HARRINGTONINE
- Product Name
- HARRINGTONINE
- CAS No.
- 26833-85-2
- Chemical Name
- HARRINGTONINE
- Synonyms
- HT;nsc124147;(3(r))-ter;HARRINGTONIN;HARRINGTONINE;2'R-HARRINGTONINE;HARRINGTONINE98%,99%;Harringtonine 26833-85-2;alkaloidcfromcephalotaxus;HARRINGTONINE(P) USP/EP/BP
- CBNumber
- CB2702955
- Molecular Formula
- C28H37NO9
- Formula Weight
- 531.6
- MOL File
- 26833-85-2.mol
HARRINGTONINE Property
- Melting point:
- 73～75℃
- Boiling point:
- 679.4±55.0 °C(Predicted)
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 25 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
- form
- A crystalline solid
- pka
- 11.62±0.29(Predicted)
- color
- White to light yellow
Safety
- RIDADR
- 1544
- HazardClass
- 6.1(a)
- PackingGroup
- II
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H300Fatal if swallowed
H310Fatal in contact with skin
H330Fatal if inhaled
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P262Do not get in eyes, on skin, or on clothing.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284Wear respiratory protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P350IF ON SKIN: Gently wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P310Immediately call a POISON CENTER or doctor/physician.
P320Specific treatment is urgent (see … on this label).
P321Specific treatment (see … on this label).
P322Specific measures (see …on this label).
P330Rinse mouth.
P361Remove/Take off immediately all contaminated clothing.
P363Wash contaminated clothing before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 15361
- Product name
- Harringtonine
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
- Product number
- 15361
- Product name
- Harringtonine
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $109
- Updated
- 2024/03/01
- Product number
- 15361
- Product name
- Harringtonine
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $172
- Updated
- 2024/03/01
- Product number
- 300401
- Product name
- Harringtonine
- Packaging
- 20mg
- Price
- $335
- Updated
- 2021/12/16
- Product number
- H105285
- Product name
- Harringtonin
- Packaging
- 10mg
- Price
- $150
- Updated
- 2021/12/16
HARRINGTONINE Chemical Properties,Usage,Production
Description
The full structure of harringtonine has now been established from a study of the hydrolysis products of this base.
Description
Harringtonine is a natural alkaloid that inhibits protein synthesis at low micromolar concentrations. It immobilizes ribosomes immediately after the initiation of translation. While harringtonine has drawn some interest in mitigating cancer, its homolog homoharrington is more effective, particularly for chronic myelogenous leukemia. The ability of harringtonine to immobilize initiating ribosomes can be used to capture ribosome-
Chemical Properties
White Solid
Uses
A natural product with significant antitumor activities.
Uses
specific anti-leukemia drug
Definition
ChEBI: Harringtonine is an alkaloid.
References
Mikolajczak, Powell, Smith, Tetrahedron, 28, 1995 (1972)
Kelly, McKenna, Christenson, Tetrahedron Lett., 35m (1973)
HARRINGTONINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from HARRINGTONINE manufacturers
- Product
- HARRINGTONINE 26833-85-2
- Price
- US $0.00-0.00/mg
- Min. Order
- 20mg
- Purity
- 98% HPLC
- Supply Ability
- 100kg
- Release date
- 2022-10-21
- Product
- Harringtonine 26833-85-2
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥95%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-11-26
- Product
- Harringtonine 26833-85-2 26833-85-2
- Price
- US $80.00/mg
- Min. Order
- 20mg
- Purity
- ≥98%
- Supply Ability
- 1000.00 kgs
- Release date
- 2019-07-03