2'-CHLORO-2-HYDROXY-4-METHYLBENZOPHEN& Property

Melting point:

107-109 °C(lit.)

Boiling point:

378.7±27.0 °C(Predicted)

Density 

1.270±0.06 g/cm3(Predicted)

pka

7.45±0.35(Predicted)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

2914500090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

2'-CHLORO-2-HYDROXY-4-METHYLBENZOPHEN& Chemical Properties,Usage,Production

Uses

2′-Chloro-2-hydroxy-4-methylbenzophenone may be used in the synthesis of (4-hydroxy-6-methyl-1,3-phenylene)bis[(2-chlorophenyl)methanone.

Definition

ChEBI: 2-chloro-2'-hydroxy-4'-methylbenzophenone is a member of benzophenones.

Preparation

Preparation by Fries rearrangement of m-cresyl o-chloro-benzoate,
? with polyphosphoric acid at 130° for 40 min (87%);
? with aluminium chloride between 120° and 160° for 2 h.