Sulindac EP Impurity C-d3 (Sulindac Sulfide-d3)

Product Name: Sulindac EP Impurity C-d3 (Sulindac Sulfide-d3)
CAS No.: 250608-66-3
Chemical Name: Sulindac EP Impurity C-d3 (Sulindac Sulfide-d3)
Synonyms: D3-Sulindac Sulfide;SulindacEPImpurityC-d3;Sulindac EP Impurity C-d3 (Sulindac Sulfide-d3);Sulindac EP Impurity C-d3 (Sulindac USP Related Compound C-d3, Sulindac Sulfide-d3)
CBNumber: CB24849218
Molecular Formula: C20H17FO2S
Formula Weight: 340.41
MOL File: 250608-66-3.mol

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Hazard and Precautionary Statements (GHS)

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Sulindac EP Impurity C-d3 (Sulindac Sulfide-d3) Chemical Properties,Usage,Production

Uses

Sulindac sulfide-d3 is deuterium labeled Sulindac sulfide. Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC50 of 20.2 μM for γ42-secretase activity.

References

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Takahashi Y, et al. Sulindac sulfide is a noncompetitive gamma-secretase inhibitor that preferentially reduces Abeta 42 generation. J Biol Chem. 2003 May 16;278(20):18664-70. DOI:10.1074/jbc.M301619200

Sulindac EP Impurity C-d3 (Sulindac Sulfide-d3) Preparation Products And Raw materials

Raw materials

Preparation Products

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Sulindac EP Impurity C-d3 (Sulindac Sulfide-d3) Suppliers

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250608-66-3, Sulindac EP Impurity C-d3 (Sulindac Sulfide-d3)Related Search:

Sulindac EP Impurity C-d3 (Sulindac Sulfide-d3)

SulindacEPImpurityC-d3

Sulindac EP Impurity C-d3 (Sulindac USP Related Compound C-d3, Sulindac Sulfide-d3)

D3-Sulindac Sulfide

250608-66-3