5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl) adenosine

Product Name: 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl) adenosine
CAS No.: 1384253-67-1
Chemical Name: 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl) adenosine
Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)adenosine;5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl) adenosine;2'-O-(2-Methoxyethyl)-5'-O-bis(4-methoxyphenyl)phenylmethyladenosine;Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-;(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-(2-methoxyethoxy)oxolan-3-ol;(2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-ol
CBNumber: CB24672472
Molecular Formula: C34H37N5O7
Formula Weight: 627.69
MOL File: 1384253-67-1.mol

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5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl) adenosine Property

Boiling point:: 821.6±75.0 °C(Predicted)
Density: 1.34±0.1 g/cm3(Predicted)
pka: 13.07±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl) adenosine Chemical Properties,Usage,Production

Uses

5’-O-(4,4’-Dimethoxytrityl)-2’-O-(2-methoxyethyl) adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

References

[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020

5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl) adenosine Preparation Products And Raw materials

Raw materials

Preparation Products

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5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl) adenosine Suppliers

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1384253-67-1