Substance P TFA
- Product Name
- Substance P TFA
- CAS No.
- 148470-19-3
- Chemical Name
- Substance P TFA
- Synonyms
- Substance P TFA;Substance P xTFA;Neurokinin P TFA;(S)-2-((S)-1-(L-Arginyl-L-prolyl-L-lysyl)pyrrolidine-2-carboxamido)-N1-((S)-5-amino-1-(((S)-1-(((S)-1-((2-(((S)-1-(((S)-1-amino-4-(methylthio)-1-oxobutan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-2-oxoethyl)amino)-1-oxo-3-phenylpropan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)amino)-1,5-dioxopentan-2-yl)pentanediamide 2,2,2-trifluoroacetate
- CBNumber
- CB28050564
- Molecular Formula
- C65H99F3N18O15S
- Formula Weight
- 1461.67
- MOL File
- 148470-19-3.mol
Substance P TFA Property
- storage temp.
- Store at -20°C
- solubility
- Water: 1 mg/ml
- form
- A lyophilized powder
- color
- White to off-white
- Water Solubility
- Water: 100 mg/mL
- Sequence
- Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 24035
- Product name
- Substance P (trifluoroacetate salt)
- Purity
- ≥95%
- Packaging
- 1 mg
- Price
- $44
- Updated
- 2024/03/01
- Product number
- 24035
- Product name
- Substance P (trifluoroacetate salt)
- Purity
- ≥95%
- Packaging
- 5 mg
- Price
- $151
- Updated
- 2024/03/01
- Product number
- 24035
- Product name
- Substance P (trifluoroacetate salt)
- Purity
- ≥95%
- Packaging
- 10 mg
- Price
- $257
- Updated
- 2024/03/01
- Product number
- 24035
- Product name
- Substance P (trifluoroacetate salt)
- Purity
- ≥95%
- Packaging
- 25 mg
- Price
- $479
- Updated
- 2024/03/01
- Product number
- CS-0119378
- Product name
- SubstancePTFA
- Purity
- 99.60%
- Packaging
- 25mg
- Price
- $540
- Updated
- 2021/12/16
Substance P TFA Chemical Properties,Usage,Production
Uses
Substance P TFA (Neurokinin P TFA) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R)[1].
Definition
ChEBI: Substance P is a neuropeptide consisting of 11-amino acids. It preferentially activates neurokinin-1 receptors, exterting excitatory effects on central and peripheral neurons and involved in pain transmission. It has a role as a neurotransmitter, a vasodilator agent and a neurokinin-1 receptor agonist. It is a conjugate base of a substance P(3+).
IC 50
NK1; Human Endogenous Metabolite
References
[1] Grady EF, et al. Delineation of the endocytic pathway of substance P and its seven-transmembrane domain NK1 receptor. Mol Biol Cell. 1995 May;6(5):509-24. DOI:10.1091/mbc.6.5.509
[2] Zhang L, et al. MiR-34b/c-5p and the neurokinin-1 receptor regulate breast cancer cell proliferation and apoptosis. Cell Prolif. 2018 Oct 17:e12527. DOI:10.1111/cpr.12527
Substance P TFA Preparation Products And Raw materials
Raw materials
Preparation Products
Substance P TFA Suppliers
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- 0571-87213919
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