ChemicalBook > CAS DataBase List > O-DESMETHYLNAPROXEN

O-DESMETHYLNAPROXEN

Product Name
O-DESMETHYLNAPROXEN
CAS No.
52079-10-4
Chemical Name
O-DESMETHYLNAPROXEN
Synonyms
(S)-DESMETHYLPROXEN;Naproxen Impurity A;Naproxen O-Desmethyl;(S)-Desmethylnaproxen;(S)-6-Demethylnaproxen;Naproxen EP IMpurity A;(S)-O-Desmethyl Naproxen;(S)-6-O-Desmethylnaproxen;O-Desmethylnaproxen;(2S)-2-(6-Hydroxynaphthalen-2-yl)pr
CBNumber
CB2497389
Molecular Formula
C13H12O3
Formula Weight
216.23
MOL File
52079-10-4.mol
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O-DESMETHYLNAPROXEN Property

Melting point:
182-183 °C
Boiling point:
432.1±20.0 °C(Predicted)
Density 
1.297±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: soluble
form 
solid
pka
4.87±0.30(Predicted)
color 
white
BRN 
8838512
CAS DataBase Reference
52079-10-4
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Safety

Hazard Codes 
Xn,N
Risk Statements 
22-43-50/53
Safety Statements 
36/37-60-61
RIDADR 
UN 3077 9/PG 3
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
UC305
Product name
O-Desmethylnaproxen
Packaging
5mg
Price
$354.2
Updated
2025/07/31
Sigma-Aldrich
Product number
95114
Product name
O-Desmethylnaproxen
Purity
analytical standard
Packaging
25mg
Price
$273
Updated
2025/07/31
Sigma-Aldrich
Product number
UC305
Product name
O-Desmethylnaproxen
Packaging
10mg
Price
$908
Updated
2025/07/31
TRC
Product number
D292125
Product name
(S)-O-DesmethylNaproxen
Packaging
100mg
Price
$1295
Updated
2021/12/16
TRC
Product number
D292125
Product name
(S)-O-DesmethylNaproxen
Packaging
5mg
Price
$110
Updated
2021/12/16
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O-DESMETHYLNAPROXEN Chemical Properties,Usage,Production

Chemical Properties

Off-Whie to Pale Pink Solid

Uses

A metabolite of Naproxen

Uses

O-Desmethylnaproxen can be used for assaying naproxen metabolites.

Definition

ChEBI: A member of the class of naphthols that is naproxen in which the 6-methoxy group has been demethylated.

Biochem/physiol Actions

CYP2C9 metabolite of naproxen

O-DESMETHYLNAPROXEN Preparation Products And Raw materials

Raw materials

Preparation Products

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52079-10-4, O-DESMETHYLNAPROXENRelated Search:

Naproxen sodium Naproxen

  • Naproxen Impurity 1（Naproxen EP Impurity A）
  • (s)-6-hydroxy-α-methyl-2-naphthaleneacetic acid
  • (aS)-6-Hydroxy-α-methyl-2-naphthaleneacetic Acid
  • (S)-2-(6-Hydroxy-2-naphthyl)propionic Acid
  • (S)-6-Demethylnaproxen
  • (S)-6-O-Desmethylnaproxen
  • (S)-O-Desmethyl Naproxen
  • (aS)-6-Hydroxy-a-methyl-2-naphthaleneacetic Acid
  • (S)-6-Hydroxy-α-methyl-2-naphthaleneacetic acid, d-2-(6-Hydroxy-2-naphthyl)proprionic acid
  • Naproxen EP IMpurity A
  • (S)-2-(6-hydroxynaphthalen-2-yl)propanoic acid
  • Naproxen O-Desmethyl
  • (2S)-2-(6-Hydroxynaphthalen-2-yl)pr
  • Naproxen EP Impurity A (O-Desmethyl Naproxen)
  • 2-Naphthaleneacetic acid, 6-hydroxy-α-methyl-, (αS)-
  • (S)-Desmethylnaproxen
  • Naproxen EP Impurity A ((S)-6-Demethylnaproxen)
  • (S)-DESMETHYLPROXEN
  • Naproxen Impurity A
  • (2S)-2-(6-Hydroxynaphthalen-2-yl)propanoic Acid (O-Demethylnaproxen)
  • <i>O</i>-Desmethylnaproxen
  • O-Desmethyl Naproxen: (2S)-2-(6-Hydroxynaphthalen-2-yl)propanoic acid
  • 52079-10-4
  • 18327-78-2
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Chiral Reagents