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Nalpha-Cbz-L-Arginine

Product Name
Nalpha-Cbz-L-Arginine
CAS No.
1234-35-1
Chemical Name
Nalpha-Cbz-L-Arginine
Synonyms
Z-ARG;z-aga-oh;Z-ARG-OH;CBZ-L-Arg;CBZ-ARG-OH;Z-ARGININE;Z-L-ARG-OH;CBZ-L-ARG-OH;Z-L-ARGININE;CBZ-L-ARGNINE
CBNumber
CB2768142
Molecular Formula
C14H20N4O4
Formula Weight
308.33
MOL File
1234-35-1.mol
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Nalpha-Cbz-L-Arginine Property

Melting point:
171-174 °C (dec.)(lit.)
alpha 
-11 º (c=0.5, 0.5N HCl 24 ºC)
Boiling point:
448.73°C (rough estimate)
Density 
1.1765 (rough estimate)
refractive index 
-10 ° (C=5.5, 0.2mol/L HCl)
storage temp. 
2-8°C
solubility 
DMSO, Water
form 
Solid
pka
3.90±0.21(Predicted)
color 
White
optical activity
[α]20/D 9±1°, c = 5% in 1 M HCl
BRN 
2169267
CAS DataBase Reference
1234-35-1(CAS DataBase Reference)
EPA Substance Registry System
L-Arginine, N2-[(phenylmethoxy)carbonyl]- (1234-35-1)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
24/25-36-26-S24/25
WGK Germany 
3
TSCA 
Yes
HS Code 
29252900
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
95930
Product name
Z-Arg-OH
Purity
≥96.0% (NT)
Packaging
5g
Price
$42.5
Updated
2022/05/15
TCI Chemical
Product number
C0757
Product name
Nalpha-Carbobenzoxy-L-arginine
Purity
>97.0%(T)
Packaging
1g
Price
$35
Updated
2025/07/31
TCI Chemical
Product number
C0757
Product name
Nalpha-Carbobenzoxy-L-arginine
Purity
>97.0%(T)
Packaging
25g
Price
$93
Updated
2025/07/31
TRC
Product number
A769400
Product name
Z-L-Arginine
Packaging
10g
Price
$55
Updated
2021/12/16
TRC
Product number
A769400
Product name
Z-L-Arginine
Packaging
100g
Price
$225
Updated
2021/12/16
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Nalpha-Cbz-L-Arginine Chemical Properties,Usage,Production

Chemical Properties

white powder

Uses

Z-L-Arginine is used in the synthesis of renin inhibitors containing phosphorous acid derivatives at the scissile bond. Also used in the synthesis of a peptide deformylase inhibitor BB-3497.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

420-04-2

2640-58-6

1234-35-1

The general procedure for the synthesis of Cbz-arginine from cyanamide and (S)-5-amino-2-(benzyloxycarbonyloxyamino)pentanoic acid was as follows: to a solution of water (2.5 mL) containing p-methoxyaniline (1b, 61.6 mg, 0.50 μmol) and cyanamide (25.2 mg, 0.60 μmol) was added scandium trifluoromethanesulfonate (Sc(OTf)3, at room temperature. 24.6 mg, 50 nmol). The reaction mixture was stirred at 100 °C for 2 days. After completion of the reaction, the reaction mixture was washed with chloroform (3 x 10 mL) extraction. The aqueous layer was separated and concentrated under vacuum. The residue was purified by filtration through a silica gel pad (eluent: chloroform-methanol, 20:1, v/v).

References

[1] Synlett, 2014, vol. 25, # 9, p. 1302 - 1306

Nalpha-Cbz-L-Arginine Preparation Products And Raw materials

Raw materials

Preparation Products

N-Phospho-L-arginine PHOSPHO-L-ARGININE SODIUM
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Nalpha-Cbz-L-Arginine Suppliers

Americas 1 China 202 Europe 2 France 3 Germany 8 India 22 Japan 5 South Korea 1 Switzerland 5 United Kingdom 13 United States 53 Global 315
Matrix Fine Chemicals GmbH
Tel
--
Fax
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Email
nfo@matrix-fine-chemicals.com
Country
Switzerland
ProdList
6968
Advantage
58
Christof Senn Laboratories AG
Tel
--
Fax
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Email
christof.senn@cslabs.ch
Country
Switzerland
ProdList
502
Advantage
58
Bachem AG
Tel
--
Fax
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Email
sales.ch@bachem.com
Country
Switzerland
ProdList
438
Advantage
58
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
Senn Chemicals AG
Tel
--
Fax
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Email
swiss@sennchem.com
Country
Switzerland
ProdList
3143
Advantage
71
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View Lastest Price from Nalpha-Cbz-L-Arginine manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Cbz-Arg-OH 1234-35-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2023-12-29
Shaanxi Dideu Medichem Co. Ltd
Product
Nalpha-Cbz-L-Arginine 1234-35-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
10000KG
Release date
2024-08-08
Career Henan Chemical Co
Product
Nalpha-Cbz-L-Arginine 1234-35-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20kg
Release date
2018-08-15

