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MAC glucuronide linker-2

Product Name
MAC glucuronide linker-2
CAS No.
229977-57-5
Chemical Name
MAC glucuronide linker-2
Synonyms
MAC glucuronide linker-2;Methyl 2-amino-4-(hydroxymethyl)phenyl β-D- glucopyranosiduronate 2,3,4-triacetate;2-Amino-4-(hydroxymethyl)phenyl methyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate;b-D-Glucopyranosiduronic acid, 2-amino-4-(hydroxymethyl)phenyl,methyl ester, 2,3,4-triacetate;β-D-Glucopyranosiduronic acid, 2-amino-4-(hydroxymethyl)phenyl, methyl ester, 2,3,4-triacetate;methyl (2S,3S,4S,5R,6S)-3,4,5-tris(acetyloxy)-6-(2-amino-4-(hydroxymethyl)phenoxy)oxepane-2-carboxylate;methyl (2S,3S,4S,5R,6S)-3,4,5-triacetoxy-6-[2-amino-4-(hydroxymethyl)phenoxy]tetrahydropyran-2-carboxylate;(2S,3R,4S,5S,6S)-2-[2-Amino-4-(hydroxymethyl)phenoxy]-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate;methyl (2S,3S,4S,5R,6S)-3,4,5-triacetoxy-6-[2-amino-4-(hydroxymethyl)phenoxy]tetrahydropyran-2-carboxylate - [M85411]
CBNumber
CB25821145
Molecular Formula
C20H25NO11
Formula Weight
455.41
MOL File
229977-57-5.mol
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MAC glucuronide linker-2 Property

Boiling point:
572.5±50.0 °C(Predicted)
Density 
1.39±0.1 g/cm3(Predicted)
form 
Solid
pka
14.27±0.10(Predicted)
color 
White to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical
Product number
M3763
Product name
MAC Glucuronide Linker-2
Packaging
100MG
Price
$150
Updated
2025/07/31
ChemScene
Product number
CS-0105172
Product name
MACglucuronidelinker-2
Purity
99.38%
Packaging
100mg
Price
$450
Updated
2021/12/16
ChemScene
Product number
CS-0105172
Product name
MACglucuronidelinker-2
Purity
99.38%
Packaging
500mg
Price
$1200
Updated
2021/12/16
ChemScene
Product number
CS-0105172
Product name
MACglucuronidelinker-2
Purity
99.38%
Packaging
1g
Price
$1800
Updated
2021/12/16
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MAC glucuronide linker-2 Chemical Properties,Usage,Production

Uses

MAC glucuronide linker-2 is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs). It contains a methylene alkoxycarbamate (MAC) self-destructive unit and can be used for the targeted delivery of alcohol-containing payloads to ADCs.

IC 50

Cleavable Linker; Glycosidase Cleavable Linker

MAC glucuronide linker-2 Preparation Products And Raw materials

Raw materials

Preparation Products

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229977-57-5, MAC glucuronide linker-2Related Search:


  • MAC glucuronide linker-2
  • (2S,3R,4S,5S,6S)-2-[2-Amino-4-(hydroxymethyl)phenoxy]-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate
  • β-D-Glucopyranosiduronic acid, 2-amino-4-(hydroxymethyl)phenyl, methyl ester, 2,3,4-triacetate
  • 2-Amino-4-(hydroxymethyl)phenyl methyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate
  • b-D-Glucopyranosiduronic acid, 2-amino-4-(hydroxymethyl)phenyl,methyl ester, 2,3,4-triacetate
  • methyl (2S,3S,4S,5R,6S)-3,4,5-triacetoxy-6-[2-amino-4-(hydroxymethyl)phenoxy]tetrahydropyran-2-carboxylate
  • methyl (2S,3S,4S,5R,6S)-3,4,5-tris(acetyloxy)-6-(2-amino-4-(hydroxymethyl)phenoxy)oxepane-2-carboxylate
  • Methyl 2-amino-4-(hydroxymethyl)phenyl β-D- glucopyranosiduronate 2,3,4-triacetate
  • methyl (2S,3S,4S,5R,6S)-3,4,5-triacetoxy-6-[2-amino-4-(hydroxymethyl)phenoxy]tetrahydropyran-2-carboxylate - [M85411]
  • 229977-57-5
  • C20H25NO11
  • ADC-Linker