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4-CHLOROMERCURIBENZOIC ACID

Product Name
4-CHLOROMERCURIBENZOIC ACID
CAS No.
59-85-8
Chemical Name
4-CHLOROMERCURIBENZOIC ACID
Synonyms
DYR;P-CMB;P-CMBA;usafd-3;NSC 32866;DHFR from mouse;p-Chlormercuribenzoic Acid;P-CHLOROMERCURIBENZOIC ACID;4-CHLOROMERCURIBENZOIC ACID;p-(chloromercuri)-benzoicaci
CBNumber
CB2470894
Molecular Formula
C7H5ClHgO2
Formula Weight
357.16
MOL File
59-85-8.mol
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4-CHLOROMERCURIBENZOIC ACID Property

Melting point:
287 °C (dec.)(lit.)
storage temp. 
-20°C Freezer
solubility 
Aqueous Base (Slightly, Heated),
form 
solid
BRN 
3662892
CAS DataBase Reference
59-85-8(CAS DataBase Reference)
EPA Substance Registry System
Mercurate(1-), (4-carboxylatophenyl)chloro-, hydrogen (59-85-8)
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Safety

Hazard Codes 
T+,N
Risk Statements 
26/27/28-33-50/53
Safety Statements 
13-28-36-45-60-61
RIDADR 
UN 2025 6.1/PG 2
WGK Germany 
3
RTECS 
OV8050000
3-8-10
TSCA 
Yes
HazardClass 
6.1(a)
PackingGroup 
II
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SRP6119
Product name
DHFR from mouse
Purity
recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
Packaging
100μG
Price
$522
Updated
2023/06/20
Sigma-Aldrich
Product number
C5913
Product name
4-Chloromercuribenzoic acid
Purity
cysteine active site modifier
Packaging
5g
Price
$133
Updated
2022/05/15
TRC
Product number
C367800
Product name
4-Chloromercuribenzoic acid
Packaging
2.5g
Price
$595
Updated
2021/12/16
TRC
Product number
C367800
Product name
4-Chloromercuribenzoic acid
Packaging
1g
Price
$310
Updated
2021/12/16
Usbiological
Product number
268399
Product name
4-Chloromercuribenzoic acid
Packaging
500mg
Price
$410
Updated
2021/12/16
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4-CHLOROMERCURIBENZOIC ACID Chemical Properties,Usage,Production

Chemical Properties

4-CHLOROMERCURIBENZOIC ACID is White Solid

Uses

4-CHLOROMERCURIBENZOIC ACID can be used to inhibit some enzymes that require unmodified cysteine residues (e.g., adenylyl cyclase).

Uses

A useful sulfhydryl reagent that reacts with Histidine 225C, a residue of the NhaA-Na/H Antiporter of Escherichia Coli

Definition

ChEBI: P-chloromercuribenzoic acid is a mercuribenzoic acid and a chlorine molecular entity. It is functionally related to a benzoic acid.

Safety Profile

Poison by intraperitoneal route. See also MERCURY COMPOUNDS. When heated to decomposition it emits very toxic fumes of Cland Hg.

Purification Methods

Its suspension in water is stirred with enough 1M NaOH to dissolve most of it: a small amount of insoluble matter is removed by centrifugation. The chloromercuribenzoic acid is then precipitated by adding 1M HCl and centrifuged off. The precipitation is repeated twice. Finally, the precipitate is washed three times with distilled water (by centrifugation), then dried in a thin layer under vacuum over P2O5 [Boyer J Am Chem Soc 76 4331 1954]. Chloromethylphosphonic acid dichloride [1983 -26 -2] M 167.4, b 50o/0.5mm, 52 -53(59)o/2mm, 63-65o/3mm, 78 -79o/10mm, 87 -88o/15mm, 102-103o/30mm, d 4 1.638, n D 1.4971. It is fractionally distilled using a short Claisen column and redistilled. The aniline salt has m 199-201o. The 3 1P NMR has a single peak at -38±2 ppm from 85% H3PO4. [Kinnear & Perren J Chem Soc 3437 1952, NMR: van Wazer et al. J Am Chem Soc 78 5715 1956, McConnell et al. J Org Chem 22 462 1957, Beilstein 1 III 2593, 1 IV 3068.]

4-CHLOROMERCURIBENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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4-CHLOROMERCURIBENZOIC ACID Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Guangzhou Jhd Chemical Reagent Co., Ltd.
Tel
020-84383047
Fax
020-84380294
Email
sales@jhd.com.cn
Country
China
ProdList
9186
Advantage
65
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
56902
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-029-89586680 +86-18192503167
Fax
+86-29-88380327
Email
1026@dideu.com
Country
China
ProdList
7724
Advantage
58
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View Lastest Price from 4-CHLOROMERCURIBENZOIC ACID manufacturers

Career Henan Chemical Co
Product
p-chloromercuribenzoic acid 59-85-8
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
200kg
Release date
2020-01-09

59-85-8, 4-CHLOROMERCURIBENZOIC ACIDRelated Search:


  • P-(CHLOROMERCURIO)BENZOIC ACID
  • P-CHLOROMERCURIBENZOIC ACID
  • P-CMB
  • P-CMBA
  • (p-Carboxyphenyl)chloromercury
  • usafd-3
  • 4-(Chloromercuric)benzoic acid
  • 4-(CHLOROMERCURIO)BENZOIC ACID
  • 4-CHLOROMERCURIBENZOIC ACID
  • 4-(HYDROXYMERCURI)BENZOIC ACID
  • 4-(HYDROXYMERCURIO)BENZOIC ACID
  • P-CHLOROMERCURIBENZOIC ACID, FREE ACID
  • 4-(CHLOROMERCURI)BENZOIC ACID 95% (&
  • Mercurate(1-), (4-carboxylatophenyl)chloro-, hydrogen
  • NSC 32866
  • p-Chlormercuribenzoic Acid
  • PARA-CHLOROMERCURIBENZOICACID
  • 4-CHLOROMERCURIBENZOIC ACID 98+%
  • 4-(Chloromercurio)benzoic acid, 4-(Hydroxymercuri)benzoic acid
  • (p-Carboxyphenyl)chloromercury(II)
  • p-(Chloromercurio(II))benzoic acid
  • p-[Chloromercurio(II)]benzoic acid
  • (4-carboxylatophenyl)chloro-mercurate(1-hydrogen
  • (4-carboxyphenyl)chloromercury
  • (p-carboxyphenyl)chloro-mercur
  • 4-carboxyphenylmercuricchloride
  • p-(chloromercuri)-benzoicaci
  • p-carboxyphenylmercuricchloride
  • p-chloro-mercuricbenzoicacid
  • DHFR from mouse
  • DYR
  • 4-CHLOROMERCURIBENZOIC ACID ISO 9001:2015 REACH
  • 59-85-8
  • C7H5ClHgO2
  • ClHgC6H4CO2H
  • C7H5HClgO2
  • C7H4ClHgO2H
  • Application Index
  • Biochemicals and Reagents
  • BioChemical
  • Cell Signaling Enzymes
  • Inhibitors
  • Reagents for Protein Sequencing
  • Protein Analysis
  • Protein Sequencing
  • Proteomics and Protein Expression
  • Dihydrofolate reductase
  • Enzymes, Inhibitors, and Substrates
  • Folic Acid Metabolism
  • Inhibitors and Substrates
  • L to O
  • A to C
  • alpha
  • and Substrates
  • Apoptosis Enzymes
  • Application Index
  • Asparaginase
  • Biochemicals and Reagents