4-CYANO-3-METHYLISOQUINOLINE

Product Name: 4-CYANO-3-METHYLISOQUINOLINE
CAS No.: 161468-32-2
Chemical Name: 4-CYANO-3-METHYLISOQUINOLINE
Synonyms: 4-CYANO-3-METHYLISOQUINOLINE;4-Isoquinolinecarbonitrile, 3-methyl-
CBNumber: CB2676157
Molecular Formula: C11H8N2
Formula Weight: 168.19
MOL File: Mol file

More

Less

4-CYANO-3-METHYLISOQUINOLINE Property

Boiling point:: 330.9±22.0 °C(Predicted)
Density: 1.17±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Soluble in DMSO (50mg/ml)
form: solid
pka: 2.26±0.31(Predicted)
color: white

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: PRK0000427
Product name: 4-CYANO-3-METHYLISOQUINOLINE
Purity: 95.00%
Packaging: 5MG
Price: $504.06
Updated: 2021/12/16

AccelPharmtech

Product number: D4708
Product name: 3-methyl-4-Isoquinolinecarbonitrile
Purity: 97.00%
Packaging: 1G
Price: $2280
Updated: 2021/12/16

More

Less

4-CYANO-3-METHYLISOQUINOLINE Chemical Properties,Usage,Production

Uses

4-Cyano-3-methylisoquinoline is an inhibitor for protein kinase A (PKA) with an IC50 of micromolar level. 4-Cyano-3-methylisoquinoline reverses morphine tolerance in mouse model[1].

Definition

ChEBI: 3-methyl-4-isoquinolinecarbonitrile is a member of isoquinolines.

Biological Activity

Cell permeable: yes', 'Primary Target
PKA', 'Product competes with ATP.', 'Reversible: yes', 'Target IC50: 30 nM against protein kinase A

storage

+4°C

References

[1] Smith FL, et al., The expression of a high level of morphine antinociceptive tolerance in mice involves both PKC and PKA. Brain Res. 2003 Sep 19;985(1):78-88. DOI:10.1016/s0006-8993(03)03170-6

4-CYANO-3-METHYLISOQUINOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-CYANO-3-METHYLISOQUINOLINE Suppliers

CHINA 13 United Kingdom 1 United States 3 Global 17

VDM Biochemicals

Tel: 0330-2528181
Fax: 0330-2528171
Email: sales@vdmbio.com
Country: United States
ProdList: 510
Advantage: 64

Henan Weitesi Chemical Technology Co. LTD

Tel: 0371-0371-55135753 18003832934
Fax: QQ：2853979818
Email: 2853979818@qq.com
Country: China
ProdList: 9991
Advantage: 58

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-80514535 19917294565
Email: ET-market@chemextension.com
Country: China
ProdList: 4673
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: 400-6206333 13167063860
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 48457
Advantage: 58

Merck Millipore

Tel: 1-400-889-1988 400-889-1988
Email: bioscience@merckgroup.com
Country: China
ProdList: 6839
Advantage: 58

Merck KGaA

Tel: 21-20338288
Email: ordercn@merckgroup.com
Country: China
ProdList: 6394
Advantage: 58

Santa Cruz Biotechnology Inc

Tel: 021-60936350
Email: scbt@scbt.com
Country: China
ProdList: 6594
Advantage: 58

DAYANG CHEM (HANGZHOU) CO.,LTD

Tel: +86-88938639 +86-17705817739
Email: info@dycnchem.com
Country: China
ProdList: 53899
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 52923
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: +undefined18143011203
Email: info@chemextension.com
Country: China
ProdList: 42056
Advantage: 58

161468-32-2, 4-CYANO-3-METHYLISOQUINOLINERelated Search:

4-CYANO-3-METHYLISOQUINOLINE

4-Isoquinolinecarbonitrile, 3-methyl-

161468-32-2

A potent, cell-permeable, reversible, and specific inhibitor of protein kinase A.