1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT

Product Name: 1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT
CAS No.: 1628353-02-5
Chemical Name: 1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT
Synonyms: PTDINS-(3,4,5)-P3 (1,2-DIPALMITOYL) SODIUM SALT;PHOSPHATIDYLINOSITOL-3,4,5-TRIPHOSPHATE C-16 SODIUM SALT;1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT
CBNumber: CB2675372
Molecular Formula: C41H83NaO22P4
Formula Weight: 1074.98
MOL File: Mol file

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1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT Property

storage temp.: Store at -20°C
solubility: CHCl3:CH3OH:H2O (2.5:3:1): 3.8 mg/ml; PBS (pH 7.2): 10 mg/ml
form: A lyophilized powder

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 64920
Product name: PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)
Purity: ≥98%
Packaging: 100μg
Price: $47
Updated: 2024/03/01

Cayman Chemical

Product number: 64920
Product name: PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)
Purity: ≥98%
Packaging: 500μg
Price: $206
Updated: 2024/03/01

Cayman Chemical

Product number: 64920
Product name: PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)
Purity: ≥98%
Packaging: 1mg
Price: $360
Updated: 2024/03/01

Cayman Chemical

Product number: 64920
Product name: PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)
Purity: ≥98%
Packaging: 5mg
Price: $1570
Updated: 2024/03/01

AK Scientific

Product number: 3144EL
Product name: Tetrasodium;[(1R,2S,4S,5S)-3-[[(2R)-2,3-di(hexadecanoyloxy)propoxy]-oxidophosphoryl]oxy-2,4-dihydroxy-5,6-bis[[hydroxy(oxido)phosphoryl]oxy]cyclohexyl]hydrogenphosphate
Packaging: 1mg
Price: $499
Updated: 2021/12/16

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1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT Chemical Properties,Usage,Production

Description

The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.^1,2 PtdIns-(3,4,5)-P₃ can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P₃-binding proteins.^3,4 Protein-binding to PtdIns-(3,4,5)-P₃ is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P₃ is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. For further reading on inositol phospholipids, see also references ⁵ and ⁶.

References

1. Lapetina, E.G., Billah, M.M., and Cuatrecasas, P. The phosphatidylinositol cycle and the regulation of arachidonic acid production Nature 292,367-369(1981).
2. Majerus, P.W. Inositol phosphate biochemistry Annu. Rev. Biochem. 61,225-250(1992).
3. Tanaka, K., Imajoh-Ohmi, S., Sawada, T., et al. A target of phosphatidylinositol 3,4,5-trisphosphate with a zinc finger motif similar to that of the ADP-ribosylation-factor GTPase-activating protein and two pleckstrin homology domains Eur. J. Biochem. 245,512-519(1997).
4. Yang, X., Rudolf, M., Carew, M.A., et al. Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate J. Biol. Chem. 274(27),18973-18980(1999).
5. Pike, L.J., and Casey, L. Localization and turnover of phosphatidylinositol 4,5-bisphosphate in caveolin-enriched membrane domains J. Biol. Chem. 271,26453-26456(1996).
6. Berridge, M.J. Inositol trisphosphate and calcium signalling Nature 361(6410),315-325(1993).

1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT Suppliers

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1628353-02-5, 1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALTRelated Search:

1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT

PHOSPHATIDYLINOSITOL-3,4,5-TRIPHOSPHATE C-16 SODIUM SALT

PTDINS-(3,4,5)-P3 (1,2-DIPALMITOYL) SODIUM SALT

1628353-02-5