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Mal-amido-PEG12-NHS ester

Product Name
Mal-amido-PEG12-NHS ester
CAS No.
2101722-60-3
Chemical Name
Mal-amido-PEG12-NHS ester
Synonyms
Mal-dPEG12-NHS Ester;4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxa-40-azatritetracontanoic acid, 43-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-41-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber
CB28054744
Molecular Formula
C38H63N3O19
Formula Weight
865.92
MOL File
2101722-60-3.mol
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Mal-amido-PEG12-NHS ester Property

Density 
1.27±0.1 g/cm3(Predicted)
storage temp. 
-20°C, stored under nitrogen, away from moisture
form 
Solid-Liquid Mixture
pka
15.01±0.46(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-22217
Product name
Mal-amido-PEG12-NHS
Purity
95%
Packaging
100mg
Price
$340
Updated
2021/12/16
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Mal-amido-PEG12-NHS ester Chemical Properties,Usage,Production

Description

Mal-amido-PEG12-NHS is a PEG linker containing a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Mal-amido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Mal-amido-PEG12-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Mal-amido-PEG12-NHS ester Suppliers

Chengdu Pukang Biotechnology Co., Ltd
Tel
+86-028-82550498 +86-19102685862
Fax
086-28-82550468
Email
sales@pu-kang.com
Country
China
ProdList
497
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1245
Advantage
55
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Wuhan Borenpharm Co., Ltd
Tel
027-65563561 18717150066
Fax
027-59218822
Email
3207347307@qq.com
Country
CHINA
ProdList
1238
Advantage
58
Shaanxi borno biotechnology co., LTD
Tel
+86-13759708231
Email
asherw9@hotmail.com
Country
China
ProdList
2373
Advantage
58
Shanghai Tekanbio Pharm-Tech Co., Ltd.
Tel
021-50896099 18017206244
Fax
QQ:3268640975
Email
sales@tekanbio.com
Country
China
ProdList
107
Advantage
58
Zhengzhou Akem Chemical Co., Ltd
Tel
13303867194
Email
3001317055@qq.com
Country
China
ProdList
9681
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
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View Lastest Price from Mal-amido-PEG12-NHS ester manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Mal-amido-PEG12-NHS 2101722-60-3
Price
US $0.00/mg
Min. Order
250mg
Purity
>95.00%
Supply Ability
250mg
Release date
2024-03-27

2101722-60-3, Mal-amido-PEG12-NHS esterRelated Search:


  • 4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxa-40-azatritetracontanoic acid, 43-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-41-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
  • Mal-dPEG12-NHS Ester
  • 2101722-60-3