Mal-amido-PEG12-NHS ester

Product Name: Mal-amido-PEG12-NHS ester
CAS No.: 2101722-60-3
Chemical Name: Mal-amido-PEG12-NHS ester
Synonyms: Mal-dPEG12-NHS Ester;4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxa-40-azatritetracontanoic acid, 43-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-41-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber: CB28054744
Molecular Formula: C38H63N3O19
Formula Weight: 865.92
MOL File: 2101722-60-3.mol

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Mal-amido-PEG12-NHS ester Property

Density: 1.27±0.1 g/cm3(Predicted)
storage temp.: -20°C, stored under nitrogen, away from moisture
form: Solid-Liquid Mixture
pka: 15.01±0.46(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22217
Product name: Mal-amido-PEG12-NHS
Purity: 95%
Packaging: 100mg
Price: $340
Updated: 2021/12/16

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Mal-amido-PEG12-NHS ester Chemical Properties,Usage,Production

Description

Mal-amido-PEG12-NHS is a PEG linker containing a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Mal-amido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Mal-amido-PEG12-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Mal-amido-PEG12-NHS ester Suppliers

China 29 United States 3 Global 32

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354;
Email: support@targetmol.com
Country: United States
ProdList: 39035
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 52923
Advantage: 58

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View Lastest Price from Mal-amido-PEG12-NHS ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Mal-amido-PEG12-NHS 2101722-60-3
Price: US $0.00/mg
Min. Order: 250mg
Purity: >95.00%
Supply Ability: 250mg
Release date: 2024-03-27

2101722-60-3, Mal-amido-PEG12-NHS esterRelated Search:

Mal-amido-PEG1-DNP Mal-amido-PEG4-DNP Mal-amido-PEG11-acid Mal-amido-PEG12-DNP Mal-amido-PEG5-C2-NHS ester Mal-amido-PEG11-DNP Mal-amido-PEG11-NHS Mal-amido-PEG10-DNP Mal-amido-PEG5-DNP

4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxa-40-azatritetracontanoic acid, 43-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-41-oxo-, 2,5-dioxo-1-pyrrolidinyl ester

Mal-dPEG12-NHS Ester

2101722-60-3