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5-Fluoropyrimidine-4,6-diol

Product Name
5-Fluoropyrimidine-4,6-diol
CAS No.
106615-61-6
Chemical Name
5-Fluoropyrimidine-4,6-diol
Synonyms
5-FLUORO-PYRIMIDINE-4,6-DIOL;4,6-Dihydroxy-5-fluoropyrimidine;5-Fluoro-4,6-dihydroxypyrimidine;5-Fluoro-6-hydroxy-4(3H)-pyrimidinone;5-fluoro-4-hydroxy-1H-pyrimidin-6-one;5-fluoro-6-hydroxypyriMidin-4(3H)-one;4(3H)-PyriMidinone, 5-fluoro-6-hydroxy-;4(1H)-Pyrimidinone, 5-fluoro-6-hydroxy- (9CI);5-fluoro-6-hydroxy-3,4-dihydropyrimidin-4-one;5-FLUORO-PYRIMIDINE-4,6-DIOL ISO 9001：2015 REACH
CBNumber
CB2793070
Molecular Formula
C4H3FN2O2
Formula Weight
130.08
MOL File
106615-61-6.mol
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5-Fluoropyrimidine-4,6-diol Property

Density 
1.73±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
3.42±0.10(Predicted)
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Safety

HazardClass 
IRRITANT
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B435445
Product name
5-Fluoropyrimidine-4,6-diol
Packaging
250mg
Price
$55
Updated
2021/12/16
AK Scientific
Product number
X8810
Product name
5-Fluoropyrimidine-4,6-diol
Packaging
1g
Price
$111
Updated
2021/12/16
Matrix Scientific
Product number
059839
Product name
5-Fluoropyrimidine-4,6-diol
Purity
>96%
Packaging
1g
Price
$124
Updated
2021/12/16
ChemScene
Product number
CS-W000796
Product name
5-fluoropyrimidine-4,6-diol
Packaging
5g
Price
$155
Updated
2021/12/16
Matrix Scientific
Product number
059839
Product name
5-Fluoropyrimidine-4,6-diol
Purity
>96%
Packaging
500mg
Price
$163
Updated
2021/12/16
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5-Fluoropyrimidine-4,6-diol Chemical Properties,Usage,Production

Uses

5-Fluoropyrimidine-4,6-diol is used in preparation of Phenylpyrimidine derivatives and analogs for use as Kynurenine-3-monooxygenase inhibitors.

Preparation

synthesis of 5-Fluoro-4,6-dihydroxypyrimidine: Formamidine acetate (2.06 g, 20 mmol) was added to the solution of sodium (1.38 g, 60 mmol) in anhydrous ethanol (40 mL) and the mixture was heated to reflux. Diethyl 2-fluoromalonate (3.20 g, 18 mmol) was added dropwise over 20 minutes and the mixture was heated at reflux for 6 h. After cooling to room temperature, the solution was evaporated to dryness, the residue was dissolved in water (20 mL), acidified with HCl (5 mL), the precipitate was filtered, washed with water (5 mL), ethanol (2 × 5 mL) and diethyl ether (2 × 5 mL). After drying in vacuo, 5-fluoro-4,6-dihydroxypyrimidine (1.50 g, 64%) was obtained as a brown powder.
m.p.: >300 °C; ([M + H]+ , 131.0244, C4H4FN2O2 requires: [M]+ , 131.0257); IR (neat, cm-1 ) 3053, 2639, 1633, 1547, 1388, 1213; δH (DMSO d6, 400 MHz) 7.90 (1H, s, C-H), 12.38 (2H, bs, OH); δF (DMSO d6, 376 MHz): -178.06 (s); δC (DMSO d6, 100 MHz) 132.79 (d, 1 JCF 235.6, C-F), 144.46 (d, 4 JCF 7.7, C-H), 155.83 (d, 2 JCF 15.0, C-OH); m/z (ASAP) 131 (100%, [M + H]+ ).21a

5-Fluoropyrimidine-4,6-diol Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Fluoropyrimidine-4,6-diol Suppliers

China 113 Europe 1 Germany 1 India 2 United Kingdom 2 United States 14 Global 133
SiChuang NanBu Honesty Technology Co., Ltd.
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0838-5675166 15883665058
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0838-5675535
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nbcxkj@126.com
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China
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Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
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United States
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Adamas Reagent, Ltd.
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400-6009262 16621234537
Fax
021-64823266
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zhangsn@titansci.com
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China
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Nanjing Chemlin Chemical Co., Ltd
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025-83697070
Fax
+86-25-83453306
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info@chemlin.com.cn
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China
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ChangZhou SIDU chemical Co., Ltd.
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0519-81291281 18015082300
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0519-81291281
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siduchem@hotmail.com
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China
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Chengdu Forest Science and Technology Development Co., Ltd.
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028-87925786 18982287581
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028-61777050
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sales@cdforestchem.com
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China
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Nanjing JinruiJiuAn Biotechnology Co., Ltd.
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025-58196018 800028039
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025-83453306
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sales@fartop.net
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China
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Shanghai Topbiochem Technology Co., Ltd
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021-58170097
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info@topbiochem.com
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China
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58
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6181
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58
Shanghai Witofly Chemical Co.,Ltd
Tel
Email
sales@witofly.com
Country
China
ProdList
2867
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View Lastest Price from 5-Fluoropyrimidine-4,6-diol manufacturers

Dideu Industries Group Limited
Product
5-FLUORO-PYRIMIDINE-4,6-DIOL 106615-61-6
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-09
Career Henan Chemical Co
Product
5-FLUORO-PYRIMIDINE-4,6-DIOL 106615-61-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-06-24

106615-61-6, 5-Fluoropyrimidine-4,6-diolRelated Search:

NA 2,5-Diamino-4,6-dihydroxy-pyrimidine 4-Hydroxy-5-fluorpyrimidine 5-Fluoropyrimidine 6-Fluoro-pyrimidine-2,4-diol 2-[(4,6-DIMETHOXY-5-FLUOROPYRIMIDIN-2-YL)OXY]BENZOIC ACID, METHYL ESTER 5-Fluoropyrimidine-4,6-diol FLUOXASTROBIN

  • 5-FLUORO-PYRIMIDINE-4,6-DIOL
  • 4(1H)-Pyrimidinone, 5-fluoro-6-hydroxy- (9CI)
  • 5-Fluoro-4,6-dihydroxypyrimidine
  • 4,6-Dihydroxy-5-fluoropyrimidine
  • 4(3H)-PyriMidinone, 5-fluoro-6-hydroxy-
  • 5-fluoro-6-hydroxypyriMidin-4(3H)-one
  • 5-fluoro-6-hydroxy-3,4-dihydropyrimidin-4-one
  • 5-FLUORO-PYRIMIDINE-4,6-DIOL ISO 9001：2015 REACH
  • 5-fluoro-4-hydroxy-1H-pyrimidin-6-one
  • 5-Fluoro-6-hydroxy-4(3H)-pyrimidinone
  • 106615-61-6
  • Fluorine series
  • PYRIMIDINE