LIN28 inhibitor LI71
- Product Name
- LIN28 inhibitor LI71
- CAS No.
- 1357248-83-9
- Chemical Name
- LIN28 inhibitor LI71
- Synonyms
- Fdi 7;LIN28 inhibitor LI71;LIN28 inhibitor LI72;LIN28 inhibitor LI71, 10 mM in DMSO;LIN28 inhibitor LI71,MicroRNA,LIN-28 inhibitor LI71,inhibit,Inhibitor,miRNA;4-((3aS,4R,9bR)-6-Ethoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl)benzoic acid;Benzoic acid, 4-[(3aS,4R,9bR)-6-ethoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]-
- CBNumber
- CB24844985
- Molecular Formula
- C21H21NO3
- Formula Weight
- 335.4
- MOL File
- 1357248-83-9.mol
LIN28 inhibitor LI71 Property
- storage temp.
- 2-8°C(protect from light)
- solubility
- DMSO:100.0(Max Conc. mg/mL);298.15(Max Conc. mM)
- form
- Solid
- color
- Yellow to green
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CS-0087412
- Product name
- LIN28inhibitorLI71
- Purity
- 98.10%
- Packaging
- 5mg
- Price
- $420
- Updated
- 2021/12/16
- Product number
- CS-0087412
- Product name
- LIN28inhibitorLI71
- Purity
- 98.10%
- Packaging
- 10mg
- Price
- $700
- Updated
- 2021/12/16
- Product number
- CS-0087412
- Product name
- LIN28inhibitorLI71
- Purity
- 98.10%
- Packaging
- 50mg
- Price
- $2000
- Updated
- 2021/12/16
- Product number
- CS-0087412
- Product name
- LIN28inhibitorLI71
- Purity
- 98.10%
- Packaging
- 100mg
- Price
- $3000
- Updated
- 2021/12/16
- Product number
- A1273135
- Product name
- 4-((3aS,4R,9bR)-6-Ethoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl)benzoicacid
- Purity
- 98+%
- Packaging
- 5mg
- Price
- $390
- Updated
- 2021/12/16
LIN28 inhibitor LI71 Chemical Properties,Usage,Production
Uses
LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM. LIN28 inhibitor LI71 directly binds the cold shock domain (CSD) to suppress LIN28’s activity against let-7 in leukemia cells and embryonic stem cells[1].
References
[1] Wang L, et al. Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28. Cell Rep. 2018 Jun 5;23(10):3091-3101. DOI:10.1016/j.celrep.2018.04.116
LIN28 inhibitor LI71 Preparation Products And Raw materials
Raw materials
Preparation Products
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