ChemicalBook > CAS DataBase List > Ceforanide

Ceforanide

Product Name
Ceforanide
CAS No.
60925-61-3
Chemical Name
Ceforanide
Synonyms
C06884;BL-S-786;Ceforanide;CEFORANIDE (200 MG);Antibiotic BL-S-786;Ceforanide USP/EP/BP;Ceforanide (1097807);2-(2,4-Dimethylphenyl)sulf;Bacterial,inhibit,Antibiotic,Inhibitor,Ceforanide;(6R,7R)-7-(2-(2-(Aminomethyl)phenyl)acetamido)-3-(((1-(carboxymethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CBNumber
CB2501637
Molecular Formula
C20H21N7O6S2
Formula Weight
519.55
MOL File
60925-61-3.mol
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Ceforanide Property

Melting point:
>150° (dec)
Density 
1.79±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
Aqueous Base (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
pka
2.52±0.10(Predicted)
form 
Solid
color 
White to Pale Brown
Stability:
Hygroscopic
InChIKey
SLAYUXIURFNXPG-CRAIPNDOSA-N
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Safety

HS Code 
2941906000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1097807
Product name
Ceforanide
Packaging
200mg
Price
$377
Updated
2024/03/01
TRC
Product number
C242930
Product name
Ceforanide
Packaging
50mg
Price
$275
Updated
2021/12/16
TRC
Product number
C242930
Product name
Ceforanide
Packaging
100mg
Price
$495
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
63540
Product name
Ceforanide
Packaging
100mg
Price
$1025
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA41015
Product name
(6R,7R)-7-[[2-[2-Aminomethyl)phenyl]acetyl]amino]-3-[[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Packaging
1g
Price
$290
Updated
2021/12/16
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Ceforanide Chemical Properties,Usage,Production

Description

Ceforanide is a second generation cephalosporin with good β-lactamase resistance. It has a serum half-life of about three hours, allowing twice-daily dosing.

Originator

Bristol (USA)

Uses

Ceforanide is a cephalosporin based antibiotic used in the sterilization in various medical procedures.

Uses

Cephalosporin antibiotic

Definition

ChEBI: A second-generation cephalosporin antibiotic with {[1-(carboxymethyl)-1H-tetrazol-5-yl]sulfanyl}methyl and 2-(aminomethyl)phenylacetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is effective against many col forms, including Escherichia coli, Klebsiella, Enterobacter and Proteus, and most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Ari ona species.

brand name

Precef (Apothecon).

Antimicrobial activity

A semisynthetic parenteral cephalosporin with activity broadly similar to that of cefalotin. Its activity in vitro is significantly reduced in the presence of serum. A 1 g intravenous dose achieves a concentration of c. 135 mg/L at the end of infusion. The response after 0.25, 0.5 and 1 g intravenous doses is essentially linear. A 1 g intramuscular dose produces mean peak values of around 70 mg/L. Plasma protein binding is around 85%.
It is almost entirely eliminated in the urine with a halflife of about 2.5 h, 80–95% being recovered in the first 12 h. The half-life is inversely related to renal function, rising to around 20 h when the creatinine clearance falls below 5 mL/min. About half the dose is removed by hemodialysis over 6 h.
It is generally well tolerated; phlebitis and pain at the site of injection are reported in some patients with occasional transient neutropenia and increased transaminase levels. It has been used principally for the treatment of infections due to Gram-positive cocci, including staphylococcal and streptococcal soft-tissue infections, but is no longer widely available.

Ceforanide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Ceforanide manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Ceforanide 60925-61-3
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%
Supply Ability
500 MT
Release date
2020-05-25
Career Henan Chemical Co
Product
Ceforanide 60925-61-3
Price
US $7.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2018-12-21

60925-61-3, CeforanideRelated Search:


  • CEFORANIDE (200 MG)
  • Ceforanide
  • (6R,7R)-7α-[[(2-Aminomethylphenyl)acetyl]amino]-3-[[[1-(carboxymethyl)-1H-tetrazol-5-yl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • Antibiotic BL-S-786
  • BL-S-786
  • C06884
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[2-[2-(aMinoMethyl)phenyl]acetyl]aMino]-3-[[[1-(carboxyMethyl)-1H-tetrazol-5-yl]thio]Methyl]-8-oxo-,(6R,7R)-
  • (6R,7R)-7-[[2-[2-(Aminomethyl)phenyl]acetyl]amino]-3-[[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 2-(2,4-Dimethylphenyl)sulf
  • Ceforanide USP/EP/BP
  • (6R,7R)-7-(2-(2-(Aminomethyl)phenyl)acetamido)-3-(((1-(carboxymethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • Ceforanide (1097807)
  • Bacterial,inhibit,Antibiotic,Inhibitor,Ceforanide
  • 60925-61-3
  • C20H21N7O6S2
  • Ceforanide