Mito-apocynin (C11)

Product Name: Mito-apocynin (C11)
CAS No.: 1254044-38-6
Chemical Name: Mito-apocynin (C11)
Synonyms: Mito-apocynin (C11);Mito apocynin (C11),Mitoapocynin (C11),Mito-apocynin (C-11);(11-((4-Hydroxy-3-methoxybenzoyl)oxy)undecyl)triphenylphosphonium bromide
CBNumber: CB28054597
Molecular Formula: C37H44BrO4P
Formula Weight: 663.63
MOL File: 1254044-38-6.mol

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Mito-apocynin (C11) Property

storage temp.: Inert atmosphere,Room Temperature
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0115705
Product name: Mito-apocynin(C11)
Purity: 99.79%
Packaging: 50mg
Price: $375
Updated: 2021/12/16

ChemScene

Product number: CS-0115705
Product name: Mito-apocynin(C11)
Purity: 99.79%
Packaging: 100mg
Price: $595
Updated: 2021/12/16

CSNpharm

Product number: CSN25352
Product name: Mito-apocynin-C11
Packaging: 100mg
Price: $550
Updated: 2021/12/16

Ambeed

Product number: A1227982
Product name: (11-((4-Hydroxy-3-methoxybenzoyl)oxy)undecyl)triphenylphosphoniumbromide
Purity: 98+%
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Ambeed

Product number: A1227982
Product name: (11-((4-Hydroxy-3-methoxybenzoyl)oxy)undecyl)triphenylphosphoniumbromide
Purity: 98+%
Packaging: 100mg
Price: $59
Updated: 2021/12/16

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Mito-apocynin (C11) Chemical Properties,Usage,Production

Uses

Mito-apocynin (C11), an orally active mitochondria-targeted triphenylphosphonium (TPP)-based compound, is synthesized by conjugating the Apocynin moiety with a TPP+ cation. Mito-apocynin (C11) selectively targets mitochondria, and shows neuroprotective effect. Mito-apocynin (C11) prevents hyposmia and corrects deficits in motor function[1].

in vivo

Mito-apocynin-C11 (3 mg/kg; oral gavage; 3x/wk from 3 months of age until 15 months) markedly improves the coordinated motor function and olfactory function in LRRK2R1441G mice^[1].

Animal Model:	LRRK2R1441G mice^[1]
Dosage:	3 mg/kg
Administration:	Oral gavage; 3x/wk from 3 months of age until 15 months
Result:	Markedly improved the coordinated motor function and olfactory function.

References

[1] Dranka BP, et al. A novel mitochondrially-targeted apocynin derivative prevents hyposmia and loss of motor function in the leucine-rich repeat kinase 2 (LRRK2(R1441G)) transgenic mouse model of Parkinson's disease. Neurosci Lett. 2014 Nov 7;583:159-64. DOI:10.1016/j.neulet.2014.09.042

Mito-apocynin (C11) Preparation Products And Raw materials

Raw materials

Preparation Products

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Mito-apocynin (C11) Suppliers

China 7 United States 1 Global 8

Tianjin Kailiqi Biotechnology Co., Ltd.

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RD International Technology Co., Limited

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Chengdu Peter-like Biotechnology Co., Ltd.

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Guangzhou Lucheng Biotechnology Co., Ltd.

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1254044-38-6, Mito-apocynin (C11)Related Search:

Mito-apocynin (C11)

(11-((4-Hydroxy-3-methoxybenzoyl)oxy)undecyl)triphenylphosphonium bromide

Mito apocynin (C11),Mitoapocynin (C11),Mito-apocynin (C-11)

1254044-38-6