BAY-545

Product Name: BAY-545
CAS No.: 1699717-32-2
Chemical Name: BAY-545
Synonyms: BAY-545;BAY-545, 10 mM in DMSO;BAY-545;BAY545;BAY 545;1699717-32-2;Inhibitor,BAY 545,BAY545,Adenosine Receptor,BAY-545,P1 receptor,inhibit;3-Ethyl-6-(4-hydroxypiperidine-1-carbonyl)-5-methyl-1-(3,3,3-trifluoropropyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione;Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, 3-ethyl-6-[(4-hydroxy-1-piperidinyl)carbonyl]-5-methyl-1-(3,3,3-trifluoropropyl)-
CBNumber: CB24819491
Molecular Formula: C18H22F3N3O4S
Formula Weight: 433.45
MOL File: 1699717-32-2.mol

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BAY-545 Property

Boiling point:: 598.7±60.0 °C(Predicted)
Density: 1.410±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:129.0(Max Conc. mg/mL);297.61(Max Conc. mM)
Ethanol:87.0(Max Conc. mg/mL);200.72(Max Conc. mM)
form: A solid
pka: 14.56±0.20(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28420
Product name: BAY-545
Packaging: 1mg
Price: $242
Updated: 2024/03/01

Cayman Chemical

Product number: 28420
Product name: BAY-545
Packaging: 5mg
Price: $1028
Updated: 2024/03/01

AK Scientific

Product number: 2270EF
Product name: 3-Ethyl-6-(4-hydroxypiperidine-1-carbonyl)-5-methyl-1-(3,3,3-trifluoropropyl)thieno[2,3-d]pyrimidine-2,4-dione
Packaging: 1mg
Price: $368
Updated: 2021/12/16

ChemScene

Product number: CS-0090874
Product name: BAY-545
Purity: 97.06%
Packaging: 5mg
Price: $450
Updated: 2021/12/16

ChemScene

Product number: CS-0090874
Product name: BAY-545
Purity: 97.06%
Packaging: 10mg
Price: $750
Updated: 2021/12/16

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BAY-545 Chemical Properties,Usage,Production

Uses

BAY-545 is a potent and selective A2B adenosine receptor antagonist, with an IC50 of 59 nM. BAY-545 also exhibits IC50s of 66, 400, 280 nM for human, mouse, rat A2B adenosine receptor in cells, respectively, and a Ki of 97 nM for human A2B adenosine receptor, with more selectivity over A1, A2A, and A3 adenosine receptor[1].

References

[1] H?rter M, et al. Novel non-xanthine antagonist of the A2B adenosine receptor: From HTS hit to lead structure. Eur J Med Chem. 2019 Feb 1;163:763-778. DOI:10.1016/j.ejmech.2018.11.045

BAY-545 Preparation Products And Raw materials

Raw materials

Preparation Products

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BAY-545 Suppliers

China 48 United States 5 Global 53

BOC Sciences

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ShangHai Caerulum Pharma Discovery Co., Ltd.

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Shanghai Lollane Biological Technology Co.,Ltd.

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TargetMol Chemicals Inc.

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1699717-32-2, BAY-545Related Search:

BAY-545

BAY-545;BAY545;BAY 545;1699717-32-2

Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, 3-ethyl-6-[(4-hydroxy-1-piperidinyl)carbonyl]-5-methyl-1-(3,3,3-trifluoropropyl)-

3-Ethyl-6-(4-hydroxypiperidine-1-carbonyl)-5-methyl-1-(3,3,3-trifluoropropyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione

Inhibitor,BAY 545,BAY545,Adenosine Receptor,BAY-545,P1 receptor,inhibit

BAY-545, 10 mM in DMSO

1699717-32-2