TEBBE REAGENT
- Product Name
- TEBBE REAGENT
- CAS No.
- 67719-69-1
- Chemical Name
- TEBBE REAGENT
- Synonyms
- tebbe;Tebbe reag;TEBBE REAGENT;Tebbe's reagent;tebbe reagent solution;ca.0.5mol/lToluenesolution;Tebbe Reagent 0.5 M in Toluene;TEBBE REAGENT ISO 9001：2015 REACH;TEBBE REAGENT, 0.5M SOLUTION IN TOLUENE;Tebbe Reagent (ca. 0.5mol/L in Toluene)
- CBNumber
- CB2693440
- Molecular Formula
- C13H4AlClTi
- Formula Weight
- 270.47
- MOL File
- 67719-69-1.mol
TEBBE REAGENT Property
- Density
- 0.96 g/mL at 20 °C
- Flash point:
- 34 °F
- storage temp.
- Refrigerator
- form
- Solution
- color
- Dark red to purple
- Water Solubility
- Soluble in toluene, benzene, dichloromethane. Insoluble in water.
- Sensitive
- Air & Moisture Sensitive
- Merck
- 9091
- Exposure limits
- ACGIH: TWA 20 ppm
OSHA: Ceiling 300 ppm; TWA 200 ppm
NIOSH: IDLH 500 ppm; TWA 100 ppm(375 mg/m3); STEL 150 ppm(560 mg/m3) - InChIKey
- QEJAQNUJXFLWSP-UHFFFAOYSA-M
Safety
- Hazard Codes
- F,C
- Risk Statements
- 11-34-48/20-63-65-67
- Safety Statements
- 26-36/37/39-45-62-16
- RIDADR
- UN 2924 3/PG 2
- WGK Germany
- 2
- F
- 1-10
- HazardClass
- 4.3
- PackingGroup
- II
- HS Code
- 29310099
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H261In contact with water releases flammable gas
H302Harmful if swallowed
H304May be fatal if swallowed and enters airways
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H333May be harmful if inhaled
H336May cause drowsiness or dizziness
H361Suspected of damaging fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P223Keep away from any possible contact with water, because of violent reaction and possible flash fire.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 380237
- Product name
- Tebbe reagent solution
- Purity
- 0.5 M in toluene
- Packaging
- 25ml
- Price
- $296
- Updated
- 2024/03/01
- Product number
- 380237
- Product name
- Tebbe reagent solution
- Purity
- 0.5 M in toluene
- Packaging
- 4x25ml
- Price
- $482
- Updated
- 2024/03/01
- Product number
- 044506
- Product name
- μ-Chloro-μ-methylenebis(cyclopentadienyl)titaniumdimethylaluminum, 0.5M in toluene
- Packaging
- 5ml
- Price
- $74.7
- Updated
- 2024/03/01
- Product number
- 044506
- Product name
- μ-Chloro-μ-methylenebis(cyclopentadienyl)titaniumdimethylaluminum, 0.5M in toluene
- Packaging
- 25ml
- Price
- $296
- Updated
- 2024/03/01
- Product number
- 380237
- Product name
- Tebbe reagent solution
- Purity
- 0.5 M in toluene
- Packaging
- 100ml
- Price
- $1120
- Updated
- 2024/03/01
TEBBE REAGENT Chemical Properties,Usage,Production
Chemical Properties
Dark red to purple solution
Chemical Properties
The Tebbe reagent is the organometallic compound with the formula (CH)TiCHClAl(CH). It is used in the methylenation of carbonyl compounds, that is it converts organic compounds containing the RC=O group into the related RC=CH derivative.It is a red solid that is pyrophoric in the air, and thus is typically handled with air-free techniques. It was originally synthesized by Fred Tebbe at DuPont Central Research. Tebbe's reagent contains two tetrahedral metal centers linked by a pair of bridging ligands. The titanium has two cyclopentadienyl ([CH]-, or Cp) rings and aluminium has two methyl groups. The titanium and aluminium atoms are linked together by both a methylene bridge (-CH-) and a chloride atom in a nearly square-planar (Ti–CH–Al–Cl) geometry.The Tebbe reagent was the first reported compound where a methylene bridge connects a transition metal (Ti) and a main group metal (Al).Preparation The Tebbe reagent is synthesized from titanocene dichloride and trimethylaluminium in toluene solution.
Uses
μ-Chloro-μ-methylenebis(cyclopentadienyl)titaniumdimethylaluminum is used in organic synthesis for carbonyl methylenation, A versatile methylenation reagent for the conversion of ketones and aldehydes to olefins, it offers facile reaction with hindered ketones and allows the conversion of esters to vinyl ethers. Tebbe reagent can be used to olefinate aldehydes, to methylenate a chiral polyhydroxyketone with high diasteroselctivity.
Uses
Tebbe reagent can be used:?????
- For the conversion of carbonyl groups of chlorophyll derivatives into the corresponding exo-methylene (or vinylidene) groups.
- In the synthesis of β-C-glycosides from 3-OH glycol esters.
- As a versatile methylenation reagent for the conversion of ketones and aldehydes to olefins. It offers facile reaction with hindered ketones and allows the conversion of esters to vinyl ethers.
- To olefinate aldehydes.
- To methylenate a chiral polyhydroxyketone with high diasteroselctivity.
Uses
Reagent for the methylenation of carbonyl groups.
General Description
Tebbe reagent is a Lewis acid stabilized organometallic compound, which is used to transform carbonyl groups into β-substituted methylenes. It also reacts with a wide range of carbonyl compounds, including esters, amides, and lactones to yield corresponding olefins.
TEBBE REAGENT Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from TEBBE REAGENT manufacturers
- Product
- TEBBE REAGENT 67719-69-1
- Price
- US $8.00-1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-03