ChemicalBook > CAS DataBase List > Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester

Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester

Product Name: Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester
CAS No.: 843666-34-2
Chemical Name: Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester
Synonyms: Boc-C18-NHS ester;Boc-C16-NHS ester;SemaglutideImpurity7;t-butyl-octadecanedioate-NHS ester;1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester;1-tert-Butyl 18-(2,5-Dioxo-1-pyrrolidinyl) Octadecanedioate;1-tert-Butyl 18-(2,5-dioxopyrrolidin-1-yl) octadecanedioate;Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester;Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester（Boc-C16-NHS ester ）
CBNumber: CB25491216
Molecular Formula: C26H45NO6
Formula Weight: 467.64
MOL File: 843666-34-2.mol

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Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester Property

Boiling point:: 537.7±42.0 °C(Predicted)
Density: 1.05±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
form: Solid
color: White to off-white
InChI: InChI=1S/C26H45NO6/c1-26(2,3)32-24(30)18-16-14-12-10-8-6-4-5-7-9-11-13-15-17-19-25(31)33-27-22(28)20-21-23(27)29/h4-21H2,1-3H3
InChIKey: JTOVMMPSILRQQJ-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)CCCCCCCCCCCCCCCCC(ON1C(=O)CCC1=O)=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-24365
Product name: t-butyl-octadecanedioate-NHSester
Purity: 95%
Packaging: 500mg
Price: $280
Updated: 2021/12/16

BroadPharm

Product number: BP-24365
Product name: t-butyl-octadecanedioate-NHSester
Purity: 95%
Packaging: 1g
Price: $450
Updated: 2021/12/16

BroadPharm

Product number: BP-24365
Product name: t-butyl-octadecanedioate-NHSester
Purity: 95%
Packaging: 100mg
Price: $180
Updated: 2021/12/16

Ambeed

Product number: A899034
Product name: 1-tert-Butyl18-(2,5-dioxopyrrolidin-1-yl)octadecanedioate
Purity: 97%
Packaging: 250mg
Price: $220
Updated: 2021/12/16

Ambeed

Product number: A899034
Product name: 1-tert-Butyl18-(2,5-dioxopyrrolidin-1-yl)octadecanedioate
Purity: 97%
Packaging: 1g
Price: $536
Updated: 2021/12/16

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Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester Chemical Properties,Usage,Production

Description

t-butyl-octadecanedioate-NHS ester has a t-butyl ester group and an NHS ester moiety. The t-butyl group can be deprotected under acidic conditions. NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond.

Uses

Boc-C16-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester Preparation Products And Raw materials

Raw materials

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View Lastest Price from Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester manufacturers

Shanghai Joiny Pharmaceutical Co.,LTD

Product: Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester 843666-34-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2025-09-22

843666-34-2, Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) esterRelated Search:

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843666-34-2

C26H45NO6