ChemicalBook > CAS DataBase List > 4-(N-ETHYL-N-4-HYDROXYBUTYL)AMINO-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)PYRROLO[2,3-D]PYRIMIDINE HYDROCHLORIDE

4-(N-ETHYL-N-4-HYDROXYBUTYL)AMINO-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)PYRROLO[2,3-D]PYRIMIDINE HYDROCHLORIDE

Product Name
4-(N-ETHYL-N-4-HYDROXYBUTYL)AMINO-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)PYRROLO[2,3-D]PYRIMIDINE HYDROCHLORIDE
CAS No.
276890-57-4
Chemical Name
4-(N-ETHYL-N-4-HYDROXYBUTYL)AMINO-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)PYRROLO[2,3-D]PYRIMIDINE HYDROCHLORIDE
Synonyms
NIH-3;LWH-63 HYDROCHLORIDE;LWH-63 hydrochloride >=98% (HPLC), solid;1-Butanol, 4-[ethyl[2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-;4-(N-ETHYL-N-4-HYDROXYBUTYL)AMINO-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)PYRROLO[2,3-D]PYRIMIDINE HYDROCHLORIDE;NIH-3, 4-(N-Ethyl-n-4-hydroxybutyl)amino-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidine hydrochloride
CBNumber
CB2717968
Molecular Formula
C24H34N4O
Formula Weight
394.55
MOL File
276890-57-4.mol
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4-(N-ETHYL-N-4-HYDROXYBUTYL)AMINO-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)PYRROLO[2,3-D]PYRIMIDINE HYDROCHLORIDE Property

storage temp. 
2-8°C
solubility 
DMSO: ~10 mg/mL
form 
solid
color 
light brown
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L9167
Product name
LWH-63 hydrochloride
Purity
≥98% (HPLC), solid
Packaging
50mg
Price
$939
Updated
2024/03/01
Sigma-Aldrich
Product number
L9167
Product name
LWH-63 hydrochloride
Purity
≥98% (HPLC), solid
Packaging
10mg
Price
$240
Updated
2023/06/20
American Custom Chemicals Corporation
Product number
INB0001068
Product name
LWH-63 HYDROCHLORIDE
Purity
95.00%
Packaging
10MG
Price
$712.49
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0001068
Product name
LWH-63 HYDROCHLORIDE
Purity
95.00%
Packaging
50MG
Price
$1192.14
Updated
2021/12/16
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4-(N-ETHYL-N-4-HYDROXYBUTYL)AMINO-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)PYRROLO[2,3-D]PYRIMIDINE HYDROCHLORIDE Chemical Properties,Usage,Production

Biological Activity

Non-peptide CRF1 corticotrophin-releasing factor antagonist. Ki = 0.68 nM; blocks ethanol-induced effects as well as CRF effects in mice, suggesting a possible therapeutic target for the treatment of stress-induced alcohol drinking.

4-(N-ETHYL-N-4-HYDROXYBUTYL)AMINO-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)PYRROLO[2,3-D]PYRIMIDINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(N-ETHYL-N-4-HYDROXYBUTYL)AMINO-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)PYRROLO[2,3-D]PYRIMIDINE HYDROCHLORIDE Suppliers

China 1 Switzerland 1 United States 1 Global 3
Riedel-de Haen AG
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Fax
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Country
United States
ProdList
6773
Advantage
87

276890-57-4, 4-(N-ETHYL-N-4-HYDROXYBUTYL)AMINO-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)PYRROLO[2,3-D]PYRIMIDINE HYDROCHLORIDERelated Search:


  • NIH-3
  • NIH-3, 4-(N-Ethyl-n-4-hydroxybutyl)amino-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidine hydrochloride
  • LWH-63 HYDROCHLORIDE
  • 4-(N-ETHYL-N-4-HYDROXYBUTYL)AMINO-2,5,6-TRIMETHYL-7-(2,4,6-TRIMETHYLPHENYL)PYRROLO[2,3-D]PYRIMIDINE HYDROCHLORIDE
  • 1-Butanol, 4-[ethyl[2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-
  • LWH-63 hydrochloride >=98% (HPLC), solid
  • 276890-57-4
  • C24H35ClN4O
  • C24H34N4O