1-(CYCLOPROPANECARBONYL)PIPERAZINE 97

Product Name: 1-(CYCLOPROPANECARBONYL)PIPERAZINE 97
CAS No.: 59878-57-8
Chemical Name: 1-(CYCLOPROPANECARBONYL)PIPERAZINE 97
Synonyms: Cyclopropyl(piperazin-1-yl)methan-1-one hydrochloride;yl]-benzonitrile;Cyclopropanecarbonyl piperazine;N-(Cyclopropylcarbonyl)piperazine;1-(Cyclopropylcarbonyl)-piperazin;1-(Cyclopropylcarbonyl)piperazine;1-(Cyclopropanecarbonyl)plperazine;Piperazine, 1-(cyclopropylcarbonyl)-;Methanone, cyclopropyl-1-piperazinyl-;1-(Cyclopropylcarbonyl)piperazine, 97%
CBNumber: CB2505428
Molecular Formula: C8H14N2O
Formula Weight: 154.21
MOL File: 59878-57-8.mol

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1-(CYCLOPROPANECARBONYL)PIPERAZINE 97 Property

Boiling point:: 120 °C/0.15 mmHg
Density: 1.087 g/mL at 25 °C
refractive index: n20/D 1.524
Flash point:: >230 °F
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 8.47±0.10(Predicted)
form: Liquid
color: Colorless to pale brown
InChI: InChI=1S/C8H14N2O/c11-8(7-1-2-7)10-5-3-9-4-6-10/h7,9H,1-6H2
InChIKey: WIHDAPMHNYYTOA-UHFFFAOYSA-N
SMILES: C(C1CC1)(N1CCNCC1)=O

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Safety

Hazard Codes: Xi
Risk Statements: 37/38-41
Safety Statements: 26-36/37/39
WGK Germany: 2
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 653314
Product name: 1-(Cyclopropylcarbonyl)piperazine
Purity: 97%
Packaging: 1g
Price: $73
Updated: 2023/06/20

Sigma-Aldrich

Product number: 653314
Product name: 1-(Cyclopropylcarbonyl)piperazine
Purity: 97%
Packaging: 5g
Price: $276
Updated: 2023/06/20

TCI Chemical

Product number: C3850
Product name: Cyclopropyl(piperazin-1-yl)methanone
Purity: min. 98.0 %
Packaging: 1G
Price: $36
Updated: 2025/07/31

TCI Chemical

Product number: C3850
Product name: Cyclopropyl(piperazin-1-yl)methanone
Purity: min. 98.0 %
Packaging: 5G
Price: $108
Updated: 2025/07/31

TRC

Product number: C986680
Product name: 1-(Cyclopropylcarbonyl)piperazine
Packaging: 25mg
Price: $45
Updated: 2021/12/16

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1-(CYCLOPROPANECARBONYL)PIPERAZINE 97 Chemical Properties,Usage,Production

Uses

1-(Cyclopropylcarbonyl)piperazine

Synthesis

414910-15-9

59878-57-8

The general procedure for the synthesis of 1-cyclopropanecarbonylpiperazine from tert-butyl 4-(cyclopropanecarbonyl)piperazine-1-carboxylate was as follows: 1-tert-butoxycarbonyl-4-(cyclopropanecarbonyl)piperazine (190 mg, 0.75 mmol) was dissolved in dichloromethane (5 mL), followed by slow addition of trifluoroacetic acid (1 mL). The reaction mixture was stirred at room temperature and the progress of the reaction was monitored by thin layer chromatography (TLC) until complete consumption of the ingredients. Upon completion of the reaction, the reaction mixture was washed with saturated sodium bicarbonate solution (3 × 10 mL) to neutralize the acid. The organic phase was separated, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford 112 mg (97% yield) of 1-cyclopropanecarbonylpiperazine as a light yellow solid, which was used directly in the next step of the reaction.

References

[1] Patent: EP2799435, 2014, A1. Location in patent: Paragraph 0094
[2] Patent: US2015/51211, 2015, A1. Location in patent: Paragraph 0121
[3] Patent: US2004/14770, 2004, A1. Location in patent: Page/Page column 11
[4] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 16, p. 3739 - 3743

1-(CYCLOPROPANECARBONYL)PIPERAZINE 97 Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(CYCLOPROPANECARBONYL)PIPERAZINE 97 Suppliers

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View Lastest Price from 1-(CYCLOPROPANECARBONYL)PIPERAZINE 97 manufacturers

Jinan Ruitong Biotech Co., Ltd.