1234-35-1, Nalpha-Cbz-L-ArginineRelated Search:

Cbz-L-arginine hydrochloride Benzyloxyacetyl chloride L(+)-Arginine ARGINASE Trimethoprim Z-ARG-OH HCL Arginine Z-ARG(MTR)-OH CHA Z-ARG(NO2)-OH Z-ARG(Z)2-OH BOC-ARG(Z)-OH BPOC-ARG(MTR)-OH Z-ARG(MTR)-OTBU N-ALPHA-BENZYLOXYCARBONYL-N'-2,2,4,6,7-PENTAMETHYLDIHYDROBENZOFURAN-5-SULFONYL-L-ARGININE CYCLOHEXYLAMINE Z-ARG(PMC)-OME 2-ARG-OBZL(4-NO2)HYDROCHLORIDE AND HYDROBROMIDE Z-ARG(MBS)-OH DCHA Z-ARG(TOS)-OH CHA

  • n2-[(phenylmethoxy)carbonyl]-l-arginin
  • BenzyloxycarbonylLarginine
  • N(alpha)-Benzyloxycarbonyl-L-arginine~Z-Arg-OH
  • Na-Benzyloxycarbonyl-L-arginine
  • na-cbz-L-arginine free acid
  • N2-[(phenylmethoxy)carbonyl]-L-arginine
  • N<sub>α</sub>-Z-L-Arginine
  • N<sup>2</sup>-Carbobenzyloxy-L-arginine
  • N-α-Z-L-arginine
  • N-Carbobenzyloxy-L-arginine
  • Nɑ-Benzyloxycarbonyl-L-arginine, 99%
  • Nalpha-Cbz-L-Arginin
  • CBZ-L-ARGNINE
  • n(à)-cbz-l-arginine
  • nà-benzyloxycarbonyl-l-arginine
  • z-aga-oh
  • Z-ARG
  • N-BENZYLOXYCARBONYL-L-ARGININE(Z-ARG-OH)
  • CBZ-L-Arg
  • CBZ-L-Arginine (Z-Arg-OH)
  • Nalpha-Cbz-L-arginine Z-Arg-OH
  • (S)-2-(((benzyloxy)carbonyl)aMino)-5-guanidinopentanoic acid
  • Nalpha-Carbobenzyl
  • Z-L-arginine≥ 99% (HPLC)
  • (2S)-5-(diaminomethylideneammonio)-2-(phenylmethoxycarbonylamino)pentanoate
  • (2S)-2-{[(benzyloxy)carbonyl]amino}-5-carbamimidamidopentanoic acid
  • Nalpha-Carbobenzyloxy-L-arginine, 98.5%
  • Z-L-ARGININE extrapure
  • N(sup 2)-carbobenzyloxy-L-arginine
  • Nα-Z-L-Arginine, N2-Carbobenzyloxy-L-arginine
  • CBZ-ARG-OH
  • CBZ-L-ARGININE
  • CBZ-L-ARG-OH
  • N-BENZYLOXYCARBONYL-L-ARGININE
  • N-ALPHA-BENZYLOXYCARBONYL-L-ARGININE
  • Z-ARG-OH
  • Z-ARGININE
  • Z-L-ARGININE
  • Z-L-ARG-OH
  • L-ARGININE, N2-[(PHENYLMETHOXY)CARBONYL]-
  • Nα-Carbobenzoxy-L-arginine ,98%
  • N-CBZ-L-ARGININE-OH
  • N2-CARBOBENZYLOXY-L-ARGININE
  • NALPHA-CBZ-L-ARGININE
  • N-ALPHA-CARBOBENZYLOXY-L-ARGININE
  • NALPHA-CARBOBENZOXY-L-ARGININE
  • N-ALPHA-Z-L-ARGININE
  • N-CARBOBENZOXY-L-ARGININE
  • (2S)-5-(Diaminomethylideneamino)-2-(phenylmethoxycarbonylamino)pentanoic acid
  • (S)-2-(Benzyloxycarbonylamino)-5-(amidinoamino)valeric acid
  • Nα-(Benzyloxycarbonyl)arginine
  • Nα-Cbz-L-Arg-OH
  • Nalpha-Carbobenzyloxy-L-arginine,98%
  • Nα-Carbobenzoxy-L-arginine &gt
  • Nalpha-Cbz-L-Arginine USP/EP/BP
  • Nα-Carbobenzoxy-L-arginine
  • Nα -Cbz-L-arginine, 99% [Z-Arg-OH]
  • 1234-35-1