Z-ILE-NH2
- Product Name
- Z-ILE-NH2
- CAS No.
- 86161-49-1
- Chemical Name
- Z-ILE-NH2
- Synonyms
- Z-ILE-NH2;Z-Ile-NH?;Z-L-Ile-NH2;Z-ISOLEUCINE-NH2;L-Z-IsoleucinaMide;Z-L-ISOLEUCINE AMIDE;Cbz-L-Isoleucinamide;Z-L-isoleucine amide99%;Z-(2S,3S)-2-amino-3-methylvaleric acid amide;N-ALPHA-CARBOBENZOXY-L-ISOLEUCINE ALPHA-AMIDE
- CBNumber
- CB2699604
- Molecular Formula
- C14H20N2O3
- Formula Weight
- 264.32
- MOL File
- Mol file
Z-ILE-NH2 Property
- Boiling point:
- 461.5±38.0 °C(Predicted)
- Density
- 1.124±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- pka
- 11.17±0.46(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- I822235
- Product name
- L-Z-Isoleucinamide
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 242796
- Product name
- Z-L-isoleucine amide 99+%
- Packaging
- 1g
- Price
- $200
- Updated
- 2021/12/16
- Product number
- 280774
- Product name
- Z-L-isoleucine amide
- Packaging
- 1g
- Price
- $340
- Updated
- 2021/12/16
- Product number
- 03880
- Product name
- Z-L-isoleucine amide
- Purity
- 99%
- Packaging
- 1G
- Price
- $41.4
- Updated
- 2021/12/16
- Product number
- V8168
- Product name
- L-Z-Isoleucinamide
- Packaging
- 1g
- Price
- $77
- Updated
- 2021/12/16
Z-ILE-NH2 Chemical Properties,Usage,Production
Synthesis
3160-59-6
3282-30-2
86161-49-1
11-1) Preparation of benzyl (2S,3S)-(1-amino-3-methyl-1-oxopentan-2-yl)carbamate 2.63 g (10 mmol) of (2S,3S)-2-(((benzyloxy)carbonyl)amino)-3-methylpentanoic acid was added to a 100 mL solution of dichloromethane pre-cooled to -20°C. 1.40 mL of triethylamine and 1.23 mL of tertiary chloroyl chloride were added sequentially. after 30 min, an ammonia gas bulge was passed into the reaction mixture for 30 min. The resulting precipitate was filtered and the solid was washed with 50 mL of methylene chloride. The combined organic phases were washed sequentially with 2N HCl solution (50 mL x 2) and 50 mL saturated brine. The organic layer was dried with anhydrous MgSO4 and concentrated in vacuum to give 2.49 g (2S,3S)-(1-amino-3-methyl-1-oxopentan-2-yl)carbamic acid benzyl ester (yield: 95%). 1H NMR (CDCl3) δ: 0.9 (m, 6H), 1.2 (m, 1H), 1.5 (m, 1H), 1.8 (m, 1H), 4.0 (m, 1H), 5.1 (s, 2H), 6.5 (d, 1H).
References
[1] Patent: US5587388, 1996, A
[2] Patent: EP601486, 1994, A1
Z-ILE-NH2 Preparation Products And Raw materials
Raw materials
Preparation Products
Z-ILE-NH2 Suppliers
- Tel
- --
- Fax
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- Country
- Japan
- ProdList
- 4811
- Advantage
- 42