ChemicalBook > CAS DataBase List > 1-BOC-1,12-DIAMINODODECANE

1-BOC-1,12-DIAMINODODECANE

Product Name
1-BOC-1,12-DIAMINODODECANE
CAS No.
109792-60-1
Chemical Name
1-BOC-1,12-DIAMINODODECANE
Synonyms
Boc-DADdec;Boc-NH-C12-NH2;1-BOC-1,12-DIAMINODO;N-Boc-1,12-dodecanediamine;1-BOC-1,12-DIAMINODODECANE;N-Boc-1,12-diaminododecane;N-Boc-dodecane-1,12-diamine;N1-Boc-1,12-dodecanediamine;tert-butyl 2,13-diaMinotridecanoate;TERT-BUTYL 12-AMINODODECYLCARBAMATE
CBNumber
CB2734044
Molecular Formula
C17H36N2O2
Formula Weight
300.48
MOL File
109792-60-1.mol
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1-BOC-1,12-DIAMINODODECANE Property

Melting point:
84-86 °C
Boiling point:
409.2±18.0 °C(Predicted)
Density 
0.924±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
form 
solid
pka
12.94±0.46(Predicted)
color 
Pale yellow
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Safety

Hazard Codes 
Xi
Hazard Note 
Irritant
HS Code 
2924190090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC
Product number
B808000
Product name
12-(tert-Butoxycarbonylamino)dodecylamine
Packaging
100mg
Price
$120
Updated
2021/12/16
TRC
Product number
B808000
Product name
12-(tert-Butoxycarbonylamino)dodecylamine
Packaging
5g
Price
$825
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0017041
Product name
1,12-DIAMINODODECANE, N-BOC PROTECTED
Purity
95.00%
Packaging
1G
Price
$810.35
Updated
2021/12/16
SynQuest Laboratories
Product number
4156-1-Y3
Product name
Dodecane-1,12-diamine, N-Boc protected
Purity
97%
Packaging
50mg
Price
$141
Updated
2021/12/16
SynQuest Laboratories
Product number
4156-1-Y3
Product name
Dodecane-1,12-diamine, N-Boc protected
Purity
97%
Packaging
250mg
Price
$464
Updated
2021/12/16
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1-BOC-1,12-DIAMINODODECANE Chemical Properties,Usage,Production

Description

tert-Butyl (12-aminododecyl)carbamate can be used as a PROTAC linker in the synthesis of PROTACs. tert-Butyl (12-aminododecyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Uses

12-(tert-Butoxycarbonylamino)dodecylamine can be used to synthesize inhibitors of topoisomerase I for use as anticancer agents.

1-BOC-1,12-DIAMINODODECANE Preparation Products And Raw materials

Raw materials

Preparation Products

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109792-60-1, 1-BOC-1,12-DIAMINODODECANERelated Search:


  • 1-BOC-1,12-DIAMINODODECANE
  • Boc-DADdec
  • N-t-Butyloxycarbonyl-1,12-diaminododecane
  • tert-butyl 2,13-diaMinotridecanoate
  • 1,12-Diaminododecane, N-BOC protected, tert-Butyl (12-aminododec-1-yl)carbamate
  • Dodecane-1,12-diamine, N-BOC protected 97%
  • 12-(tert-ButoxycarbonylaMino)dodecylaMine
  • N-Boc-1,12-dodecanediamine
  • tert-Butyl N-(12-aminododecyl)carbamate
  • N-Boc-1,12-diaminododecane
  • N-Boc-dodecane-1,12-diamine
  • 1-BOC-1,12-DIAMINODO
  • 1,12-DIAMINODODECANE, N-BOC PROTECTED
  • TERT-BUTYL 12-AMINODODECYLCARBAMATE
  • 1,12-Diaminododecane, N-BOC protected 97%
  • Dodecane-1,12-diamine, N-BOC protected
  • Boc-NH-C12-NH2
  • Carbamic acid, N-(12-aminododecyl)-, 1,1-dimethylethyl ester
  • PROTAC Linkers,Boc-NH-C-12-NH2,Inhibitor,inhibit,Boc NH C12 NH2,BocNHC12NH2
  • N1-Boc-1,12-dodecanediamine
  • ert-Butyl (12-aminododecyl)carbamate , Boc-NH-C12-NH2
  • 109792-60-1
  • C17H36N2O2
  • pharmacetical