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HARRINGTONINE

Product Name
HARRINGTONINE
CAS No.
26833-85-2
Chemical Name
HARRINGTONINE
Synonyms
HT;nsc124147;(3(r))-ter;HARRINGTONIN;HARRINGTONINE;2'R-HARRINGTONINE;HARRINGTONINE98%,99%;Harringtonine 26833-85-2;alkaloidcfromcephalotaxus;HARRINGTONINE(P) USP/EP/BP
CBNumber
CB2702955
Molecular Formula
C28H37NO9
Formula Weight
531.6
MOL File
26833-85-2.mol
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HARRINGTONINE Property

Melting point:
73~75℃
Boiling point:
679.4±55.0 °C(Predicted)
Density 
1.35±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 25 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
form 
A crystalline solid
pka
11.62±0.29(Predicted)
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Safety

RIDADR 
1544
HazardClass 
6.1(a)
PackingGroup 
II
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H310Fatal in contact with skin

H330Fatal if inhaled

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P350IF ON SKIN: Gently wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P310Immediately call a POISON CENTER or doctor/physician.

P320Specific treatment is urgent (see … on this label).

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P363Wash contaminated clothing before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
15361
Product name
Harringtonine
Purity
≥95%
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
15361
Product name
Harringtonine
Purity
≥95%
Packaging
5mg
Price
$109
Updated
2024/03/01
Cayman Chemical
Product number
15361
Product name
Harringtonine
Purity
≥95%
Packaging
10mg
Price
$172
Updated
2024/03/01
TRC
Product number
H105285
Product name
Harringtonin
Packaging
10mg
Price
$150
Updated
2021/12/16
Usbiological
Product number
300401
Product name
Harringtonine
Packaging
20mg
Price
$335
Updated
2021/12/16
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HARRINGTONINE Chemical Properties,Usage,Production

Description

The full structure of harringtonine has now been established from a study of the hydrolysis products of this base.

Description

Harringtonine is a natural alkaloid that inhibits protein synthesis at low micromolar concentrations. It immobilizes ribosomes immediately after the initiation of translation. While harringtonine has drawn some interest in mitigating cancer, its homolog homoharrington is more effective, particularly for chronic myelogenous leukemia. The ability of harringtonine to immobilize initiating ribosomes can be used to capture ribosome-protected mRNA fragments for evaluating translation.

Chemical Properties

White Solid

Uses

A natural product with significant antitumor activities.

Uses

specific anti-leukemia drug

Definition

ChEBI: Harringtonine is an alkaloid.

References

Mikolajczak, Powell, Smith, Tetrahedron, 28, 1995 (1972)
Kelly, McKenna, Christenson, Tetrahedron Lett., 35m (1973)

HARRINGTONINE Preparation Products And Raw materials

Raw materials

Preparation Products

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HARRINGTONINE Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Aktin Chemicals, Inc.
Tel
86-28-85159085
Fax
86-28-85152372
Email
info@aktinchem.com
Country
China
ProdList
297
Advantage
62
Chengdu Climax Biotech Co., Ltd.
Tel
028-83311324 1278112614
Fax
028-83311324
Email
climaxbiotech@gmail.com
Country
China
ProdList
925
Advantage
58
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7553
Advantage
61
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3989
Advantage
66
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2784
Advantage
58
TargetMol Chemicals Inc.
Tel
021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7934
Advantage
58
Chengdu Herbpurify Co.Ltd.
Tel
18302802153 18981717076
Fax
086-28-85377358
Email
2355253622@qq.com
Country
China
ProdList
1104
Advantage
58
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View Lastest Price from HARRINGTONINE manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.
Product
HARRINGTONINE 26833-85-2
Price
US $0.00-0.00/mg
Min. Order
20mg
Purity
98% HPLC
Supply Ability
100kg
Release date
2022-10-21
Shanghai Standard Technology Co., Ltd.
Product
Harringtonine 26833-85-2
Price
US $0.00/mg
Min. Order
5mg
Purity
≥95%(HPLC)
Supply Ability
10 g
Release date
2019-11-26
NanJing Spring & Autumn Biological Engineering CO., LTD.
Product
Harringtonine 26833-85-2 26833-85-2
Price
US $80.00/mg
Min. Order
20mg
Purity
≥98%
Supply Ability
1000.00 kgs
Release date
2019-07-03

26833-85-2, HARRINGTONINERelated Search:


  • (3(r))-ter
  • 4-methyl-cephalotaxin2-hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioate(es
  • alkaloidcfromcephalotaxus
  • cephalotaxine,4-methyl(2r)-2-hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioat
  • nsc124147
  • HARRINGTONIN
  • HARRINGTONINE
  • HT
  • 2'R-HARRINGTONINE
  • Cephalotaxine, 4-methyl (2R)-2-hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioate (ester)
  • HARRINGTONINE98%,99%
  • 2’R-Harringtonine,Harringtonin
  • Harringtonine, 98%, from Taxus chinensis (Pilg.) Rehder
  • 3-[4-Methyl (2R)-2-hydroxy-2-(3-hydroxy-3-Methylbutyl)butanedioate]cephalotaxine
  • 3-methylbutyl)butanedioate (ester), [3(R)]-
  • Cephalotaxine, 4-methyl 2-hydroxy-2-(3-hydroxy-
  • 2-Hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioic acid 1-[(3R)-3-deoxycephalotaxin-3-yl]4-methyl ester
  • Harringtonine 26833-85-2
  • Cephalotaxine, 3-[4-methyl (2R)-2-hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioate]
  • HARRINGTONINE(P) USP/EP/BP
  • 26833-85-2
  • C28H37NO9
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Alkaloids