ChemicalBook > CAS DataBase List > ONC206

ONC206

Product Name
ONC206
CAS No.
1638178-87-6
Chemical Name
ONC206
Synonyms
ONC206;TIC 260;ONC206, 10 mM in DMSO;ONC206; ONC-206; ONC 206.;7-Benzyl-4-(2,4-difluorobenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one;antagonist,Inhibitor,ONC201,DRD2/3/4,inhibit,receptors,D2-like,ONC206,Dopamine Receptor,dopamine,ONC-206,ONC 206;Imidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one, 4-[(2,4-difluorophenyl)methyl]-2,4,6,7,8,9-hexahydro-7-(phenylmethyl)-
CBNumber
CB25495926
Molecular Formula
C23H22F2N4O
Formula Weight
408.44
MOL File
1638178-87-6.mol
More
Less

ONC206 Property

Boiling point:
545.8±60.0 °C(Predicted)
Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 100 mg/mL (244.83 mM)
pka
6.21±0.20(Predicted)
form 
Solid
color 
Off-white to light yellow
InChI
InChI=1S/C23H22F2N4O/c24-18-7-6-17(20(25)12-18)14-29-22(30)19-15-27(13-16-4-2-1-3-5-16)10-8-21(19)28-11-9-26-23(28)29/h1-7,12H,8-11,13-15H2
InChIKey
ITMGVSSHWMTJRR-UHFFFAOYSA-N
SMILES
C12=NCCN1C1CCN(CC3=CC=CC=C3)CC=1C(=O)N2CC1=CC=C(F)C=C1F
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
36777
Product name
ONC206
Purity
≥98%
Packaging
5mg
Price
$50
Updated
2026/04/30
Cayman Chemical
Product number
36777
Product name
ONC206
Purity
≥98%
Packaging
10mg
Price
$95
Updated
2026/04/30
Cayman Chemical
Product number
36777
Product name
ONC206
Purity
≥98%
Packaging
25mg
Price
$161
Updated
2026/04/30
ChemScene
Product number
CS-0109614
Product name
ONC206
Purity
99.72%
Packaging
5mg
Price
$90
Updated
2021/12/16
ChemScene
Product number
CS-0109614
Product name
ONC206
Purity
99.72%
Packaging
10mg
Price
$150
Updated
2021/12/16
More
Less

ONC206 Chemical Properties,Usage,Production

Description

ONC206 is a derivative of the TRAIL-inducing compound TIC10 (Item No. 16109) with anticancer activity.1 It induces surface expression of TNF-related apoptosis-inducing ligand (TRAIL), apoptosis, and cell cycle arrest at the G1 phase in HCT116 cells when used at a concentration of 0.05 µM. ONC206 is cytotoxic to six patient-derived diffuse intrinsic pontine glioma (DIPG) cell lines (IC50s = 0.05-0.173 µM).2WARNING This product is not for human or veterinary use.

ONC206 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

ONC206 Suppliers

Shenzhen Yaoyuan R&D Center Co., Ltd
Tel
23284190 13421666688
Email
664261110@qq.com
Country
China
ProdList
60
Advantage
58
Shandong Mingde Biotechnology Co., Ltd.
Tel
18560864701
Email
2037956468@qq.com
Country
China
ProdList
779
Advantage
58
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
Tel
17702719238 18971495150;
Email
sales@sun-shinechem.com
Country
China
ProdList
1150
Advantage
64
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4827
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
89689
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
7999
Advantage
62
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9550
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
MQ (shanghai) Pharmaceuticals Co., Ltd.
Tel
13761635123
Fax
1014988033@qq
Email
sales@linyuepharm.com
Country
China
ProdList
5598
Advantage
55
More
Less

View Lastest Price from ONC206 manufacturers

Zhejiang J&C Biological Technology Co.,Limited
Product
ONC206 1638178-87-6
Price
US $0.00/gram
Min. Order
1gram
Purity
99%
Supply Ability
10kg
Release date
2022-02-18

1638178-87-6, ONC206Related Search:


  • ONC206
  • ONC206; ONC-206; ONC 206.
  • Imidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one, 4-[(2,4-difluorophenyl)methyl]-2,4,6,7,8,9-hexahydro-7-(phenylmethyl)-
  • TIC 260
  • antagonist,Inhibitor,ONC201,DRD2/3/4,inhibit,receptors,D2-like,ONC206,Dopamine Receptor,dopamine,ONC-206,ONC 206
  • 7-Benzyl-4-(2,4-difluorobenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one
  • ONC206, 10 mM in DMSO
  • 1638178-87-6
  • C23H22F2N4O
  • APIS
  • APL
  • APIs