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RARECHEM AL BI 0212

Product Name
RARECHEM AL BI 0212
CAS No.
19064-14-3
Chemical Name
RARECHEM AL BI 0212
Synonyms
RARECHEM AL BI 0212;ETHYL 2,6-DIFLUOROBENZOATE;Ethyl 2,6-difluorobenzoate 97%;2,6-Difluorobenzoic acid, ethyl ester;Benzoic acid, 2,6-difluoro-, ethyl ester
CBNumber
CB2483616
Molecular Formula
C9H8F2O2
Formula Weight
186.16
MOL File
19064-14-3.mol
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RARECHEM AL BI 0212 Property

Boiling point:
228.0±30.0 °C(Predicted)
Density 
1.222±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
liquid
color 
Colourless
EPA Substance Registry System
Benzoic acid, 2,6-difluoro-, ethyl ester (19064-14-3)
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Safety

HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
E940113
Product name
Ethyl2,6-Difluorobenzoate
Packaging
100mg
Price
$90
Updated
2021/12/16
Matrix Scientific
Product number
083307
Product name
Ethyl 2,6-difluorobenzoate
Purity
97%
Packaging
1g
Price
$30
Updated
2021/12/16
AK Scientific
Product number
6423AD
Product name
Ethyl2,6-difluorobenzoate
Packaging
1g
Price
$38
Updated
2021/12/16
AK Scientific
Product number
J57038
Product name
Ethyl2,6-difluorobenzoate
Packaging
5g
Price
$95
Updated
2021/12/16
Apolloscientific
Product number
PC57044
Product name
Ethyl2,6-difluorobenzoate
Purity
97%
Packaging
5g
Price
$138
Updated
2021/12/16
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RARECHEM AL BI 0212 Chemical Properties,Usage,Production

Synthesis

372-18-9

109-94-4

437-81-0

19064-14-3

At -78 °C, n-butyllithium (n-BuLi, 1.67 M hexane solution, 1.32 mL, 2.2 mmol) was slowly added dropwise to a solution of tetrahydrofuran (THF, 3 mL) of 1,3-difluorobenzene (383 mg, 2.0 mmol), and the dropwise process was continued for 30 min. Subsequently, ethyl formate (1.6 mL, 20 mmol) was added to the reaction mixture and stirring was continued at -78 °C. After maintaining this temperature for 3 hours, iodine (I2, 1523 mg, 6 mmol), potassium carbonate (K2CO3, 1382 mg, 10 mmol), and ethanol (EtOH, 3 mL) were added to the reaction system, and then the mixture was warmed to room temperature and stirred for 14 hours. After completion of the reaction, the reaction was quenched with saturated aqueous sodium sulfite (Na2SO3) (5 mL) and extracted with chloroform (CHCl3, 3 x 20 mL). The organic layers were combined, washed with brine and dried over anhydrous sodium sulfate (Na2SO4) to give ethyl 2,6-difluorobenzoate in 77% yield. If necessary, the product can be purified by short column chromatography (silica gel (SiO2) as stationary phase, eluent is petroleum ether: ethyl acetate = 9:1) to obtain pure ethyl 2,6-difluorobenzoate in the form of colorless oil.

References

[1] Tetrahedron, 2012, vol. 68, # 24, p. 4701 - 4709

RARECHEM AL BI 0212 Preparation Products And Raw materials

Raw materials

Preparation Products

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RARECHEM AL BI 0212 Suppliers

Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
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61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2812
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65
Tianjin Jinyuda Chemical Co., Ltd.
Tel
022-58013646 13011382049
Fax
022-23854368
Email
sales@jinyudachem.com
Country
China
ProdList
1930
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55
Xinyanhe Pharmatech Co.,Ltd
Tel
0519-85252752 15366845260
Fax
86-0519-85683352
Email
taihuaren@vip.163.com
Country
China
ProdList
1125
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58
Changzhou Tianrui Pharmaceutical Technology Co., Ltd.
Tel
0519-85386832 13382812559
Fax
0519-85386832
Email
sales@cztrchem.com
Country
China
ProdList
1185
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Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
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58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
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58
Shanghai CR Corporation Limited
Tel
13062833949; 4006653949 4006653949
Fax
QQ: 2136646215
Email
fred.wen@crcorporation.cn
Country
China
ProdList
9758
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Aikon International Limited
Tel
025-58851090 15955137747
Fax
(6)02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15949
Advantage
58
Shanghai Shengli Biotech Co., Ltd.
Tel
021-62215214 13621821772
Fax
021-52261660
Email
3319226536@qq.com
Country
China
ProdList
910
Advantage
58
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View Lastest Price from RARECHEM AL BI 0212 manufacturers

Career Henan Chemica Co
Product
RARECHEM AL BI 0212 19064-14-3
Price
US $1.00/g
Min. Order
1g
Purity
85.0-99.8%
Supply Ability
20tons
Release date
2020-10-28