4-CHLOROMERCURIBENZOIC ACID
- Product Name
- 4-CHLOROMERCURIBENZOIC ACID
- CAS No.
- 59-85-8
- Chemical Name
- 4-CHLOROMERCURIBENZOIC ACID
- Synonyms
- DYR;P-CMB;P-CMBA;usafd-3;NSC 32866;DHFR from mouse;p-Chlormercuribenzoic Acid;P-CHLOROMERCURIBENZOIC ACID;4-CHLOROMERCURIBENZOIC ACID;p-(chloromercuri)-benzoicaci
- CBNumber
- CB2470894
- Molecular Formula
- C7H5ClHgO2
- Formula Weight
- 357.16
- MOL File
- 59-85-8.mol
4-CHLOROMERCURIBENZOIC ACID Property
- Melting point:
- 287 °C (dec.)(lit.)
- storage temp.
- -20°C Freezer
- solubility
- Aqueous Base (Slightly, Heated),
- form
- solid
- BRN
- 3662892
- CAS DataBase Reference
- 59-85-8(CAS DataBase Reference)
- EPA Substance Registry System
- Mercurate(1-), (4-carboxylatophenyl)chloro-, hydrogen (59-85-8)
Safety
- Hazard Codes
- T+,N
- Risk Statements
- 26/27/28-33-50/53
- Safety Statements
- 13-28-36-45-60-61
- RIDADR
- UN 2025 6.1/PG 2
- WGK Germany
- 3
- RTECS
- OV8050000
- F
- 3-8-10
- TSCA
- Yes
- HazardClass
- 6.1(a)
- PackingGroup
- II
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- SRP6119
- Product name
- DHFR from mouse
- Purity
- recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
- Packaging
- 100μG
- Price
- $522
- Updated
- 2023/06/20
- Product number
- C5913
- Product name
- 4-Chloromercuribenzoic acid
- Purity
- cysteine active site modifier
- Packaging
- 5g
- Price
- $133
- Updated
- 2022/05/15
- Product number
- C367800
- Product name
- 4-Chloromercuribenzoic acid
- Packaging
- 2.5g
- Price
- $595
- Updated
- 2021/12/16
- Product number
- C367800
- Product name
- 4-Chloromercuribenzoic acid
- Packaging
- 1g
- Price
- $310
- Updated
- 2021/12/16
- Product number
- 268399
- Product name
- 4-Chloromercuribenzoic acid
- Packaging
- 500mg
- Price
- $410
- Updated
- 2021/12/16
4-CHLOROMERCURIBENZOIC ACID Chemical Properties,Usage,Production
Chemical Properties
4-CHLOROMERCURIBENZOIC ACID is White Solid
Uses
4-CHLOROMERCURIBENZOIC ACID can be used to inhibit some enzymes that require unmodified cysteine residues (e.g., adenylyl cyclase).
Uses
A useful sulfhydryl reagent that reacts with Histidine 225C, a residue of the NhaA-Na/H Antiporter of Escherichia Coli
Definition
ChEBI: P-chloromercuribenzoic acid is a mercuribenzoic acid and a chlorine molecular entity. It is functionally related to a benzoic acid.
Safety Profile
Poison by intraperitoneal route. See also MERCURY COMPOUNDS. When heated to decomposition it emits very toxic fumes of Cland Hg.
Purification Methods
Its suspension in water is stirred with enough 1M NaOH to dissolve most of it: a small amount of insoluble matter is removed by centrifugation. The chloromercuribenzoic acid is then precipitated by adding 1M HCl and centrifuged off. The precipitation is repeated twice. Finally, the precipitate is washed three times with distilled water (by centrifugation), then dried in a thin layer under vacuum over P2O5 [Boyer J Am Chem Soc 76 4331 1954]. Chloromethylphosphonic acid dichloride [1983 -26 -2] M 167.4, b 50o/0.5mm, 52 -53(59)o/2mm, 63-65o/3mm, 78 -79o/10mm, 87 -88o/15mm, 102-103o/30mm, d 4 1.638, n D 1.4971. It is fractionally distilled using a short Claisen column and redistilled. The aniline salt has m 199-201o. The 3 1P NMR has a single peak at -38±2 ppm from 85% H3PO4. [Kinnear & Perren J Chem Soc 3437 1952, NMR: van Wazer et al. J Am Chem Soc 78 5715 1956, McConnell et al. J Org Chem 22 462 1957, Beilstein 1 III 2593, 1 IV 3068.]
4-CHLOROMERCURIBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-CHLOROMERCURIBENZOIC ACID manufacturers
- Product
- p-chloromercuribenzoic acid 59-85-8
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-09