Methyltetrazine-PEG5-triethoxysilane

Product Name: Methyltetrazine-PEG5-triethoxysilane
CAS No.: 2353410-01-0
Chemical Name: Methyltetrazine-PEG5-triethoxysilane
Synonyms: Methyltetrazine-PEG5-triethoxysilane;N - (3-triethoxysilpropyl) octadecylamide;1-(4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenoxy)-N-(3-(triethoxysilyl)propyl)-3,6,9,12-tetraoxapentadecan-15-amide
CBNumber: CB24849612
Molecular Formula: C29H49N5O9Si
Formula Weight: 639.82
MOL File: 2353410-01-0.mol

More

Less

Methyltetrazine-PEG5-triethoxysilane Property

solubility: Soluble in DMSO, DCM, DMF

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

BroadPharm

Product number: BP-24141
Product name: Methyltetrazine-PEG5-triethoxysilane
Purity: 98%
Packaging: 50mg
Price: $320
Updated: 2021/12/16

BroadPharm

Product number: BP-24141
Product name: Methyltetrazine-PEG5-triethoxysilane
Purity: 98%
Packaging: 250mg
Price: $1050
Updated: 2021/12/16

More

Less

Methyltetrazine-PEG5-triethoxysilane Chemical Properties,Usage,Production

Description

Methyltetrazine-PEG5-triethoxysilane is a click chemistry linker containing a triethoxysilane moiety and a methyltetrazine group. Triethoxysilane is commonly used for surface modifications. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The hydrophilic PEG chain increases the water solubility of a compound in aqueous media.

Uses

Methyltetrazine-PEG5-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Methyltetrazine-PEG5-triethoxysilane Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Methyltetrazine-PEG5-triethoxysilane Suppliers

China 17 United States 4 Global 21

Henan's chemical products co., LTD

Tel: 0371-60919097 15378766539
Fax: 0371-60919097
Email: 794449696@qq.com
Country: China
ProdList: 4996
Advantage: 58

Alfa Chemistry

Tel: +1-5166625404;
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
Country: United States
ProdList: 20405
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

HUNAN CHEMFISH SCIENTIFIC CO.,LTD

Tel: +86-0731-85567275 13298656710
Fax: QQ:3554193828
Email: sales05@chemfish.com
Country: China
ProdList: 7449
Advantage: 58

Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

Tel: 13892832556
Email: 2440688701@qq.com
Country: China
ProdList: 1994
Advantage: 58

Zhengzhou Akem Chemical Co., Ltd

Tel: 13303867194
Email: 3001317055@qq.com
Country: China
ProdList: 9682
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 62220
Advantage: 58

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-80514535 19917294565
Email: et@chemextension.com
Country: China
ProdList: 5061
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

2353410-01-0, Methyltetrazine-PEG5-triethoxysilaneRelated Search:

Methyltetrazine-PEG5-triethoxysilane

1-(4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenoxy)-N-(3-(triethoxysilyl)propyl)-3,6,9,12-tetraoxapentadecan-15-amide

N - (3-triethoxysilpropyl) octadecylamide

2353410-01-0