ChemicalBook > CAS DataBase List > BPK-29
BPK-29
- Product Name
- BPK-29
- CAS No.
- 2143467-62-1
- Chemical Name
- BPK-29
- Synonyms
- BPK-29;BPK 29,BPK29;BPK-29 >=98% (HPLC);Acetamide, 2-chloro-N-[hexahydro-1-[4-(4-morpholinyl)benzoyl]-1H-azepin-4-yl]-N-(phenylmethyl)-
- CBNumber
- CB24667676
- Molecular Formula
- C26H32ClN3O3
- Formula Weight
- 470
- MOL File
- 2143467-62-1.mol
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BPK-29 Property
- Boiling point:
- 686.6±55.0 °C(Predicted)
- Density
- 1.26±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 3.88±0.40(Predicted)
- color
- White to off-white
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BPK-29 Chemical Properties,Usage,Production
Biological Activity
BPK-29 is a potent and selective NR0B1 ligand th at covalently binds to NR0B1 Cys 274. BPK-29 inhibits the NR0B1-SNW1 interaction. It inhibits the anchorage-independent growth of KEAP1-mutant cancer cells.', 'BPK-29 is a small molecule inhibitor th at blocks the nuclear factor erythroid 2–related factor 2 (NRF2) pathway. It targets the cysteine 274 residue in the nuclear receptor subfamily 0 group B member 1 (NR0B1) and disrupts protein-protein interactions in non-small-cell lung cancer (NSCLC) cell proteomes.
BPK-29 Preparation Products And Raw materials
Raw materials
Preparation Products
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BPK-29 Suppliers
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