2-Thiothymidine

Product Name: 2-Thiothymidine
CAS No.: 28585-51-5
Chemical Name: 2-Thiothymidine
Synonyms: 2-THIOTHYMIDINE;Thymidine, 2-thio-;2-Thio-2'-deoxythymidine;2'-deoxy-5-methyl-2-thiouridine;1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone;1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one;1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one;1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one
CBNumber: CB2693213
Molecular Formula: C10H14N2O4S
Formula Weight: 258.29
MOL File: 28585-51-5.mol

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2-Thiothymidine Property

form: Solid
color: White to off-white
InChI: InChI=1S/C10H14N2O4S/c1-5-3-12(10(17)11-9(5)15)8-2-6(14)7(4-13)16-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,17)/t6-,7+,8+/m0/s1
InChIKey: PISWNSOQFZRVJK-XLPZGREQSA-N
SMILES: OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=S)C[C@@H]1O

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: T375288
Product name: 2-Thiothymidine
Packaging: 5mg
Price: $150
Updated: 2021/12/16

Usbiological

Product number: 296443
Product name: 2-Thiothymidine
Packaging: 10mg
Price: $359
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NT02914
Product name: 2-Thiothymidine
Packaging: 10mg
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NT02914
Product name: 2-Thiothymidine
Packaging: 25mg
Price: $125
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: NUC0003081
Product name: 2-THIOTHYMIDINE
Purity: 98.00%
Packaging: 10MG
Price: $173.25
Updated: 2021/12/16

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2-Thiothymidine Chemical Properties,Usage,Production

Uses

2-Thiothymidine is a mRNA therapy used for treatment of ornithine transcarbamylase deficiency.

Application

2-Thiothymidine is a hydrogen bond donor and acceptor that can be used as a substitute for thymine in the synthesis of DNA. 2-Thiothymidine has been shown to have successful in vivo treatment against bladder cancer and skin cells, as well as photochemical properties. It has been shown to inhibit the growth of prostate cancer cells by inhibiting DNA synthesis. 2-Thiothymidine binds to dna duplexes and polymerase chain reactions, which are important for replication of DNA. This drug also inhibits replication by preventing intramolecular hydrogen bonds from forming. 2-Thiothymidine is a nucleoside analog that is substituted for thymine during DNA synthesis. It inhibits the growth of prostate cancer cells by inhibiting DNA synthesis. It binds to dna duplexes and polymerase chain reactions, which are important for replication of DNA. This drug also inhibits replication by preventing intramolecular hydrogen bonds from forming.

Definition

2-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc

2-Thiothymidine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Thiothymidine Suppliers

China 31 India 1 United Kingdom 1 United States 8 Global 41

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28585-51-5, 2-ThiothymidineRelated Search:

Nucleoside 1-(2-HYDROXY-ETHOXYMETHYL)-2-THIOXO-2,3-DIHYDRO-1H-PYRIMIDIN-4-ONE 5-METHYL-2-THIOURIDINE 2-THIOTHYMIDINE-5'-TRIPHOSPHATE LITHIUM SALT 2-Thiothymidine

2'-deoxy-5-methyl-2-thiouridine

1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone

2-THIOTHYMIDINE

1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one

2-Thio-2'-deoxythymidine

Thymidine, 2-thio-

1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one

28585-51-5