HOECHST 33258

Product Name: HOECHST 33258
CAS No.: 23491-44-3
Chemical Name: HOECHST 33258
Synonyms: pibenzimol;Bisbenzimidazol;bisbenzimidazole;BISBENZIMIDE H 33258;hoechst 33258 (bisbenzimide);CELLSTAIN- HOECHST 33258 SOLUTION;bis-benzimide (hydroxyphenyl form);BISBENZIMIDE TRIHYDROCHLORIDE HYDRATE;bisbenzimide trihydrochloride cell*culture tested;4-[6'-(4-Methylpiperazino)-6,2'-bi[1H-benzimidazole]-2-yl]phenol
CBNumber: CB2475309
Molecular Formula: C25H24N6O
Formula Weight: 424.5
MOL File: 23491-44-3.mol

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HOECHST 33258 Property

Melting point:: 314 °C
Boiling point:: 746.9±70.0 °C(Predicted)
Density: 1.355±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: H₂O: 10 mg/mL
form: powder
pka: 9.23±0.15(Predicted)
color: Light yellow to yellow
Stability:: Stable. Incompatible with strong oxidizing agents. Light sensitive.
EPA Substance Registry System: Phenol, 4-[5-(4-methyl-1-piperazinyl)[2,5'-bi-1H-benzimidazol]-2'-yl]- (23491-44-3)

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: SM1140500
F: 3-8-10

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: CBL0001541
Product name: BIS-BENZIMIDE TRIHYDROCHLORIDE HYDRATE
Purity: 95.00%
Packaging: 5MG
Price: $496.35
Updated: 2021/12/16

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HOECHST 33258 Chemical Properties,Usage,Production

Chemical Properties

yellow solid

Uses

Hoechst 33258 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].

Definition

ChEBI: Pibenzimol is a bibenzimidazole and a N-methylpiperazine. It has a role as a fluorochrome and an anthelminthic drug.

References

[1] Wang XJ, et al. Newly synthesized bis-benzimidazole derivatives exerting anti-tumor activity through inductionof apoptosis and autophagy. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6297-300. DOI:10.1016/j.bmcl.2012.06.102
[2] Stoli? I, et al. Synthesis, DNA/RNA affinity and antitumour activity of new aromatic diamidines linked by 3,4-ethylenedioxythiophene. Eur J Med Chem. 2011 Feb;46(2):743-55. DOI:10.1016/j.ejmech.2010.12.010

HOECHST 33258 Preparation Products And Raw materials

Raw materials

Preparation Products

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HOECHST 33258 Suppliers

China 27 Europe 2 Japan 1 South Korea 1 United Kingdom 1 United States 8 Global 40

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
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Tianjin Kailiqi Biotechnology Co., Ltd.

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Heze Development Zone chuangli Chemical Co., Ltd.

Tel: 0530-+86-530-529 6766，+86-15666160102 15666160102
Fax: 0530-529 6766
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Musechem

Tel: +1-800-259-7612
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Aikon International Limited

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Yujinpharma(Tianjin) Technology Co.,Ltd.

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Shanghai Ze Chong Pharmaceutical Technology Co., Ltd.

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Email: sales@zechongchem.com
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Guangzhou Younan Technology Co., Ltd

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Changzhou Kechem Bio-Scientific Co., LTD.

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Shanghai kadel chemical technology co., LTD

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23491-44-3, HOECHST 33258Related Search:

Hoechst 33258 HOECHST 33258 Hoechst 33342 2'-(4-METHACRYLOXYPHENYL)-5-(4-METHYL-1-PIPER-AZINYL)-2,5'-BIBENZIMIDAZOLYL TRIHYDROCHLORIDE

2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE HYDRATE

BISBENZIMIDE H 33258

BISBENZIMIDE TRIHYDROCHLORIDE HYDRATE

CELLSTAIN- HOECHST 33258 SOLUTION

bisbenzimide trihydrochloride cell*culture tested

hoechst 33258 (bisbenzimide)

p-(5-(5-(4-methylpiperazin-1-yl)benzimidazol-2-yl)benzimidazol-2-yl)phenol

4-(5-(4-METHYL-1-PIPERAZINYL)(2,5''-BI-1H-BENZIMIDAZOL)2''-YL)PHENOL

bis-benzimide (hydroxyphenyl form)

Bisbenzimide,2-(4-hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5-bi-1H-benzimidazole,trihydrochloride

4-(5-(4-methyl-1-piperazinyl)(2,5’-bi-1h-benzimidazol)-2’-yl)-pheno

4-[6'-(4-Methylpiperazino)-6,2'-bi[1H-benzimidazole]-2-yl]phenol

4-[6-[6-(4-Methylpiperazino)-1H-benzimidazole-2-yl]-1H-benzimidazole-2-yl]phenol

Bisbenzimidazol

4-[5-(4-methyl-1-piperazinyl)[2,5’-bi-1h-benzimidazol]-2’-yl]-pheno

bisbenzimidazole

p-(5-(5-(4-methyl-1-piperazinyl)-2-benzimidazolyl)-2-benzimidazolyl)-pheno

pibenzimol

P-(5-(5-(4-METHYL-1-PIPERAZINYL)-2-BENZIMIDAZOLYL)-2-BENZIMIDAZOLYL)PHENOL

Phenol, 4-[5-(4-methyl-1-piperazinyl)[2,5'-bi-1H-benzimidazol]-2'-yl]-

4-(5-(4-Methylpiperazin-1-yl)-1H,1'H-[2,5'-bibenzo[d]imidazol]-2'-yl)phenol

23491-44-3

C25H24N6O

Cell Biology

Cell Signaling and Neuroscience

BioChemical

Apoptosis and Cell Cycle

Apoptosis Detection

Reagents