5-Ethyluracil
Application- Product Name
- 5-Ethyluracil
- CAS No.
- 4212-49-1
- Chemical Name
- 5-Ethyluracil
- Synonyms
- 5-ethylpyriMidine-2,4(1H,3H)-dione;HOMOTHYMINE;5-ETHYLURACIL;AURORA KA-580;5-ethvluracil;5-Ethyluracil>5-Ethyluracil, 98+%;5-Ethyluracil USP/EP/BP;DIHYDROXY-5-ETHYLPYRIMIDINE;5-Ethyl-1H-pyrimidine-2,4-dione
- CBNumber
- CB2736785
- Molecular Formula
- C6H8N2O2
- Formula Weight
- 140.14
- MOL File
- 4212-49-1.mol
5-Ethyluracil Property
- Melting point:
- >300 °C(lit.)
- Density
- 1.164±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- 9.21±0.10(Predicted)
- color
- White to Light yellow
- λmax
- 265nm(EtOH)(lit.)
- BRN
- 119494
- InChI
- InChI=1S/C6H8N2O2/c1-2-4-3-7-6(10)8-5(4)9/h3H,2H2,1H3,(H2,7,8,9,10)
- InChIKey
- RHIULBJJKFDJPR-UHFFFAOYSA-N
- SMILES
- C1(=O)NC=C(CC)C(=O)N1
- CAS DataBase Reference
- 4212-49-1(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- E0807
- Product name
- 5-Ethyluracil
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $23
- Updated
- 2025/07/31
- Product number
- E0807
- Product name
- 5-Ethyluracil
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $63
- Updated
- 2025/07/31
- Product number
- E818270
- Product name
- 5-Ethyluracil
- Packaging
- 500mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- L819
- Product name
- 5-Ethyluracil
- Packaging
- 1kg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- NUC0000636
- Product name
- 5-ETHYLURACIL
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $400.25
- Updated
- 2021/12/16
5-Ethyluracil Chemical Properties,Usage,Production
Application
5-Ethyluracil is a pharmaceutical intermediate and an organic synthesis intermediate that can be used in laboratory research and development processes as well as in chemical and pharmaceutical synthesis.
Chemical Properties
Solid
Synthesis
36873-42-4
57-13-6
4212-49-1
Urea (19.39 g, 0.32 mol, JT Baker) was slowly added to fuming sulfuric acid (26-29.5% free SO3, 135 mL, 2.65 mol, Aldrich) under cooling in an ice-water bath over a period of 20 min, and the reaction temperature was controlled to be maintained at 8 to 15°C. After stirring for 30 min, ethyl 2-formylbutyrate was added dropwise over 18 min ( 46.55 g, 0.32 mol, from Example LC), keeping the reaction temperature constant. After continued stirring for 30 minutes, a second portion of urea (15.07 g, 0.25 mol) was added over 10 minutes at the same temperature. Subsequently, the reaction mixture was stirred at room temperature for 65 hours and then heated at 90-100°C for 2 hours (gas was observed to escape, the reaction was exothermic, and the temperature rose to 110°C). Upon completion of the reaction, the mixture was cooled to 30 °C using an ice water bath and ice (270 g) was slowly added to ensure that the temperature did not exceed 35 °C. The mixture was further cooled to 5 °C and stirred for 20 min. The precipitated solid was collected by filtration, washed sequentially with cold water, hexane and ether and dried by filtration to give 5-ethyluracil in 38.85 g (85.9%) yield.
References
[1] Patent: WO2004/41821, 2004, A1. Location in patent: Page 26
5-Ethyluracil Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Ethyluracil manufacturers
- Product
- 5-Ethyluracil 4212-49-1
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%min
- Supply Ability
- 20tons
- Release date
- 2025-08-27
- Product
- 5-Ethyluracil 4212-49-1
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2025-03-14
- Product
- 5-ethyluracil 4212-49-1
- Price
- US $25.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100tons
- Release date
- 2023-11-09