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Ac4GlcNAl

Product Name
Ac4GlcNAl
CAS No.
1361993-37-4
Chemical Name
Ac4GlcNAl
Synonyms
Ac4GlcAl;Ac4GlcNAI;Ac4GlcNAl;Ac4GlcNAlk;N-(4-pentynoyl)-glucosamine tetraacylated;N-(4-pentynoyl)-glucosamine-tetraacylated (Ac4GlcAl);N-(4-pentynoyl)-glucosamine tetraacylated (Ac4GlcNAl) (CCT-1155);1,3,4,6-Tetra-O-acetyl-2-(4-pentynoylamino)-2-deoxy-D-glucopyranose;2-deoxy-2-[(1-oxo-4-pentyn-1-yl)amino]-1,3,4,6-Tetraacetate-D-Glucopyranose;2-deoxy-2-[(1-oxo-4- pentyn-1-yl) amino] -2- deoxy-1,3,4,6-tetra-O- acetyl-D-glucopyranose
CBNumber
CB24849405
Molecular Formula
C19H25NO10
Formula Weight
427.4
MOL File
1361993-37-4.mol
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Ac4GlcNAl Property

Boiling point:
570.1±50.0 °C(Predicted)
Density 
1.28±0.1 g/cm3(Predicted)
solubility 
Soluble to 100 mM in DMSO
pka
12.63±0.70(Predicted)
Appearance
beige powder
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Chem-Impex
Product number
35136
Product name
N-(4-pentynoyl)-glucosaminetetraacylated(Ac4GlcNAl),≥90%
Purity
≥90%
Packaging
5MG
Price
$116.48
Updated
2021/12/16
BroadPharm
Product number
BP-24305
Product name
N-(4-pentynoyl)-glucosamine-tetraacylated(Ac4GlcAl)
Packaging
25mg
Price
$235
Updated
2021/12/16
Chem-Impex
Product number
35136
Product name
N-(4-pentynoyl)-glucosaminetetraacylated(Ac4GlcNAl),90%
Purity
90%
Packaging
25MG
Price
$280
Updated
2021/12/16
Chem-Impex
Product number
35136
Product name
N-(4-pentynoyl)-glucosaminetetraacylated(Ac4GlcNAl),90%
Purity
90%
Packaging
100MG
Price
$750.4
Updated
2021/12/16
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Ac4GlcNAl Chemical Properties,Usage,Production

Description

Ac4GlcNAl is an unnatural alkyne-containing monosaccharide building block. The alkyne moiety can be used for modification though chemoselective ligation chemistries including CuAAC or various Pd-catalyzed coupling reactions. The acetyl groups increase solubility in many solvents and make handling of this reagent easier.

Uses

Ac4GlcNAlk is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

Alkyl-Chain

storage

Store at -20°C

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Ac4GlcNAl Preparation Products And Raw materials

Raw materials

Preparation Products

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Ac4GlcNAl Suppliers

Shanghai EFE Biological Technology Co., Ltd.
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View Lastest Price from Ac4GlcNAl manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Ac4GlcNAl 1361993-37-4
Price
US $0.00/mg
Min. Order
100mg
Purity
>95.00%
Supply Ability
100mg
Release date
2024-03-30
GlycoPharm.LLC
Product
Ac4GlcNAl 1361993-37-4
Price
US $0.00/mg
Min. Order
10mg
Purity
97%HPLC
Supply Ability
MG-KG
Release date
2020-03-17

1361993-37-4, Ac4GlcNAlRelated Search:


  • Ac4GlcNAl
  • 2-deoxy-2-[(1-oxo-4-pentyn-1-yl)amino]-1,3,4,6-Tetraacetate-D-Glucopyranose
  • 2-deoxy-2-[(1-oxo-4- pentyn-1-yl) amino] -2- deoxy-1,3,4,6-tetra-O- acetyl-D-glucopyranose
  • Ac4GlcNAlk
  • N-(4-pentynoyl)-glucosamine-tetraacylated (Ac4GlcAl)
  • Ac4GlcNAI
  • N-(4-pentynoyl)-glucosamine tetraacylated
  • 1,3,4,6-Tetra-O-acetyl-2-(4-pentynoylamino)-2-deoxy-D-glucopyranose
  • Ac4GlcAl
  • (3R,4R,5S,6R)-6-(Acetoxymethyl)-3-(pent-4-ynamido)tetrahydro-2H-pyran-2,4,5-triyl triacetate
  • N-(4-pentynoyl)-glucosamine tetraacylated (Ac4GlcNAl) (CCT-1155)
  • 1361993-37-4