4-CHLOROBENZO[F]ISOQUINOLINE

Product Name: 4-CHLOROBENZO[F]ISOQUINOLINE
CAS No.: 32081-28-0
Chemical Name: 4-CHLOROBENZO[F]ISOQUINOLINE
Synonyms: CBIQ;CBIQ >=98% (HPLC), solid;4-CHLOROBENZO[F]ISOQUINOLINE;Benz[f]isoquinoline, 4-chloro-
CBNumber: CB2715904
Molecular Formula: C13H8ClN
Formula Weight: 213.66
MOL File: 32081-28-0.mol

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4-CHLOROBENZO[F]ISOQUINOLINE Property

Boiling point:: 400.3±18.0 °C(Predicted)
Density: 1.312±0.06 g/cm3(Predicted)
solubility: DMSO: soluble15mg/mL
pka: 3.21±0.30(Predicted)
form: solid
color: off-white
InChI: 1S/C13H8ClN/c14-13-12-6-5-9-3-1-2-4-10(9)11(12)7-8-15-13/h1-8H
InChIKey: SHQLTRRYZVBEMR-UHFFFAOYSA-N
SMILES: Clc1nccc2c1ccc3ccccc23

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Safety

Hazard Codes: T
Risk Statements: 25-37/38-41
Safety Statements: 26-39-45
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3
Storage Class: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications: Acute Tox. 3 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C6617
Product name: CBIQ
Purity: ≥98% (HPLC), solid
Packaging: 5mg
Price: $180
Updated: 2025/07/31

Sigma-Aldrich

Product number: C6617
Product name: CBIQ
Purity: ≥98% (HPLC), solid
Packaging: 25mg
Price: $711
Updated: 2025/07/31

American Custom Chemicals Corporation

Product number: API0008630
Product name: 4-CHLOROBENZO[F]ISOQUINOLINE
Purity: 95.00%
Packaging: 0.1G
Price: $329
Updated: 2021/12/16

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4-CHLOROBENZO[F]ISOQUINOLINE Chemical Properties,Usage,Production

Biological Activity

CBIQ is an activator of the cystic fibrosis transmembrane conductance regulator (CFTR) and the intermediate-conductance calcium-sensitive K+ channel (KCNN4). CBIQ is a novel tool for a new ion channel; first activator of ΔF508 CFTR, the mutant form of CFTR chloride channel present in 75% of cystic fibrosis patients. Other benzoquinolines act at the normal CFTR but not at ΔF508 CFTR. CBIQ also activates KCNN4, which hyperpolarizes airway epithelial cells to promote anion flux, a further benefit in cystic fibrosis.

4-CHLOROBENZO[F]ISOQUINOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-CHLOROBENZO[F]ISOQUINOLINE Suppliers

China 17 Germany 1 Switzerland 1 United Kingdom 1 United States 3 Global 23

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4720
Advantage: 55

Xi'an Kaixiang Photoelectric Technology Co., Ltd.

Tel: 15332313370 18592059708
Fax: 029-87871708
Email: sales@kxmaterials.com
Country: China
ProdList: 850
Advantage: 55

Accela ChemBio Inc.

Tel: +1-858-6993322
Fax: (+1)-858-876-1948
Email: info@accelachem.com
Country: United States
ProdList: 21193
Advantage: 58

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Email: sales@accelachem.com
Country: China
ProdList: 10467
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 54995
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Ningbo jinuo chemical co., LTD

Tel: 0574-87314919 057487319282
Email: info@nbinno.com
Country: China
ProdList: 7047
Advantage: 58

SINO High Goal Chemical Technology Co., Ltd.

Tel: 021-57646680 18306277365
Email: guoxin@chembiobanksh.com
Country: China
ProdList: 2682
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 59936
Advantage: 58

Suzhou Haiben Pharmaceutical Co., Ltd

Tel: 19353112242
Email: 1816280386@qq.com
Country: China
ProdList: 8045
Advantage: 58

32081-28-0, 4-CHLOROBENZO[F]ISOQUINOLINERelated Search:

1-Chloroisoquinoline 4-CHLOROBENZO[F]ISOQUINOLINE

4-CHLOROBENZO[F]ISOQUINOLINE

CBIQ

Benz[f]isoquinoline, 4-chloro-

CBIQ >=98% (HPLC), solid

32081-28-0

Cell Biology

Cell Signaling and Neuroscience

BioChemical

Chloride Channel Modulators

Ion Channels

Monovalent Ion Channels

Voltage-gated Ion Channels