ChemicalBook > CAS DataBase List > 5-Aminomethyluridine
5-Aminomethyluridine
- Product Name
- 5-Aminomethyluridine
- CAS No.
- 190448-73-8
- Chemical Name
- 5-Aminomethyluridine
- Synonyms
- 5-Aminomethyluridine;Uridine, 5-(aminomethyl)-
- CBNumber
- CB24658115
- Molecular Formula
- C10H15N3O6
- Formula Weight
- 273.24
- MOL File
- 190448-73-8.mol
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5-Aminomethyluridine Property
- Density
- 1.621±0.06 g/cm3(Predicted)
- pka
- 8.12±0.10(Predicted)
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5-Aminomethyluridine Chemical Properties,Usage,Production
Uses
5-(Aminomethyl)uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93. DOI:10.3390/molecules16097980
[2] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
5-Aminomethyluridine Preparation Products And Raw materials
Raw materials
Preparation Products
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