ChemicalBook > CAS DataBase List > 2-DIMETHYLAMINO-PYRIMIDINE-5-CARBALDEHYDE

2-DIMETHYLAMINO-PYRIMIDINE-5-CARBALDEHYDE

Product Name
2-DIMETHYLAMINO-PYRIMIDINE-5-CARBALDEHYDE
CAS No.
55551-49-0
Chemical Name
2-DIMETHYLAMINO-PYRIMIDINE-5-CARBALDEHYDE
Synonyms
ASISCHEM C63425;TIMTEC-BB SBB010324;CHEMBRDG-BB 4010270;2-DIMETHYLAMINO-PYRIMIDINE-5-CARBALDEHYDE;5-Pyrimidinecarboxaldehyde, 2-(dimethylamino)-;2-(N,N-DiMethylaMino)pyriMidine-5-carboxaldehyde;2-(dimethylamino)pyrimidine-5-carbaldehyde(SALTDATA: FREE);2-DIMETHYLAMINO-PYRIMIDINE-5-CARBALDEHYDE ISO 9001:2015 REACH
CBNumber
CB2490335
Molecular Formula
C7H9N3O
Formula Weight
151.17
MOL File
55551-49-0.mol
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2-DIMETHYLAMINO-PYRIMIDINE-5-CARBALDEHYDE Property

Melting point:
122-124 °C
Boiling point:
289.6±32.0 °C(Predicted)
Density 
1.204±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
solid
pka
2.27±0.10(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1S/C7H9N3O/c1-10(2)7-8-3-6(5-11)4-9-7/h3-5H,1-2H3
InChIKey
XBYXYDVSCMMJDT-UHFFFAOYSA-N
SMILES
C1(N(C)C)=NC=C(C=O)C=N1
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22-43
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CBR00347
Product name
2-(Dimethylamino)pyrimidine-5-carbaldehyde
Purity
Aldrich
Packaging
1g
Price
$320
Updated
2024/03/01
AK Scientific
Product number
Z0688
Product name
2-Dimethylamino-pyrimidine-5-carbaldehyde
Packaging
1g
Price
$184
Updated
2021/12/16
Apolloscientific
Product number
OR954195
Product name
2-(Dimethylamino)pyrimidine-5-carbaldehyde
Purity
95%
Packaging
1g
Price
$185
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
D10420
Product name
2-(N,N-Dimethylamino)pyrimidine-5-carboxaldehyde
Purity
98%
Packaging
5g
Price
$225
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
D10420
Product name
2-(N,N-Dimethylamino)pyrimidine-5-carboxaldehyde
Purity
98%
Packaging
1g
Price
$60
Updated
2021/12/16
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2-DIMETHYLAMINO-PYRIMIDINE-5-CARBALDEHYDE Chemical Properties,Usage,Production

Synthesis

933702-55-7

55551-49-0

General procedure for the synthesis of 2-dimethylaminopyrimidine-5-carbaldehyde from 2-chloropyrimidine-5-carbaldehyde: 2-chloropyrimidine-5-carbaldehyde (412 mg, 2.89 mmol) and triethylamine (Et3N, 482 μL, 3.47 mmol) were dissolved in dioxane (20 mL), followed by the addition of a solution of dimethylamine (Me2NH) in tetrahydrofuran (THF) (1.59 mL, 2.0 M, 3.18 mmol). The reaction mixture was stirred at room temperature for 1 h. After completion of the reaction, the reaction solution was filtered and the solid was washed with dioxane (5 mL). The filtrate was concentrated under vacuum to give 2-dimethylaminopyrimidine-5-carbaldehyde (427 mg, 97.7% yield) as a yellow solid. The product was analyzed by LC-MS (ES+) and showed a molecular ion peak [MH]+ of 152.2. HPLC analysis showed a retention time (Rt) of 4.14 min and a purity of 97.9%.

References

[1] Patent: US2015/258101, 2015, A1

2-DIMETHYLAMINO-PYRIMIDINE-5-CARBALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-DIMETHYLAMINO-PYRIMIDINE-5-CARBALDEHYDE Suppliers

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View Lastest Price from 2-DIMETHYLAMINO-PYRIMIDINE-5-CARBALDEHYDE manufacturers

Dideu Industries Group Limited
Product
2-DIMETHYLAMINO-PYRIMIDINE-5-CARBALDEHYDE 55551-49-0
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-13
Career Henan Chemical Co
Product
2-DIMETHYLAMINO-PYRIMIDINE-5-CARBALDEHYDE 55551-49-0
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-08