Product: 1-(Cyclopropylcarbonyl)piperazine 59878-57-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1
Release date: 2025-08-28

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 1-(CYCLOPROPANECARBONYL)PIPERAZINE 97 59878-57-8
Price: US $65.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000kg/week
Release date: 2024-06-05

Shaanxi Dideu New Materials Co. Ltd

Product: 1-(CYCLOPROPANECARBONYL)PIPERAZINE 97 59878-57-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-03-07

59878-57-8, 1-(CYCLOPROPANECARBONYL)PIPERAZINE 97Related Search:

Piperazine, 1-(cyclopropylcarbonyl)-, Monohydrochloride 1-(CYCLOPROPANECARBONYL)PIPERAZINE 97 2-((4-(5-(TRIFLUOROMETHYL)-2-PYRIDYL)PIPERAZINYL)CARBONYL)CYCLOPROPANECARBOXYLIC ACID [4-(1,3-BENZOTHIAZOL-2-YL)PIPERAZINO](CYCLOPROPYL)METHANONE 3-((4-[4-(CYCLOPROPYLCARBONYL)PIPERAZIN-1-YL]PIPERIDIN-1-YL)METHYL)BENZONITRILE HYDROCHLORIDE 7-BENZYL-1,3-DIMETHYL-8-[4-(CYCLOPROPYLCARBONYL)PIPERAZIN-1-YL]-3,7-DIHYDRO-1H-PURINE-2,6-DIONE 4-(3-CHLORO-5-(TRIFLUOROMETHYL)(2-PYRIDYL))PIPERAZINYL CYCLOPROPYL KETONE Piperazine, 1-(2-methylphenyl)-4-((2-(phenoxymethyl)cyclopropyl)carbon yl)-, trans- 2-((4-(5-CHLORO-2-METHYLPHENYL)PIPERAZINYL)CARBONYL)CYCLOPROPANECARBOXYLIC ACID 4-(3-CHLORO-5-(TRIFLUOROMETHYL)(2-PYRIDYL))PIPERAZINYL 2-PHENYLCYCLOPROPYL KETONE 8-[4-(CYCLOPROPYLCARBONYL)PIPERAZIN-1-YL]-1,3-DIMETHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE 1-Cyclopropylcarbonyl-4-phenylpiperazine hydrochloride 2-(4-[4-(CYCLOPROPYLCARBONYL)PIPERAZIN-1-YL]PIPERIDIN-1-YL)-4,6-DIMETHYLPYRIMIDINE HYDROCHLORIDE 1-(CYCLOPROPYLCARBONYL)-N-METHYL-4-[2-(PHENYLSULFONYL)ETHYL]PIPERAZINE-2-CARBOXAMIDE 2-((4-PHENYLPIPERAZINYL)CARBONYL)CYCLOPROPANECARBOXYLIC ACID Piperazine, 1-((2-(phenoxymethyl)cyclopropyl)carbonyl)-4-phenyl-, mono hydrochloride, trans- 1-[(2-METHYLCYCLOPROPYL)CARBONYL]PIPERAZINE 1-(CYCLOPROPYLCARBONYL)-4-(1-[2-(METHYLSULFONYL)BENZYL]PIPERIDIN-4-YL)PIPERAZINE HYDROCHLORIDE

1-(CYCLOPROPANECARBONYL)PIPERAZINE 97

1-(Cyclopropylcarbonyl)piperazine, 97%

Piperazine, 1-(cyclopropylcarbonyl)- (9CI)

1-(Cyclopropylcarbonyl)piperazine hydrochloride 97%

Cyclopropyl(piperazin-1-yl)methan-1-one hydrochloride

Piperazine, 1-(cyclopropylcarbonyl)-

N-(Cyclopropylcarbonyl)piperazine

1-(Cyclopropylcarbonyl)piperazine, 97% colorless to pale brown liquid

yl]-benzonitrile

Methanone, cyclopropyl-1-piperazinyl-

1-(CYCLOPROPANECARBONYL)PIPERAZINE 97 ISO 9001：2015 REACH

Cyclopropyl(piperazin-1-yl)methanone (Olaparib Impurity)

1-(Cyclopropylcarbonyl)-piperazin

1-(Cyclopropanecarbonyl)plperazine

Cyclopropyl-1-piperazinylmethanone as HCl

Cyclopropanecarbonyl piperazine

1-(Cyclopropylcarbonyl)piperazine

59878-57-8

29878-57-8

API intermediates

Building Blocks

Heterocyclic Building Blocks

Piperazines

Acids and Derivatives

Amines and Anilines

PIPERIDINE

59878-57-8

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