). 5. The product was characterized by GC/MS and 1H NMR: GC/MS data: m/z 214 (M)+ (C8H7BrO2 calculated value 215.04). 1H NMR (DMSO-d6) δ: 7.44-7.48 (ddd, 1H, J1=1.0Hz, J2=2.0Hz, J3=8.1Hz, Ar-H), 7.43 (t, 1H, J1=1.0Hz, J2=2.0Hz, Ar-H). (t, 1H, J=2.1Hz, Ar-H), 7.38 (t, 1H, J=8.1Hz, Ar-H), 7.14-7.18 (ddd, 1H, J1=1.0Hz, J2=2.2Hz, J3=8.1Hz, Ar-H), 2.26 (s, 3H, CH3).

References

[1] Patent: WO2007/88450, 2007, A2. Location in patent: Page/Page column 21
[2] Patent: US2009/202478, 2009, A1
[3] Patent: US9138427, 2015, B2. Location in patent: Page/Page column 293
[4] Pharmacy and Pharmacology Communications, 1999, vol. 5, # 5, p. 323 - 329
[5] Patent: US2008/188521, 2008, A1. Location in patent: Page/Page column 12

3-BROMO-PHENYL ACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3-BROMO-PHENYL ACETATE Suppliers

China 72 France 2 India 1 United Kingdom 3 United States 4 Global 82
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jinan Trio PharmaTech Co., Ltd.
Tel
0531-88811783
Fax
+86 (531) 55696010 QQ 1762738062
Email
sales@trio-pharmatech.com
Country
China
ProdList
1856
Advantage
62
Anichem Inc.
Tel
0512-69369885
Fax
0512-69369880
Email
sales@anichem.com.cn
Country
China
ProdList
495
Advantage
55
Shanghai Hong-chuang Pharma Tech Co., Ltd.
Tel
18151128828
Fax
-
Email
hc-sales@foxmail.com
Country
China
ProdList
2647
Advantage
55
Shanghai Xingui Biotechnology Co., Ltd.
Tel
15121041756
Email
xingui2022@126.com
Country
China
ProdList
9986
Advantage
58
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Changzhou Anxuan Chemical, Co., Ltd.
Tel
13912302692 13912302692;
Fax
0519-88064678
Email
sales@anxuanchem.com
Country
China
ProdList
4828
Advantage
58
ShangHai Angti Biotechnology Co., Ltd.
Tel
13764913901
Fax
-
Email
info@angtibio.com
Country
China
ProdList
4984
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60

35065-86-2, 3-BROMO-PHENYL ACETATERelated Search:

PENTABROMOPHENYL METHACRYLATE PENTABROMOPHENYL ACRYLATE 4-ACETOXY-2-BROMO-5-METHOXYBENZALDEHYDE 98 AKOS B005165 AKOS B005166 SPECS AN-655/15530009 AKOS B005162 ACETIC ACID 5-BROMO-2-ETHOXY-4-FORMYL-PHENYL ESTER AKOS B005251 AKOS B005159 AKOS B005250 AKOS B005161 7-bromo-4-methyl-2H-chromen-2-one AKOS B005248 AKOS B005164 AKOS B005160 AKOS B005158 AKOS B005168

  • 3-BROMO-PHENYL ACETATE
  • 3-Bromo-phenyl acetate, 98 %
  • 1-Acetoxy-3-bromobenzene
  • 1-Bromo-3-acetoxybenzene
  • Phenol, 3-bromo-, acetate
  • Phenol, 3-bromo-, 1-acetate
  • Pemetrexed Impurity 76
  • 3-bromoacetic acid phenyl ester
  • 35065-86-2
  • Anisoles, Alkyloxy Compounds & Phenylacetates
  • Bromine Compounds