NAPHTHOQUINE PHOSPHATE

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NAPHTHOQUINE PHOSPHATE

Product Name: NAPHTHOQUINE PHOSPHATE
CAS No.: 173531-58-3
Chemical Name: NAPHTHOQUINE PHOSPHATE
Synonyms: NAPHTHOQUINE PHOSPHATE;Naphathoquine Phosphate;NAPHTHOQUINE PHOSPHATE USP/EP/BP;Naphthalene phosphoric acid phenol quinoline;4-[(7-Chloro-4-quinolinyl)amino]-2-[[(tert-butyl)amino]methyl]-5,6,7,8-tetrahydro-1-naphthalenol phosphate
CBNumber: CB2517511
Molecular Formula: C24H31ClN3O5P
Formula Weight: 507.95
MOL File: 173531-58-3.mol

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NAPHTHOQUINE PHOSPHATE Property

storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Soluble in DMSO
form: Powder

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology

Product number: A3641
Product name: Naphthoquinephosphate
Packaging: 10mg
Price: $61
Updated: 2021/12/16

ChemScene

Product number: CS-0739
Product name: Naphthoquine(phosphate)
Purity: 99.71%
Packaging: 10mg
Price: $72
Updated: 2021/12/16

ChemScene

Product number: CS-0739
Product name: Naphthoquine(phosphate)
Purity: 99.71%
Packaging: 50mg
Price: $120
Updated: 2021/12/16

ChemScene

Product number: CS-0739
Product name: Naphthoquine(phosphate)
Purity: 99.71%
Packaging: 100mg
Price: $180
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611920
Product name: Naphthoquine phosphate
Packaging: 50mg
Price: $229.5
Updated: 2021/12/16

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NAPHTHOQUINE PHOSPHATE Chemical Properties,Usage,Production

Biological Activity

malaria remains a disease of devastating global impact, killing more than 800,000 people every year-the vast majority being children under the age of 5. naphthoquine phosphate is a antimalarial drug developed in china.

in vitro

naphthoquine phosphate showed promising antimalaria acitivities against various p. falciparum strains. moreover, previoius study highlighted that naphthoquine did not lose potency when tested against chloroquine resistant strains [1].

in vivo

in an study aiming to investigate the antimalarial activity of naphthoquine phosphate combined with artemisinine against plasmodium knowlesi in rhesus monkey, it was found that the combination of naphthoquine phosphate and artemisinine was superior to the single component and the optimum proportion in the combination is 1 : 2.5 in treating p. knowlesi infection in monkeys [2].

target

malaria

IC 50

0.1-5.2 nm for various p. falciparum strains [1]

References

[1] delves m, plouffe d, scheurer c, meister s, wittlin s, winzeler ea, sinden re, leroy d. the activities of current antimalarial drugs on the life cycle stages of plasmodium: a comparative study with human and rodent parasites. plos med. 2012;9(2):e1001169.
[2] wang jy, ding db, li gf, zhao jh. therapeutic efficacy of naphthoquine phosphate combined with artemisinine against plasmodium knowlesi. zhongguo ji sheng chong xue yu ji sheng chong bing za zhi. 2008;26(6):442-4.
[3] tun t, tint hs, lin k, kyaw tt, myint mk, khaing w, tun zw. efficacy of oral single dose therapy with artemisinin-naphthoquine phosphate in uncomplicated falciparum malaria. acta trop. 2009;111(3):275-8.

NAPHTHOQUINE PHOSPHATE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from NAPHTHOQUINE PHOSPHATE manufacturers

Hebei Mojin Biotechnology Co., Ltd

Product: NAPHTHOQUINE PHOSPHATE 173531-58-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-08-31

Hebei Guanlang Biotechnology Co., Ltd.

Product: NAPHTHOQUINE PHOSPHATE 173531-58-3
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2021-08-30

Dideu Industries Group Limited

Product: NAPHTHOQUINE PHOSPHATE 173531-58-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-06-17

173531-58-3, NAPHTHOQUINE PHOSPHATERelated Search:

NAPHTHOQUINE PHOSPHATE

Naphthalene phosphoric acid phenol quinoline

Naphathoquine Phosphate

4-[(7-Chloro-4-quinolinyl)amino]-2-[[(tert-butyl)amino]methyl]-5,6,7,8-tetrahydro-1-naphthalenol phosphate

NAPHTHOQUINE PHOSPHATE USP/EP/BP

173531-58-3

C24H28ClN3O2H3O4P

C24H34ClN3O9P2