1-METHOXY-9ALPHA, 11ALPHA, 15S-TRIHYDROXYPROSTA-5Z, 13E-DIENE
- Product Name
- 1-METHOXY-9ALPHA, 11ALPHA, 15S-TRIHYDROXYPROSTA-5Z, 13E-DIENE
- CAS No.
- 143656-18-2
- Chemical Name
- 1-METHOXY-9ALPHA, 11ALPHA, 15S-TRIHYDROXYPROSTA-5Z, 13E-DIENE
- Synonyms
- PGF2α-OMe;AGN191129;PGF2ALPHA-OME;UNII-NK1168QB5T;Prostaglandin F2α alcohol methyl ether;PROSTAGLANDIN F2ALPHA ALCOHOL METHYL ETHER;1-METHOXY-9ALPHA, 11ALPHA, 15S-TRIHYDROXYPROSTA-5Z, 13E-DIENE;Prosta-5,13-diene-9,11,15-triol, 1-methoxy-, (5Z,9α,11α,13E,15S)-;(1S,3R,4R,5R)-4-[(E,3S)-3-hydroxyoct-1-enyl]-5-[(Z)-7-methoxyhept-2-enyl]cyclopentane-1,3-diol
- CBNumber
- CB2773317
- Molecular Formula
- C21H38O4
- Formula Weight
- 354.52
- MOL File
- 143656-18-2.mol
1-METHOXY-9ALPHA, 11ALPHA, 15S-TRIHYDROXYPROSTA-5Z, 13E-DIENE Property
- Boiling point:
- 482.1±45.0 °C(Predicted)
- Density
- 1.056±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 7 mg/ml; DMSO: 15 mg/ml; Ethanol: 9 mg/ml; PBS (7.2): 0.16 mg/ml
- pka
- 14.59±0.70(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
H336May cause drowsiness or dizziness
H360May damage fertility or the unborn child
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 16014
- Product name
- Prostaglandin F2α Alcohol methyl ether
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $64
- Updated
- 2024/03/01
- Product number
- 16014
- Product name
- Prostaglandin F2α Alcohol methyl ether
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $280
- Updated
- 2024/03/01
- Product number
- 16014
- Product name
- Prostaglandin F2α Alcohol methyl ether
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $497
- Updated
- 2024/03/01
- Product number
- 1291AH
- Product name
- 1-Methoxy-9alpha,11alpha,15S-trihydroxyprosta-5Z,13E-diene
- Packaging
- 1mg
- Price
- $168
- Updated
- 2021/12/16
- Product number
- LIP0004581
- Product name
- 1-METHOXY-9ALPHA, 11ALPHA, 15S-TRIHYDROXYPROSTA-5Z, 13E-DIENE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.16
- Updated
- 2021/12/16
1-METHOXY-9ALPHA, 11ALPHA, 15S-TRIHYDROXYPROSTA-5Z, 13E-DIENE Chemical Properties,Usage,Production
Uses
Prostaglandin F2α alcohol methyl ether is an alcohol methyl ether G protein-coupled receptor. Prostaglandin F2α is also a luteinizing hormone in sheep and may be a nociceptive mediator in the spinal cord[1][2][3].
Definition
ChEBI: PGF2alpha methyl ether is an aliphatic alcohol.
References
[1] Richie-Jannetta R, et al. Structural determinants for calcium mobilization by prostaglandin E2 and prostaglandin F2alpha glyceryl esters in RAW 264.7 cells and H1819 cells. Prostaglandins Other Lipid Mediat. 2010 Jun;92(1-4):19-24. DOI:10.1016/j.prostaglandins.2010.01.003
[2] Woodward DF, et al. Recent progress in prostaglandin F2α ethanolamide (prostamide F2α) research and therapeutics. Pharmacol Rev. 2013 Jul 26;65(4):1135-47. DOI:10.1124/pr.112.007088
[3] McCracken J A, et al. Prostaglandin F2α identified as a luteolytic hormone in sheep[J]. Nature New Biology, 1972, 238(83): 129-134.
1-METHOXY-9ALPHA, 11ALPHA, 15S-TRIHYDROXYPROSTA-5Z, 13E-DIENE Preparation Products And Raw materials
Raw materials
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