2-AMINO-4-(1'HYDROXYETHYL)-PYRIDINE
- Product Name
- 2-AMINO-4-(1'HYDROXYETHYL)-PYRIDINE
- CAS No.
- 885266-91-1
- Chemical Name
- 2-AMINO-4-(1'HYDROXYETHYL)-PYRIDINE
- Synonyms
- 1-(2-Aminopyridin-4-yl);1-(2-AMINO-PYRIDIN-4-YL)-ETHANOL;2-AMINO-4-(1'HYDROXYETHYL)-PYRIDINE;2-aMino-a-Methyl-4-PyridineMethanol;2-Amino-alpha-methyl-4-pyridinemethanol;4-Pyridinemethanol, 2-amino-.alpha.-methyl-;2-AMINO-4-(1'HYDROXYETHYL)-PYRIDINE ISO 9001:2015 REACH
- CBNumber
- CB2798787
- Molecular Formula
- C7H10N2O
- Formula Weight
- 138.17
- MOL File
- 885266-91-1.mol
2-AMINO-4-(1'HYDROXYETHYL)-PYRIDINE Property
- Boiling point:
- 322.7±27.0 °C(Predicted)
- Density
- 1.191±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 13.44±0.20(Predicted)
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 101912
- Product name
- 1-(2-Aminopyridin-4-yl)ethanol
- Purity
- 95%
- Packaging
- 250mg
- Price
- $283
- Updated
- 2021/12/16
- Product number
- 101912
- Product name
- 1-(2-Aminopyridin-4-yl)ethanol
- Purity
- 95%
- Packaging
- 1g
- Price
- $724
- Updated
- 2021/12/16
- Product number
- 4H30-1-8A
- Product name
- 1-(2-Aminopyridin-4-yl)ethanol
- Packaging
- 1g
- Price
- $797
- Updated
- 2021/12/16
- Product number
- 4164AC
- Product name
- 1-(2-Aminopyridin-4-yl)ethanol
- Packaging
- 1g
- Price
- $1027
- Updated
- 2021/12/16
- Product number
- CHM0070620
- Product name
- 4-PYRIDINEMETHANOL, 2-AMINO-.ALPHA.-METHYL-
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1331.6
- Updated
- 2021/12/16
2-AMINO-4-(1'HYDROXYETHYL)-PYRIDINE Chemical Properties,Usage,Production
Synthesis
42182-25-2
885266-91-1
Under nitrogen protection, 1-(2-aminopyridin-4-yl)ethanone (168 mg, 1.234 mmol) was dissolved in methanol (10 mL) and cooled to 0 °C. Subsequently, sodium borohydride (46.7 mg, 1.234 mmol) was added to the reaction mixture in batches. The reaction mixture was stirred at room temperature for 2 hours. After completion of the reaction, the volatile solvent was removed by distillation under reduced pressure. The residue was dissolved in ethyl acetate (25 mL) and extracted with saturated aqueous sodium bicarbonate (30 mL). The aqueous phase was then back-extracted with ethyl acetate (2 x 20 mL). The organic phases were combined, washed with brine (30 mL), dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 1-(2-aminopyridin-4-yl)ethanol (77 mg, 45% yield) as a yellow oil. The mass spectrum (electrospray positive ion mode) showed m/z 139 ([M+H]+).
References
[1] Journal of Medicinal Chemistry, 2016, vol. 59, # 5, p. 1727 - 1746
[2] Patent: US2016/45512, 2016, A1. Location in patent: Paragraph 0525; 0527
[3] Patent: WO2011/14515, 2011, A1. Location in patent: Page/Page column 123
[4] Patent: US2012/244120, 2012, A1
2-AMINO-4-(1'HYDROXYETHYL)-PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-AMINO-4-(1'HYDROXYETHYL)-PYRIDINE manufacturers
- Product
- 2-AMINO-4-(1'HYDROXYETHYL)-PYRIDINE 885266-91-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-04-30