Lobetyolin

Product Name: Lobetyolin
CAS No.: 129277-38-9
Chemical Name: Lobetyolin
Synonyms: β-D-Glucopyranoside, (1R,2R,7E)-2-hydroxy-1-[(1E)-5-hydroxy-1-pentenyl]-7-nonene-3,5-diynyl (9CI)
CBNumber: CB24808608
Molecular Formula: C20H28O8
Formula Weight: 396.44
MOL File: 129277-38-9.mol

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Lobetyolin Property

Boiling point:: 698.5±55.0 °C(Predicted)
Density: 1.35±0.1 g/cm3(Predicted)
pka: 11.39±0.20(Predicted)
form: Solid
color: White to yellow
InChIKey: MMMUDYVKKPDZHS-FHMAEMBXNA-N
SMILES: O([C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@]([H])(/C=C/CCCO)[C@H](O)C#CC#C/C=C/C |&1:1,2,3,5,7,12,20,r|

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0008890
Product name: Lobetyolin
Purity: 99.89%
Packaging: 5mg
Price: $150
Updated: 2021/12/16

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Lobetyolin Chemical Properties,Usage,Production

Uses

Lobetyolin, a bioactive compound, is derived from Codonopsis pilosula. Lobetyolin has anti-inflammatory, anti-oxidative and xanthine oxidase inhibiting activities. Lobetyolin also induces the apoptosis via the inhibition of ASCT2-mediated glutamine metabolism[1][2]. Lobetyolin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

References

[1] Yoon YP, et al. Effects of Lobetyolin, Lobetyol and Methyl linoleate on Secretion, Production and Gene Expression of MUC5AC Mucin from Airway Epithelial Cells. Tuberc Respir Dis (Seoul). 2014 Nov;77(5):203-8. DOI:10.4046/trd.2014.77.5.203
[2] He W, et, al. Lobetyolin induces apoptosis of colon cancer cells by inhibiting glutamine metabolism. J Cell Mol Med. 2020 Mar;24(6):3359-3369. DOI:10.1111/jcmm.15009

Lobetyolin Preparation Products And Raw materials

Raw materials

Preparation Products

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129277-38-9, LobetyolinRelated Search:

Lobetyolin Lobetyolinin

β-D-Glucopyranoside, (1R,2R,7E)-2-hydroxy-1-[(1E)-5-hydroxy-1-pentenyl]-7-nonene-3,5-diynyl (9CI)

129277-38-9