KENDOMYCIN
- Product Name
- KENDOMYCIN
- CAS No.
- 183202-73-5
- Chemical Name
- KENDOMYCIN
- Synonyms
- kendomycin from streptomyces violaceoruber;1,19:5,9-Diepoxybenzocyclooctadecen-3(5H)-one, 6,7,8,9,10,11,12,15,16,17,18,19-dodecahydro-4,7,19-trihydroxy-2,6,8,12,14,16,18-heptamethyl-, (5R,6R,7S,8R,9R,12S,13E,16S,18S,19S)-
- CBNumber
- CB2503707
- Molecular Formula
- C29H42O6
- Formula Weight
- 486.64
- MOL File
- 183202-73-5.mol
KENDOMYCIN Property
- Melting point:
- 236-240℃
- Boiling point:
- 678.5±55.0 °C(Predicted)
- Density
- 1.19±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- Soluble in DMSO
- form
- solid
- pka
- 8.53±0.70(Predicted)
- color
- Yellow
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- K1513
- Product name
- Kendomycin from Streptomyces violaceoruber
- Purity
- solid
- Packaging
- 100μg
- Price
- $261
- Updated
- 2023/01/07
- Product number
- 11037
- Product name
- Kendomycin
- Purity
- ≥98%
- Packaging
- 100μg
- Price
- $81
- Updated
- 2024/03/01
- Product number
- 11037
- Product name
- Kendomycin
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $219
- Updated
- 2024/03/01
- Product number
- K162503
- Product name
- Kendomycin
- Packaging
- 100μg
- Price
- $145
- Updated
- 2021/12/16
- Product number
- BVT-0001-C500
- Product name
- Kendomycin
- Purity
- ≥98%(HPLC)
- Packaging
- 500μg
- Price
- $140
- Updated
- 2021/12/16
KENDOMYCIN Chemical Properties,Usage,Production
Description
Kendomycin is a macrolide from Streptomyces which displays potent cytotoxicity against several carcinoma cell lines (GI50 < 100 nM). It also acts as an endothelin receptor antagonist and has antiosteoporotic activities. Certain effects are thought to be mediated through inhibition of proteasomal degradation of proteins.
Uses
Kendomycin is an unusual macrocyclic metabolite containing a rare quinone methide group. Kendomycin is a potent antibacterial agent against Gram positive and Gram negative bacteria, including MRSA strains, also displaying antitumour activity. Kendomycin is a potent endothelin receptor agonist and demonstrates antiosteoporotic activity.
Uses
Kendomycin is a broadly efficacious polyketide macrocycle antibiotic.
Definition
ChEBI: Kendomycin is a member of benzofurans.
storage
+4°C
References
[1] KEVIN B. BAHNCK Scott D R. Formal Synthesis of (?)-Kendomycin Featuring a Prins-Cyclization To Construct the Macrocycle[J]. Journal of the American Chemical Society, 2008, 130 39: 13177-13181. DOI: 10.1021/ja805187p
KENDOMYCIN Preparation Products And Raw materials
Raw materials
Preparation Products
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