(S)-BAY-293

Product Name: (S)-BAY-293
CAS No.: 2244904-69-4
Chemical Name: (S)-BAY-293
Synonyms: BAY 294;(S)-BAY-293;BAY 293 Negative Control;4-Quinazolinamine, 6,7-dimethoxy-2-methyl-N-[(1S)-1-[4-[2-[(methylamino)methyl]phenyl]-2-thienyl]ethyl]-
CBNumber: CB25867497
Molecular Formula: C25H28N4O2S
Formula Weight: 448.58
MOL File: 2244904-69-4.mol

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(S)-BAY-293 Property

Boiling point:: 553.4±50.0 °C(Predicted)
Density: 1.218±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 9.61±0.10(Predicted)
form: Solid
color: White to off-white
optical activity: [α]/D +86.0 to +106.0°, c =1.0 in DMSO

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 6906
Product name: BAY293NegativeControl
Purity: ≥98%(HPLC)
Packaging: 5
Price: $235
Updated: 2021/12/16

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(S)-BAY-293 Chemical Properties,Usage,Production

Biological Activity

BAY-294 corresponds to the (S)-enantiomer of and the recommended control for the selective SOS1-KRAS interaction inhibitor BAY-293 (IC50 = 2.34 μM/BAY-294 vs. 21 nM/BAY-293; 10 nM hSOS1c at & 5 nM hKRAS G12C). BAY-294 exhibits little potency against SOS1-mediated KRAS activation (IC50 = 3.91 μM/BAY-294 vs. 52 nM/BAY-293; 10 nM SOS1c at & 50 nM wt hKRAS).

storage

Store at -20°C

(S)-BAY-293 Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-BAY-293 Suppliers

China 10 United States 1 Global 11

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2244904-69-4, (S)-BAY-293Related Search:

(S)-BAY-293

BAY 293 Negative Control

4-Quinazolinamine, 6,7-dimethoxy-2-methyl-N-[(1S)-1-[4-[2-[(methylamino)methyl]phenyl]-2-thienyl]ethyl]-

BAY 294

2244904-69-4