DADEPYLIPQQG

Product Name
DADEPYLIPQQG
Chemical Name
DADEPYLIPQQG
Synonyms
EGFR;DADEPYLIPQQG;EGFR (988-998);DADEY(PO3)LIPQQG;Mouse Anti-EGFR antibody;Rat EGFR Protein, His Tag;Mouse EGFR Protein, Fc Tag;Human EGFR Protein, Fc Tag;Mouse EGFR Protein, His Tag;Human EGFR Protein, His Tag
CBNumber
CB2770154
Molecular Formula
C54H82N13O24P
Formula Weight
1328.28
MOL File
Mol file
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DADEPYLIPQQG Property

storage temp. 
-20°C
form 
lyophilized powder
color 
white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E3641
Product name
Epidermal Growth Factor Receptor human
Purity
buffered aqueous glycerol solution, 5,000-30,000?units/mg protein (Lowry)
Packaging
500units
Price
$759
Updated
2024/03/01
Sigma-Aldrich
Product number
E2645
Product name
Epidermal Growth Factor Receptor human
Purity
lyophilized powder, ≥15,000?units/mg protein (Bradford)
Packaging
500UNITS
Price
$586
Updated
2023/06/20
Usbiological
Product number
369876
Product name
EGFR
Packaging
48Tests
Price
$588
Updated
2021/12/16
Usbiological
Product number
382729
Product name
EGFR
Packaging
96Tests
Price
$669
Updated
2021/12/16
Usbiological
Product number
472035
Product name
EGFR
Packaging
96Tests
Price
$731
Updated
2021/12/16
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DADEPYLIPQQG Chemical Properties,Usage,Production

General Description

Epidermal growth factor receptor (EGFR) belongs to a family of cell surface receptors called receptor tyrosine kinases (RTKs), and is also the most studied member of this family. It is made up of an ectodomain (ECD), which contains four subdomains called DI-DIV, a transmembrane region, and a cytoplasmic tyrosine kinase domain (TKD). Binding of the ligand induces conformational changes in the ECD, which leads to the dimerization of EGFR. This results in the activation of the TKD, and the subsequent signal transduction. This receptor has a molecular weight of ～178kDa.

Biochem/physiol Actions

EGF exerts its actions by binding to the EGF receptor (EGFR), a 170 kDa glycoprotein having EGF-activated protein tyrosine kinase activity. Even in the absence of EGF-like ligands, EGFR can participate in cellular responses elicited by several other stimuli. High levels of EGFR are expressed in approximately one third of human epithelial tumors, and in the cancers of the bladder, breast or lung that have poor clinical prognosis, hence the interest in targeting EGFR.

DADEPYLIPQQG Preparation Products And Raw materials

Raw materials

Preparation Products

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DADEPYLIPQQG Suppliers

China 35 United Kingdom 2 United States 4 Global 41
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
VWR International
Tel
--
Fax
--
Email
solutions@vwr.com
Country
United Kingdom
ProdList
6548
Advantage
82

DADEPYLIPQQGRelated Search:


  • EGFR
  • DADEPYLIPQQG
  • DADEY(PO3)LIPQQG
  • EGF RECEPTOR SUBSTRATE 2 [DADE-PY-LIPQQG]
  • EGFR (988-998)
  • H-ASP-ALA-ASP-GLU-PTYR-LEU-ILE-PRO-GLN-GLN-GLY-OH
  • PROTEIN TYROSINE PHOSPHATASE 1B SUBSTRATE I
  • PROTEIN TYROSINE PHOSPHATASE 1B SUBSTRATE
  • Epidermal Growth Factor Receptor human
  • Recombinant Human EGFR Protein, Fc Tag
  • Human EGFR Protein, His & GST Tag
  • Mouse EGFR Protein, Fc Tag
  • Canine EGFR Protein, His Tag
  • Rat EGFR Protein, His Tag
  • Cynomolgus Monkey EGFR Protein, His Tag
  • Human EGFR Protein, Fc Tag
  • Human EGFR Protein, C13 & N15 Tag
  • Human EGFR Protein, Strep Tag
  • Human EGFR Protein, Avi & His Tag
  • Rhesus Monkey EGFR Protein, Fc Tag
  • Recombinant Human EGFR Protein, His tag
  • Rhesus Monkey EGFR Protein, His Tag
  • Mouse EGFR Protein, His Tag
  • Human EGFR Protein, His Tag
  • Mouse Anti-EGFR antibody
  • protein kinase
  • peptide