ChemicalBook > CAS DataBase List > 15(R)-15-METHYL PROSTAGLANDIN A2

15(R)-15-METHYL PROSTAGLANDIN A2

Product Name
15(R)-15-METHYL PROSTAGLANDIN A2
CAS No.
96440-68-5
Chemical Name
15(R)-15-METHYL PROSTAGLANDIN A2
Synonyms
Reaxys ID: 3005095;UEBXYYKXJUBAJX-ULDSDQABSA-N;15(R)-15-METHYL PROSTAGLANDIN A2;9-OXO-15R-HYDROXY-15-METHYL-PROSTA-5Z,10,13E-TRIEN-1-OIC ACID;9-Oxo-15R-hydroxy-15-hethyl-prosta-5Z,10,13E-trien-1-oic acid;Prosta-5,10,13-trien-1-oic acid, 15-hydroxy-15-methyl-9-oxo-, (5Z,13E,15R)-
CBNumber
CB2740867
Molecular Formula
C21H32O4
Formula Weight
348.48
MOL File
96440-68-5.mol
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15(R)-15-METHYL PROSTAGLANDIN A2 Property

Boiling point:
520.9±50.0 °C(Predicted)
Density 
1.091±0.06 g/cm3(Predicted)
solubility 
DMF: >75 mg/ml (from PGA1); DMSO: >50 mg/ml (from PGA1); Ethanol: >100 mg/ml (from PGA1); PBS pH 7.2: >2.4 mg/ml (from PGA1)
pka
4.75±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H302Harmful if swallowed

H319Causes serious eye irritation

H336May cause drowsiness or dizziness

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10270
Product name
15(R)-15-methyl Prostaglandin A2
Purity
≥98%
Packaging
1mg
Price
$55
Updated
2024/03/01
Cayman Chemical
Product number
10270
Product name
15(R)-15-methyl Prostaglandin A2
Purity
≥98%
Packaging
5mg
Price
$236
Updated
2024/03/01
Cayman Chemical
Product number
10270
Product name
15(R)-15-methyl Prostaglandin A2
Purity
≥98%
Packaging
10mg
Price
$420
Updated
2024/03/01
AK Scientific
Product number
1205AH
Product name
15(R)-15-MethylprostaglandinA2
Packaging
1mg
Price
$158
Updated
2021/12/16
AHH
Product number
MT-20543
Product name
9-Oxo-15R-hydroxy-15-hethyl-prosta-5Z,10,13E-trien-1-oicacid
Purity
98%
Packaging
0.01g
Price
$300
Updated
2021/12/16
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15(R)-15-METHYL PROSTAGLANDIN A2 Chemical Properties,Usage,Production

Description

Arbaprostil (15(R)-15-methyl prostaglandin E2) is a synthetic prostaglandin E2 (PGE2) analog developed for its cytoprotective activity.1 15(R)-15-methyl Prostaglandin A2 (15(R)-15-methyl PGA2) is one of several impurities which are possible in the production of commercial lots of bulk arbaprostil.2 The pharmacology and EP receptor binding affinity for 15(R)-15-methyl PGA2 has not been published.

Definition

ChEBI: 15(R)-15-methyl Prostaglandin A2 is a prostanoid.

References

1. Collins, P.W. Misoprostol: Discovery, development, and clinical applications Med. Res. Rev. 10(2),149-172(1990).
2. Kissinger, L.D., and Robins, R.H. Silver-modified mobile phase for normal-phase liquid chromatographic determination of prostaglandins and their 5,6-trans isomers in prostaglandin bulk drugs and triacetin solutions J. Chromatogr. 321(2),353-362(1985).

15(R)-15-METHYL PROSTAGLANDIN A2 Preparation Products And Raw materials

Raw materials

Preparation Products

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15(R)-15-METHYL PROSTAGLANDIN A2 Suppliers

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96440-68-5, 15(R)-15-METHYL PROSTAGLANDIN A2Related Search:


  • 15(R)-15-METHYL PROSTAGLANDIN A2
  • 9-Oxo-15R-hydroxy-15-hethyl-prosta-5Z,10,13E-trien-1-oic acid
  • UEBXYYKXJUBAJX-ULDSDQABSA-N
  • 9-OXO-15R-HYDROXY-15-METHYL-PROSTA-5Z,10,13E-TRIEN-1-OIC ACID
  • Reaxys ID: 3005095
  • Prosta-5,10,13-trien-1-oic acid, 15-hydroxy-15-methyl-9-oxo-, (5Z,13E,15R)-
  • 96440-68-5