ChemicalBook > CAS DataBase List > Z-GLY-GLY-PHE-CHLOROMETHYLKETONE

Z-GLY-GLY-PHE-CHLOROMETHYLKETONE

Product Name
Z-GLY-GLY-PHE-CHLOROMETHYLKETONE
CAS No.
35172-59-9
Chemical Name
Z-GLY-GLY-PHE-CHLOROMETHYLKETONE
Synonyms
Z-GGF-CMK;Z-GLY-GLY-PHE-CMK;Z-GLY-GLY-PHE-CHLOROMETHYLKETONE;N-cbz-gly-gly-phe chloromethyl ketone;N-carbobenzyloxy-Gly-Gly-Phe chloromethyl ketone;Glycinamide, N-[(phenylmethoxy)carbonyl]glycyl-N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-;benzyl N-[2-[[2-[[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]carbamate
CBNumber
CB2729268
Molecular Formula
C22H24ClN3O5
Formula Weight
445.9
MOL File
35172-59-9.mol
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Z-GLY-GLY-PHE-CHLOROMETHYLKETONE Property

Boiling point:
751.7±60.0 °C(Predicted)
Density 
1.281±0.06 g/cm3(Predicted)
storage temp. 
-15°C
pka
11.03±0.46(Predicted)
Sequence
{Cbz}-Gly-Gly-Phe-{CMK}
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
PEP0009027
Product name
Z-GLY-GLY-PHE-CHLOROMETHYLKETONE
Purity
98.00%
Packaging
50MG
Price
$1495.73
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0009027
Product name
Z-GLY-GLY-PHE-CHLOROMETHYLKETONE
Purity
98.00%
Packaging
0.1G
Price
$1903
Updated
2021/12/16
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Z-GLY-GLY-PHE-CHLOROMETHYLKETONE Chemical Properties,Usage,Production

Uses

Z-GGF-CMK is a protease inhibitor, inhibits ClpP1P2 and proteasome. Z-GGF-CMK exhibits cytotoxic activity against HepG2 cells with a CC50 value of 125 μM[1].

References

[1] Moreira W, et, al. Bortezomib Warhead-Switch Confers Dual Activity against Mycobacterial Caseinolytic Protease and Proteasome and Selectivity against Human Proteasome. Front Microbiol. 2017 Apr 27;8:746. DOI:10.3389/fmicb.2017.00746

Z-GLY-GLY-PHE-CHLOROMETHYLKETONE Preparation Products And Raw materials

Raw materials

Preparation Products

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Z-GLY-GLY-PHE-CHLOROMETHYLKETONE Suppliers

GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
7408
Advantage
58
Nanchang Tianzhen Biotechnology Co., Ltd
Tel
13758194781 13173652190
Email
522013271@qq.com
Country
China
ProdList
2395
Advantage
58
Nanjing TGpeptide Biotechnology Co.,Ltd.
Tel
18115476705
Email
sales@tgpeptide.com
Country
China
ProdList
3058
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
29668
Advantage
58
Nanjing Yuanpeptide Biotech Co.,Ltd.
Tel
18168071971
Email
support@yuan-peptide.com
Country
China
ProdList
2983
Advantage
58
Shaoxing Junyu Biotechnology Co., LTD
Tel
0571-0571-88211921 19105816207
Email
sales4@gotopbio.com
Country
China
ProdList
5144
Advantage
58

35172-59-9, Z-GLY-GLY-PHE-CHLOROMETHYLKETONERelated Search:


  • N-carbobenzyloxy-Gly-Gly-Phe chloromethyl ketone
  • Z-GLY-GLY-PHE-CHLOROMETHYLKETONE
  • Z-GLY-GLY-PHE-CMK
  • N-cbz-gly-gly-phe chloromethyl ketone
  • benzyl N-[2-[[2-[[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]carbamate
  • Glycinamide, N-[(phenylmethoxy)carbonyl]glycyl-N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-
  • Z-GGF-CMK
  • 35172-59-9
  • C22H24ClN3O5
  • C22H24N3O5Cl