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Amino-Tri-(carboxyethoxymethyl)-methane

Product Name
Amino-Tri-(carboxyethoxymethyl)-methane
CAS No.
174362-95-9
Chemical Name
Amino-Tri-(carboxyethoxymethyl)-methane
Synonyms
Amino-Tri-(carboxyethoxymethyl)-methane;Tri[(2-carboxyethoxy)methyl](amino)methane;Amino-Tri-(carboxyethoxymethyl)-methane (HCl);Amino-Tri-(carboxyethoxymethyl)-methane, TFA salt;3,3'-((2-amino-2-((2-carboxyethoxy)methyl)propane-1,3-diyl)bis(oxy))dipropionic acid;3,3’-[[2-Amino-2-[(2-carboxyethoxy)methyl]propane-1,3-diyl]bis(oxy)]dipropanoic Acid;Propanoic acid, 3,3'-[[2-amino-2-[(2-carboxyethoxy)methyl]-1,3-propanediyl]bis(oxy)]bis-
CBNumber
CB24849531
Molecular Formula
C13H23NO9
Formula Weight
337.32
MOL File
174362-95-9.mol
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Amino-Tri-(carboxyethoxymethyl)-methane Property

Boiling point:
620.2±55.0 °C(Predicted)
Density 
1.350±0.06 g/cm3(Predicted)
storage temp. 
2-8°C, protect from light
solubility 
Soluble in Water, DMSO, DCM, DMF
form 
low melting solid
pka
3.74±0.10(Predicted)
color 
Colourless
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23952
Product name
Amino-Tri-(carboxyethoxymethyl)-methane
Purity
98%
Packaging
100mg
Price
$320
Updated
2021/12/16
BroadPharm
Product number
BP-23952
Product name
Amino-Tri-(carboxyethoxymethyl)-methane
Purity
98%
Packaging
250mg
Price
$560
Updated
2021/12/16
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Amino-Tri-(carboxyethoxymethyl)-methane Chemical Properties,Usage,Production

Description

Amino-Tri-(carboxyethoxymethyl)-methane is a branched molecule that is reactive towards carboxylic acids in the presence of HATU. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Biological Activity

Amino-Tri-(carboxyethoxymethyl)-methan is a cleavable PEG-based ADC linker that can be used to synthesize antibody drug conjugates (ADCs). It is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules.

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

target

Amino-Tri-(carboxyethoxymethyl)-methane Preparation Products And Raw materials

Raw materials

Preparation Products

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Amino-Tri-(carboxyethoxymethyl)-methane Suppliers

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View Lastest Price from Amino-Tri-(carboxyethoxymethyl)-methane manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Amino-Tri-(carboxyethoxymethyl)-methane 174362-95-9
Price
US $0.00/mg
Min. Order
500mg
Purity
>95.00%
Supply Ability
500mg
Release date
2024-03-28

174362-95-9, Amino-Tri-(carboxyethoxymethyl)-methaneRelated Search:


  • Amino-Tri-(carboxyethoxymethyl)-methane
  • Tri[(2-carboxyethoxy)methyl](amino)methane
  • 3,3'-((2-amino-2-((2-carboxyethoxy)methyl)propane-1,3-diyl)bis(oxy))dipropionic acid
  • Amino-Tri-(carboxyethoxymethyl)-methane (HCl)
  • Propanoic acid, 3,3'-[[2-amino-2-[(2-carboxyethoxy)methyl]-1,3-propanediyl]bis(oxy)]bis-
  • 3,3’-[[2-Amino-2-[(2-carboxyethoxy)methyl]propane-1,3-diyl]bis(oxy)]dipropanoic Acid
  • Amino-Tri-(carboxyethoxymethyl)-methane, TFA salt
  • 174362-95-9
  • GalNAc

    • PEGs

    Cleavable