ChemicalBook > CAS DataBase List > MD-224

MD-224

Product Name
MD-224
CAS No.
2136247-12-4
Chemical Name
MD-224
Synonyms
MD-224;MD-224, 10 mM in DMSO;11,E1/E2/E3 Enzyme,leukemia,PROTACs,E2 conjugating enzyme,MD 224;MD224,inhibit,PROTAC,Ubiquitin activating enzyme,Ubiquitin ligase,Inhibitor,MDM-2/p53,cancer,MD-224,E1 activating enzyme,Ubiquitin conjugating enzyme,E3 ligating enzyme,RS4;(3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-N-(4-((5-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)pent-4-yn-1-yl)carbamoyl)phenyl)-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamide;(3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-N-(4-((5-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)pent-4-yn-1-yl)carbamoyl)phenyl)-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamide , MD-224;Dispiro[cyclohexane-1,2'-pyrrolidine-3',3''-[3H]indole]-5'-carboxamide, 6''-chloro-4'-(3-chloro-2-fluorophenyl)-N-[4-[[[5-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-4-yl]-4-pentyn-1-yl]amino]carbonyl]phenyl]-1'',2''-dihydro-2''-oxo-, (3'R,4'S,5'R)-
CBNumber
CB25821231
Molecular Formula
C48H43Cl2FN6O6
Formula Weight
889.81
MOL File
2136247-12-4.mol
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MD-224 Property

Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:100.0(Max Conc. mg/mL);112.38(Max Conc. mM)
form 
Solid
pka
10.67±0.40(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0082057
Product name
MD-224
Purity
99.74%
Packaging
5mg
Price
$190
Updated
2021/12/16
ChemScene
Product number
CS-0082057
Product name
MD-224
Purity
99.74%
Packaging
10mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-0082057
Product name
MD-224
Purity
99.74%
Packaging
25mg
Price
$650
Updated
2021/12/16
ChemScene
Product number
CS-0082057
Product name
MD-224
Purity
99.74%
Packaging
50mg
Price
$950
Updated
2021/12/16
ChemScene
Product number
CS-0082057
Product name
MD-224
Purity
99.74%
Packaging
100mg
Price
$1750
Updated
2021/12/16

MD-224 Preparation Products And Raw materials

Raw materials

Preparation Products

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MD-224 Suppliers

ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185 18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3466
Advantage
58
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7787
Advantage
56
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4589
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
Jilin Province Woda Biotechnology Co., Ltd.
Tel
13504435624
Email
1927928688@qq.com
Country
China
ProdList
1467
Advantage
58
Wuxi Donghe Pharmaceutical Technology Co., Ltd.
Tel
63313187 15358055255
Fax
QQ:63313187
Email
63313187@qq.com
Country
China
ProdList
1987
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58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Absin Bioscience Inc.
Tel
021-38015121 15000105423
Email
wulan@absin.cn
Country
China
ProdList
24731
Advantage
58
ShangHai ChuanQian Chemcial Technique Centre
Tel
15869524721
Email
3525679403@qq.com
Country
China
ProdList
4343
Advantage
58
Zhengzhou convergence chemical co., LTD
Tel
0371-0371-55153829 18003835034
Fax
18003835034(微信)
Email
2853979819@qq.com
Country
China
ProdList
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Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
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Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
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62075
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58
InvivoChem
Tel
13549236410
Email
sales@invivochem.cn
Country
China
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TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
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Shanghai Yiyan Biotechnology Co. , Ltd.
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021-69985186 13611928337
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China
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Nantong QuanYi Biotechnology Co., Ltd
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0513-66337626 18051384581
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sales@chemhifuture.com
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China
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Shanghai Easy CDMO Co.,Ltd
Tel
021-61734564
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August@easycdmo.com
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China
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10030
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58
Nanjing Shizhou Biology Technology Co.,Ltd
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025-85560043 15850508050
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025-85563444
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cindy.huang@synzest.com
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China
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Jilin Chinese Academy of Sciences-yanshen Technology
Tel
18143011203
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ET-market@chemextension.com
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China
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RD International Technology Co., Limited
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18024082417
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market@ubiochem.com
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China
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Tel
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sangon@qq.com
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CHINA
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ATK CHEMICAL COMPANY LIMITED
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+undefined-21-51877795
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+86 21 5161 9052/ 5187 7796
Email
ivan@atkchemical.com
Country
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Absin Bioscience Inc.
Tel
--
Fax
--
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chenjw@absin.cn
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CHINA
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6705
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Proteintech China
Tel
--
Fax
--
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Proteintech-CN@ptglab.com
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CHINA
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Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
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Email
info@zzsrm.com
Country
CHINA
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6650
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2136247-12-4, MD-224Related Search:


  • MD-224
  • Dispiro[cyclohexane-1,2'-pyrrolidine-3',3''-[3H]indole]-5'-carboxamide, 6''-chloro-4'-(3-chloro-2-fluorophenyl)-N-[4-[[[5-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-4-yl]-4-pentyn-1-yl]amino]carbonyl]phenyl]-1'',2''-dihydro-2''-oxo-, (3'R,4'S,5'R)-
  • 11,E1/E2/E3 Enzyme,leukemia,PROTACs,E2 conjugating enzyme,MD 224
  • MD224,inhibit,PROTAC,Ubiquitin activating enzyme,Ubiquitin ligase,Inhibitor,MDM-2/p53,cancer,MD-224,E1 activating enzyme,Ubiquitin conjugating enzyme,E3 ligating enzyme,RS4
  • (3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-N-(4-((5-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)pent-4-yn-1-yl)carbamoyl)phenyl)-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamide , MD-224
  • (3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-N-(4-((5-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)pent-4-yn-1-yl)carbamoyl)phenyl)-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamide
  • MD-224, 10 mM in DMSO
  • 2136247-12-4
  • C48H43Cl2FN6O6