ChemicalBook > CAS DataBase List > PYR-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2

PYR-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2

Product Name
PYR-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2
CAS No.
143675-79-0
Chemical Name
PYR-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2
Synonyms
GP ANTAGONIST-2;G PROTEIN ANTAGONIST;PROTEIN G ANTAGONIST 2;G-PROTEIN ANTAGONIST-2;G-PROTEIN ANTAGONIST PEPTIDE;G Protein Antagonist >=90% (HPLC);PYR-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2;Glp-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH2;pglu-gln-d-trp-phe-d-trp-d-trp-met-nh2;(pglu5,D-trp7,9,10)-substance*P fragment
CBNumber
CB2721202
Molecular Formula
C57H64N12O9S
Formula Weight
1093.26
MOL File
143675-79-0.mol
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PYR-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2 Property

Boiling point:
1638.4±65.0 °C(Predicted)
Density 
1.374±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Soluble to 2 mg/ml in DMSO
pka
13.12±0.20(Predicted)
Sequence
{Glp}-Gln-Trp-Phe-Trp-Trp-Met-NH2
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S8031
Product name
[pGlu5, D-Trp7,9,10]-Substance P Fragment 5-11
Purity
≥90% (HPLC)
Packaging
1mg
Price
$303
Updated
2023/06/20
Tocris
Product number
1931
Product name
G-ProteinAntagonistpeptide
Packaging
1
Price
$214
Updated
2021/12/16
Usbiological
Product number
G8598-02
Product name
G-Protein Antagonist
Packaging
1mg
Price
$531
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0001497
Product name
PYR-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2
Purity
95.00%
Packaging
1MG
Price
$709.46
Updated
2021/12/16
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PYR-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2 Chemical Properties,Usage,Production

Uses

G-Protein antagonist peptide is the substance P-related peptide that inhibits binding of G proteins to their receptors. G-Protein antagonist peptide competitively and reversibly inhibits M2 muscarinic receptor activation of Gi or Go and inhibits Gs activation by β-adrenoceptors.

References

[1] Mukai H, et al. G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding. J Biol Chem. 1992;267(23):16237-16243. PMID:1379592

PYR-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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PYR-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2 Suppliers

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143675-79-0, PYR-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2Related Search:


  • G PROTEIN ANTAGONIST
  • G-PROTEIN ANTAGONIST-2
  • G-PROTEIN ANTAGONIST PEPTIDE
  • GP ANTAGONIST-2
  • SUBSTANCE P [PGLU5,D-TRP7,9,10]-FRAGMENT 5-11
  • PROTEIN G ANTAGONIST 2
  • PYR-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2
  • (pglu5,D-trp7,9,10)-substance*P fragment
  • [pglu5, d-trp7,9,10]-substance p fragment 5-11
  • pglu-gln-d-trp-phe-d-trp-d-trp-met-nh2
  • Substance P, fragment 5-11, [pGlu5, D-Trp7,9,10]
  • L-Methioninamide, 5-oxo-L-prolyl-L-glutaminyl-D-tryptophyl-L-phenylalanyl-D-tryptophyl-D-tryptophyl-
  • G Protein Antagonist >=90% (HPLC)
  • Glp-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH2
  • G Protein Antagonist Pyr-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH2
  • 143675-79-0
  • C57H64N12O9S
  • Tachykinins
  • Reagents
  • Peptides
  • G Protein Function
  • G Proteins and Cyclic Nucleotides
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Biochemicals and Reagents
  • Antagonist
  • Amino Acids and Peptides
  • BioChemical