ChemicalBook > CAS DataBase List > 3-[4-(BENZYLOXY)PHENYL]ACRYLIC ACID

3-[4-(BENZYLOXY)PHENYL]ACRYLIC ACID

Product Name
3-[4-(BENZYLOXY)PHENYL]ACRYLIC ACID
CAS No.
6272-45-3
Chemical Name
3-[4-(BENZYLOXY)PHENYL]ACRYLIC ACID
Synonyms
RARECHEM BK HW 0174;4-BENZYLOXYCINNAMIC ACID;(E)-4-BENZYLOXYCINNAMIC ACID;3-[4-(Benzyloxy)Phenyl]AcrylicAci;3-[4-(BENZYLOXY)PHENYL]ACRYLIC ACID;(E)-3-(4-(Benzyloxy)phenyl)acrylic acid;(E)-3-[4-(BENZYLOXY)PHENYL]-2-PROPENOIC ACID;3-[4-(BENZYLOXY)PHENYL]ACRYLIC ACID USP/EP/BP;(2E)-3-(4-(benzyloxy)phenyl)prop-2-enoic acid;2-Propenoic acid, 3-[4-(phenylmethoxy)phenyl]-
CBNumber
CB2494580
Molecular Formula
C16H14O3
Formula Weight
254.28
MOL File
6272-45-3.mol
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3-[4-(BENZYLOXY)PHENYL]ACRYLIC ACID Property

Melting point:
206-208°C
Boiling point:
448.9±25.0 °C(Predicted)
Density 
1.212
pka
4.59±0.10(Predicted)
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Safety

HazardClass 
IRRITANT
HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S107263
Product name
3-(4-BENZYLOXY-PHENYL)-ACRYLIC ACID
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$30.7
Updated
2025/07/31
Sigma-Aldrich
Product number
S107263
Product name
3-(4-BENZYLOXY-PHENYL)-ACRYLIC ACID
Purity
AldrichCPR
Packaging
100MG
Price
$29.8
Updated
2024/03/01
TRC
Product number
B289153
Product name
(E)-3-(4-(Benzyloxy)phenyl)acrylicAcid
Packaging
50mg
Price
$60
Updated
2021/12/16
AK Scientific
Product number
W7475
Product name
(E)-3-(4-(Benzyloxy)phenyl)acrylicacid
Packaging
1g
Price
$70
Updated
2021/12/16
AK Scientific
Product number
W7475
Product name
(E)-3-(4-(Benzyloxy)phenyl)acrylicacid
Packaging
5g
Price
$104
Updated
2021/12/16
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3-[4-(BENZYLOXY)PHENYL]ACRYLIC ACID Chemical Properties,Usage,Production

Synthesis

7400-08-0

100-39-0

6272-45-3

GENERAL STEPS: To 4-hydroxycinnamic acid (7 g, 42.6 mmol) was added anhydrous ethanol (40 mL) and stirred until completely dissolved to form a clarified solution. Subsequently, benzyl bromide (15 g, 10.6 mL, 87.7 mmol) and aqueous sodium hydroxide (8.5 g, 212 mmol, dissolved in 40 mL of distilled water) were added sequentially and stirred for 5 minutes to ensure homogeneous mixing. The reaction mixture was placed in a reflux unit and refluxed continuously for 36 hours. The progress of the reaction was monitored by thin layer chromatography (TLC) and after confirming the complete conversion of 4-hydroxycinnamic acid, the reaction mixture was cooled in an ice bath. Subsequently, the cooled ethanol reaction mixture was slowly poured into a 1-liter beaker containing crushed ice and carefully acidified with 5N hydrochloric acid to the proper pH to induce precipitation of solid compounds. The precipitate was collected by filtration, washed with plenty of water to remove impurities and finally dried to give the white solid product (E)-3-(4-(benzyloxy)phenyl)acrylic acid (10.3 g, 95% yield).

References

[1] Tetrahedron Letters, 2016, vol. 57, # 30, p. 3371 - 3375

3-[4-(BENZYLOXY)PHENYL]ACRYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-[4-(BENZYLOXY)PHENYL]ACRYLIC ACID manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
3-[4-(Benzyloxy)Phenyl]Acrylic Acid 6272-45-3
Price
US $3.00-9.00/KG
Min. Order
0.01KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2025-06-20
Hebei Fengqiang Trading Co., LTD
Product
3-[4-(BENZYLOXY)PHENYL]ACRYLIC ACID 6272-45-3
Price
US $100.00/bag
Min. Order
1bag
Purity
99
Supply Ability
5000
Release date
2023-09-07
Hebei Fengqiang Trading Co., LTD
Product
3-[4-(BENZYLOXY)PHENYL]ACRYLIC ACID 6272-45-3
Price
US $100.00/bag
Min. Order
1bag
Purity
99
Supply Ability
5000
Release date
2023-09-07

6272-45-3, 3-[4-(BENZYLOXY)PHENYL]ACRYLIC ACIDRelated Search:


  • 3-[4-(BENZYLOXY)PHENYL]ACRYLIC ACID
  • (E)-4-BENZYLOXYCINNAMIC ACID
  • (E)-3-[4-(BENZYLOXY)PHENYL]-2-PROPENOIC ACID
  • RARECHEM BK HW 0174
  • (2E)-3-(4-(benzyloxy)phenyl)prop-2-enoic acid
  • 3-[4-(Benzyloxy)phenyl]acrylic acid, 3-[4-(Benzyloxy)phenyl]prop-2-enoic acid
  • (E)-3-(4-(Benzyloxy)phenyl)acrylic acid
  • 4-BENZYLOXYCINNAMIC ACID
  • 2-Propenoic acid, 3-[4-(phenylmethoxy)phenyl]-
  • 3-[4-(Benzyloxy)Phenyl]AcrylicAci
  • 3-[4-(BENZYLOXY)PHENYL]ACRYLIC ACID USP/EP/BP
  • 6272-45-3
  • Aromatic Cinnamic Acids, Esters and Derivatives